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La Ribonucleoprotein Domain Family, Member 7 Proteins (LARP7)

LARP7 encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). Additionally we are shipping LARP7 Antibodies (43) and LARP7 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LARP7 51574 Q4G0J3
LARP7 28036 Q05CL8
Rat LARP7 LARP7 686883 Q5XI01
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Top LARP7 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

LARP7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for La Ribonucleoprotein Domain Family, Member 7 (LARP7) Interaction Partners

Zebrafish La Ribonucleoprotein Domain Family, Member 7 (LARP7) interaction partners

  1. The balance of Cdk9 (show CDK9 Proteins) and Larp7 plays a key role in cardiomyocyte proliferation and response to injury

Human La Ribonucleoprotein Domain Family, Member 7 (LARP7) interaction partners

  1. protein HEXIM (show HEXIM1 Proteins) with 7SKsnRNP complex comprising the non-coding RNA 7SK and proteins MePCE (show MEPCE Proteins) and LARP7.

  2. results suggest that LARP7 uses both its N- and C-terminal domains to stabilize 7SK in a closed structure, which forms by joining conserved sequences at the 5'-end with the foot of the 3' hairpin and has thus functional implications

  3. LARP7 suppresses P-TEFb (show CCNT1 Proteins) activity to inhibit breast cancer progression and metastasis.

  4. LARP7 is most likely recruited to the HIV-1 promoter in the presence of hnRNP A1 (show HNRNPA1 Proteins).

  5. The results demonstrate that the La modules of the human LARP7 is also active in tRNA-mediated suppression, even in the absence of stable UUU-3'OH trailer protection.

  6. Mediator MED23 (show MED23 Proteins) regulates basal transcription in vivo via an interaction with P-TEFb (show CCNT1 Proteins).

  7. Loss of function mutation in LARP7, chaperone of 7SK ncRNA, causes a syndrome of facial dysmorphism, intellectual disability, and primordial dwarfism

  8. LARP7 downregulation occurs early during gastric tumorigenesis and may promote gastric tumorigenesis via p-TEFb (show CCNT1 Proteins) dysregulation.

  9. 7SK RNA thus establishes gene-dependent plasticity between HMGA1 (show HMGA1 Proteins) chromatin remodeling and transcription initiation and P-TEFb (show CCNT1 Proteins) transcription elongation.

  10. A combination of restrictive chromatin structures at the HIV long terminal repeat and limiting P-TEFb (show CCNT1 Proteins) levels contribute to transcriptional silencing leading to latency in primary CD4 (show CD4 Proteins)(+) T cells.

Mouse (Murine) La Ribonucleoprotein Domain Family, Member 7 (LARP7) interaction partners

  1. LARP7 interacts with TUT1 (show TUT1 Proteins) nucleotidyl transferase to regulate Lin28 (show LIN28A Proteins) expression.

LARP7 Protein Profile

Protein Summary

This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with LARP7

  • La ribonucleoprotein domain family, member 7 (LARP7)
  • La ribonucleoprotein domain family, member 7 (LOC100222278)
  • La ribonucleoprotein domain family, member 7 (LOC100356215)
  • La ribonucleoprotein domain family, member 7 (larp7)
  • La ribonucleoprotein domain family, member 7 (Larp7)
  • La ribonucleoprotein domain family, member 7-like (Larp7l)
  • ALAZS protein
  • C330027G06Rik protein
  • D3Wsu161e protein
  • fa10g04 protein
  • Larp7 protein
  • PIP7S protein
  • wu:fa10g04 protein
  • zgc:56476 protein

Protein level used designations for LARP7

La ribonucleoprotein domain family, member 7 , la-related protein 7-like , HDCMA18P protein , la-related protein 7 , P-TEFb-interaction protein for 7SK stability

GENE ID SPECIES
703731 Macaca mulatta
100467107 Ailuropoda melanoleuca
738277 Pan troglodytes
100010450 Monodelphis domestica
100064225 Equus caballus
100222278 Taeniopygia guttata
100356215 Oryctolagus cuniculus
100400841 Callithrix jacchus
100431738 Pongo abelii
100541663 Meleagris gallopavo
100552858 Anolis carolinensis
100583289 Nomascus leucogenys
100627397 Sus scrofa
334956 Danio rerio
422690 Gallus gallus
51574 Homo sapiens
478519 Canis lupus familiaris
505053 Bos taurus
28036 Mus musculus
686883 Rattus norvegicus
691210 Rattus norvegicus
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