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Receptor on natural killer (NK) cells for class I MHC..
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Mouse (Murine) Monoclonal LY-49I Primary Antibody for FACS - ABIN371091
Coles, McMahon, Takizawa, Raulet: Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. in European journal of immunology 2000
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Mouse (Murine) Monoclonal LY-49I Primary Antibody for FACS - ABIN371089
Ljunggren, Kärre: In search of the 'missing self': MHC molecules and NK cell recognition. in Immunology today 1990
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The repertoire of inhibitory Ly49 receptors may be formed under the influenced of Fyn-dependent NK cell activation as well as the respective MHC class I environment.
mouse cytomegalovirus(MCMV) m157 protein binds to Ly49I
Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family.
Contrary to findings in other inhibitory LY49 transgenic systems, no defects in T cell function are observed in Ly49I transgenic FVB mice.
NK cells' own MHC-I significantly masks the Ly49A and Ly49C, but not the Ly49I receptor. Nevertheless, Ly49I was partly masked on transfected tumor cells, suggesting that the structure of Ly49I is compatible in principal with cis binding of MHC-I.
Receptor on natural killer (NK) cells for class I MHC.