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LDHB encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Additionally we are shipping Lactate Dehydrogenase B Proteins (51) and Lactate Dehydrogenase B Kits (35) and many more products for this protein.
Showing 10 out of 137 products:
Human Monoclonal LDHB Primary Antibody for IF, IHC (p) - ABIN561653
Len, Powner, Zhu, Hageman, Song, Fruttiger, Gillies: Pilot application of iTRAQ to the retinal disease Macular Telangiectasia. in Journal of proteome research 2012
Show all 3 Pubmed References
Human Polyclonal LDHB Primary Antibody for ICC, IF - ABIN4890710
Schild, Ruhs, Beiter, Zügel, Hudemann, Reimer, Krumholz-Wagner, Wagner, Keller, Eder, Krüger, Krüger, Braun, Nieß, Steinacker, Mooren: Basal and exercise induced label-free quantitative protein profiling of m. vastus lateralis in trained and untrained individuals. in Journal of proteomics 2015
The NADH-cofactor binding site of pig heart LDH is involved in the interaction with acidic phospholipids, in the pig skeletal muscle LDH, neither the cofactor binding site nor the subunit interfacing areas seem to be involved in the interaction.
Molecular characterization and expression pattern of the equine lactate dehydrogenase B genes
this study shows that low base line lactate dehydrogenase is linked with a better tumor response, and that prolonged overall survival and progression-free survival are observed for patients under ipilimumab treatment with no increase in lactate dehydrogenase
our study examines the inclusion of salivary LDH as potential diagnostic parameter and therapeutic index in Oral squamous cell carcinoma
addition of exogenous lactic acid to growth media was sufficient to induce cell death that could be inhibited by the expression of LDHB. the results suggest that lactate dehydrogenase is a general suppressor of programmed cell death in yeast.
The aim of this study was to demonstrate the effects of 6-week low-intensity training on changes in indicators of aerobic capacity and on HSPA1A (show HSPA1A Antibodies), HSPB1 (show HSPB1 Antibodies), and LDHb expression in white blood cells in high level rowers.
Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma.
The readthrough-extended lactate dehydrogenase subunit LDHBx can also co-import LDHA, the other LDH subunit, into peroxisomes.
In this study, we inhibited LDH using oxamate resulting in the inhibition of proliferation and induction of apoptosis in gastric cancer
We were able to provide evidence that methylation of HLTF and especially HPP1 detected in serum is strongly correlated with cell death in CRC using LDH as surrogate marker
This meta-analysis shows that high serum LDH level is obviously associated with lower overall survival rate in patients with osteosarcoma, and it is an effective biomarker of prognosis.
These observations support prospective clinical evaluation of LDHB as a predictive marker of response for patients with breast cancer receiving neoadjuvant chemotherapy.
these results identified a previously unrecognized Ldhb-driven alteration in muscle mitochondrial function and suggested a mechanism for the adaptive metabolic response induced by exercise training.
Findings suggest that RANKL protein-induced lactate dehydrogenase (LDH) activation stimulates glycolytic and mitochondrial respiratory metabolism via transcription factor NFATc1 signaling.
drs (show SRPX Antibodies) regulates glucose metabolism via LDH-B. Downregulating drs (show SRPX Antibodies) may contribute to the Warburg effect, which is closely associated with malignant progression of cancer cells.
Exercise-induced changes in tumour LDH-B and MCT1 (show MCTS1 Antibodies) expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice
Data show that PI3K/Akt (show AKT1 Antibodies) signalling pathway and lactate dehydrogenase (LDH) play a crucial role in increase of cardiac ATP-binding cassette transporter sub-family C member 9 (SUR2A (show ABCC9 Antibodies)) induced by in vivo exposure to 18% oxygen.
PGC-1alpha in skeletal muscle drives the expression of lactate dehydrogenase (LDH) B in an estrogen-related receptor-alpha-dependent manner.
the Ldhb gene, which encodes the H isoform of lactate dehydrogenase, as a robust PPARgamma (show PPARG Antibodies) target in trophoblasts.
findings offer proof of concept for targeting LDHB as a therapeutic strategy in cancers driven by aberrant activation of the RTK-PI3K-AKT (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) signaling cascade
The increased LDH-A (show LDHA Antibodies)/LDH-B ratio causes high brain lactate levels, which, in turn, are predictive of aging phenotypes.
beta-agonists increased serum LDH levels, but it was not due to release from the heart.
This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
L-lactate dehydrogenase B
, L-lactate dehydrogenase B chain
, LDH heart subunit
, lactate dehydrogenase B
, lactate dehydrogenase H chain
, renal carcinoma antigen NY-REN-46
, lactate dehydrogenase 2, B chain
, lactate dehydrogenase-B
, Lactate dehydrogenease B
, lactate dehydrogenase-H