Lamin B Receptor (LBR) ELISA Kits

The protein encoded by LBR belongs to the ERG4/ERG24 family. Additionally we are shipping Lamin B Receptor Antibodies (53) and Lamin B Receptor Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LBR LBR 3930 Q14739
Anti-Mouse LBR LBR 98386 Q3U9G9
Anti-Rat LBR LBR 89789 O08984
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More ELISA Kits for Lamin B Receptor Interaction Partners

Fruit Fly (Drosophila melanogaster) Lamin B Receptor (LBR) interaction partners

  1. dLBR is not a limiting component of the nuclear architecture in Drosophila cells during the first 2 days of development

Zebrafish Lamin B Receptor (LBR) interaction partners

  1. Data indicate that the LBR of zebrafish and mammals are both required for correct development of embryos.

Xenopus laevis Lamin B Receptor (LBR) interaction partners

  1. LBR targets the membrane precursor vesicles to chromatin by interacting with importin beta (show KPNB1 ELISA Kits) in a LBR phosphorylation-dependent manner during the NE assembly at the end of mitosis

Human Lamin B Receptor (LBR) interaction partners

  1. These observations point to a new mechanism regulating the localization of LBR, which is governed by an ELYS-mediated phosphorylation network.

  2. The primary response of cells to various stresses leading to senescence consists of the down-regulation of LBR and LB1 (show CKAP2 ELISA Kits) to attain reversal of the chromatin architecture.

  3. We have shown here that lamin B receptor (LBR) showed a change in localization in both BrdU-induced and replicative senescent cells.

  4. Data indicate that proto-oncogene (show RAB1A ELISA Kits) protein c (show PROC ELISA Kits)-akt (Akt (show AKT1 ELISA Kits)) phosphorylates distinct sites than SRPK1 (show SRPK1 ELISA Kits) protein within the arginine-serine (RS) domain of Lamin B Receptor (LBR).

  5. Lamin B receptor mRNA expression was directly associated with tumor grade in breast cancer patients(grade 1 vs. grade 3 - 0.00 vs. 0.00; p = 0.0479) and Nottingham Prognostic Index (NPI1 (show KPNA1 ELISA Kits) vs. NPI3 - 0.00 vs. 0.00; p = 0.0551).

  6. Mutation in LBR gene is associated with pelger-huet anomaly and a mild skeletal phenotype.

  7. Lymphohematopoietic licence: sterol C-14 reductase activity of lamin B receptor (Lbr) is essential for neutrophil differentiation.

  8. LBR missense mutations can abolish sterol reductase activity, causing lethal Greenberg dysplasia but not Pelger anomaly

  9. The LBR knockdown cells retain an ovoid shaped nucleus with reduced levels of lamin A/C (show LMNA ELISA Kits) during in vitro granulopoiesis induced with retinoic acid.

  10. Our studies reveal for the first time a mechanism that controls the timing of nuclear envelope reassembly through modification of the integral nuclear membrane protein lamin B receptor

Mouse (Murine) Lamin B Receptor (LBR) interaction partners

  1. The diffusional mobility of full-length LBR shows significant regional variation along the nuclear envelope, consistent with the existence of discrete LBR microdomains and the occurrence of multiple, asymmetrically-spaced anastomoses along the nuclear envelope-endoplasmic reticulum interface. Native LBR may be "configured" by long-range interactions between adjacent transmembrane domains and parts of the NH2 region.

  2. These results show a moderate skin differentiation phenotype, which indicates that upregulation of LBR is not the sole contributor to the Hutchinson-Gilford progeria syndrome phenotype.

  3. The N-terminal portion of LBR is probably responsible for the binding to HP1b (show CBX1 ELISA Kits).

  4. Study identified LBR- and lamin-A/C (show LMNA ELISA Kits)-dependent mechanisms tethering heterochromatin to the nuclear envelope. The two tethers are sequentially used during cellular differentiation and development: first the LBR- and then the lamin-A/C (show LMNA ELISA Kits)-dependent tether.

  5. LBR deficiency affects not only nuclear architecture but also proliferation, cell viability, and gene expression of hematopoietic cells

  6. sterol Delta(14) reductase domain of LBR plays a critical role in cholesterol biosynthesis and that this process is essential to both myeloid cell growth and functional maturation.

  7. Lbr, under transcriptional regulation of C/EBPepsilon (show CEBPE ELISA Kits), is necessary for morphological but not necessarily functional granulocyte maturation.

  8. lamin B receptor, although residing in nuclear membranes, may contribute to cholesterol biosynthesis in Tm7sf2 (show TM7SF2 ELISA Kits)((-/-)) mice

Lamin B Receptor (LBR) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Gene names and symbols associated with Lamin B Receptor (LBR) ELISA Kits

  • lamin B receptor (LBR) antibody
  • Lamin B receptor (LBR) antibody
  • lamin B receptor (lbr) antibody
  • lamin B receptor S homeolog (lbr.S) antibody
  • lamin B receptor (Lbr) antibody
  • AI505894 antibody
  • CG17952 antibody
  • DHCR14B antibody
  • dLBR antibody
  • Dmel\\CG17952 antibody
  • ic antibody
  • LBR antibody
  • lbr-A antibody
  • LMN2R antibody
  • Nbp60 antibody
  • p58 gene antibody
  • PHA antibody
  • sb:cb406 antibody
  • TDRD18 antibody
  • wu:fb75h08 antibody
  • wu:fc47b04 antibody
  • wu:fd36b07 antibody
  • Xp58 antibody
  • zgc:86649 antibody

Protein level used designations for Lamin B Receptor (LBR) ELISA Kits

CG17952-PA , CG17952-PB , CG17952-PC , LBR-PA , LBR-PB , LBR-PC , lamin B receptor , lamin-B receptor , lamin-B receptor-like , integral nuclear envelope inner membrane protein , tudor domain containing 18 , ichthyosis , Lamin-B receptor

100056997 Equus caballus
37482 Drosophila melanogaster
368360 Danio rerio
378609 Xenopus laevis
457776 Pan troglodytes
490391 Canis lupus familiaris
700801 Macaca mulatta
100145693 Xenopus (Silurana) tropicalis
100415074 Callithrix jacchus
100470463 Ailuropoda melanoleuca
100594061 Nomascus leucogenys
3930 Homo sapiens
98386 Mus musculus
89789 Rattus norvegicus
509348 Bos taurus
396285 Gallus gallus
100174610 Pongo abelii
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