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anti-Lamin B Receptor (LBR) Antibodies

The protein encoded by LBR belongs to the ERG4/ERG24 family. Additionally we are shipping Lamin B Receptor Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LBR 3930 Q14739
LBR 98386 Q3U9G9
LBR 89789 O08984
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Top anti-Lamin B Receptor Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LBR  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: RPMI 8226 cell lysate  LBR is supported by BioGPS gene expression data to be expressed in RPMI 8226 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti Lamin B Receptor Polyclonal Antibody, Unconjugated (ABIN709391) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded humanlung carcinoma labeled with Rabbit Anti Lamin B Receptor Polyclonal Antibody, Unconjugated (ABIN709391) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB Lamin B Receptor antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

LBR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Lamin B Receptor Interaction Partners

Fruit Fly (Drosophila melanogaster) Lamin B Receptor (LBR) interaction partners

  1. dLBR is not a limiting component of the nuclear architecture in Drosophila cells during the first 2 days of development

Zebrafish Lamin B Receptor (LBR) interaction partners

  1. Data indicate that the LBR of zebrafish and mammals are both required for correct development of embryos.

Xenopus laevis Lamin B Receptor (LBR) interaction partners

  1. LBR targets the membrane precursor vesicles to chromatin by interacting with importin beta (show KPNB1 Antibodies) in a LBR phosphorylation-dependent manner during the NE assembly at the end of mitosis

Human Lamin B Receptor (LBR) interaction partners

  1. Lamin B receptor mRNA expression was directly associated with tumor grade in breast cancer patients(grade 1 vs. grade 3 - 0.00 vs. 0.00; p = 0.0479) and Nottingham Prognostic Index (NPI1 (show KPNA1 Antibodies) vs. NPI3 - 0.00 vs. 0.00; p = 0.0551).

  2. Mutation in LBR gene is associated with pelger-huet anomaly and a mild skeletal phenotype.

  3. Lymphohematopoietic licence: sterol C-14 reductase activity of lamin B receptor (Lbr) is essential for neutrophil differentiation.

  4. LBR missense mutations can abolish sterol reductase activity, causing lethal Greenberg dysplasia but not Pelger anomaly

  5. The LBR knockdown cells retain an ovoid shaped nucleus with reduced levels of lamin A/C (show LMNA Antibodies) during in vitro granulopoiesis induced with retinoic acid.

  6. Our studies reveal for the first time a mechanism that controls the timing of nuclear envelope reassembly through modification of the integral nuclear membrane protein lamin B receptor

  7. LBR is heavily expressed in papillary thyroid carcinoma cells, but an abnormal folding of the protein might explain its lack of immunohistochemical reactivity and be associated with the anomalous folding of the nuclear membrane.

  8. LBR targets the membrane precursor vesicles to chromatin by interacting with importin beta (show KPNB1 Antibodies) in a LBR phosphorylation-dependent manner during the NE assembly at the end of mitosis

  9. LBR mutant variants and sterol reductases can severely interfere with the regular organization of the nuclear envelope and the endoplasmic reticulum.

  10. results suggest that LMNA (show LMNA Antibodies), ZMPSTE24 (show Zmpste24 Antibodies), and LBR sequence variations are not major genetic determinants involved in scleroderma pathogenesis

Mouse (Murine) Lamin B Receptor (LBR) interaction partners

  1. These results show a moderate skin differentiation phenotype, which indicates that upregulation of LBR is not the sole contributor to the Hutchinson-Gilford progeria syndrome phenotype.

  2. The N-terminal portion of LBR is probably responsible for the binding to HP1b (show CBX1 Antibodies).

  3. Study identified LBR- and lamin-A/C (show LMNA Antibodies)-dependent mechanisms tethering heterochromatin to the nuclear envelope. The two tethers are sequentially used during cellular differentiation and development: first the LBR- and then the lamin-A/C (show LMNA Antibodies)-dependent tether.

  4. LBR deficiency affects not only nuclear architecture but also proliferation, cell viability, and gene expression of hematopoietic cells

  5. sterol Delta(14) reductase domain of LBR plays a critical role in cholesterol biosynthesis and that this process is essential to both myeloid cell growth and functional maturation.

  6. Lbr, under transcriptional regulation of C/EBPepsilon (show CEBPE Antibodies), is necessary for morphological but not necessarily functional granulocyte maturation.

  7. lamin B receptor, although residing in nuclear membranes, may contribute to cholesterol biosynthesis in Tm7sf2 (show TM7SF2 Antibodies)((-/-)) mice

Lamin B Receptor (LBR) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Gene names and symbols associated with anti-Lamin B Receptor (LBR) Antibodies

  • lamin B receptor (LBR) antibody
  • Lamin B receptor (LBR) antibody
  • lamin B receptor (lbr) antibody
  • lamin B receptor (lbr-A) antibody
  • lamin B receptor (Lbr) antibody
  • AI505894 antibody
  • CG17952 antibody
  • DHCR14B antibody
  • dLBR antibody
  • Dmel\\CG17952 antibody
  • ic antibody
  • LBR antibody
  • lbr-A antibody
  • LMN2R antibody
  • Nbp60 antibody
  • p58 gene antibody
  • PHA antibody
  • sb:cb406 antibody
  • TDRD18 antibody
  • wu:fb75h08 antibody
  • wu:fc47b04 antibody
  • wu:fd36b07 antibody
  • Xp58 antibody
  • zgc:86649 antibody

Protein level used designations for anti-Lamin B Receptor (LBR) Antibodies

CG17952-PA , CG17952-PB , CG17952-PC , LBR-PA , LBR-PB , LBR-PC , lamin B receptor , lamin-B receptor , lamin-B receptor-like , integral nuclear envelope inner membrane protein , tudor domain containing 18 , ichthyosis , Lamin-B receptor

GENE ID SPECIES
100056997 Equus caballus
37482 Drosophila melanogaster
368360 Danio rerio
378609 Xenopus laevis
457776 Pan troglodytes
490391 Canis lupus familiaris
700801 Macaca mulatta
100145693 Xenopus (Silurana) tropicalis
100415074 Callithrix jacchus
100470463 Ailuropoda melanoleuca
100594061 Nomascus leucogenys
3930 Homo sapiens
98386 Mus musculus
89789 Rattus norvegicus
509348 Bos taurus
396285 Gallus gallus
100174610 Pongo abelii
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