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anti-Laminin, alpha 2 (LAMA2) Antibodies

Laminin, an extracellular protein, is a major component of the basement membrane. Additionally we are shipping Laminin Kits (3) and Laminin Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAMA2 3908 P24043
LAMA2 16773  
LAMA2 309368  
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Top anti-Laminin Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to LAMA2 on formalin-fixed paraffin-embedded human pancreas (antibody concentration 1 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to LAMA2 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 1 ug/ml] Detection limit for recombinant GST tagged LAMA2 is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Anti-Laminin 2 alpha antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: A549 Cell Lysate Lane 3: PANC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human bladder carcinoma labeled with Rabbit Anti LAMA2 Polyclonal Antibody, Unconjugated (ABIN1387552) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using LAMA2 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of NIH-3T3 cells, using LAMA2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

LAMA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Laminin Antibodies

  1. Human Monoclonal Laminin Primary Antibody for IHC (p), ELISA - ABIN395519 : Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010 (PubMed)
    Show all 5 references for ABIN395519

  2. Human Monoclonal Laminin Primary Antibody for IHC (p), ELISA - ABIN561638 : Lemons, Feng, Bennett, Legesse-Miller, Johnson, Raitman, Pollina, Rabitz, Rabinowitz, Coller: Quiescent fibroblasts exhibit high metabolic activity. in PLoS biology 2010 (PubMed)
    Show all 2 references for ABIN561638

More Antibodies against Laminin Interaction Partners

Zebrafish Laminin, alpha 2 (LAMA2) interaction partners

  1. The degenerative muscle phenotype in the zebrafish dystrophic mutant, candyfloss (caf) results from mutations in the laminin alpha2 (lama2) gene.

Human Laminin, alpha 2 (LAMA2) interaction partners

  1. By analyzing the gene test we found that compound heterozygous LAMA2 mutation inherited from the parents. One coming from the father was a gross deletion expanding from exon 36 to exon 65. The from the mother was a missense mutation c.1358G>C

  2. This report widens the clinical spectrum of cerebral manifestations related with mutations in LAMA2

  3. Data showed miR (show MLXIP Antibodies)-29a/c as novel regulators of LAMA2 in ependymoma based on miRNA-mRNA covariation and sequence-based target predictions.

  4. This study demonstrates a wide clinical spectrum of LAMA2-related muscular dystrophy and its prevalence in an LGMD2 (show CAPN3 Antibodies) cohort, which indicates that LAMA2 muscular dystrophy should be included in the LGMD2 (show CAPN3 Antibodies) nomenclature.

  5. Crystal structure of LAMM L4 domain

  6. Data find high frequency mutations in LAMA2 protein in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) patients. Its lower expression levels correlate with tumor progression, poor survival and higher chance of cancer recurrence.

  7. 2 patients with partial laminin-alpha2 deficiency and atypical phenotypes, one with almost exclusive central nervous system involvement and second with cardiac dysfunction, rigid spine syndrome and limb-girdle weakness; both have 2 heterozygous LAMA2 variants sharing a potentially pathogenic missense mutation c.2461A>C located in exon 18

  8. Genetic association studies identified two pathogenic mutations in the LAMA2 gene in patients with congenital muscular dystrophy.

  9. Homozygous truncating mutations in POMK lead to congenital muscular dystrophies with secondary merosin deficiency, hypomyelination and intellectual disability.

  10. children with LAMA2 congenital muscular dystrophy may be at nogreater risk of developing malignant hyperthermia than the general population

Mouse (Murine) Laminin, alpha 2 (LAMA2) interaction partners

  1. results indicate a novel role for laminin-dystroglycan (show DAG1 Antibodies) interactions in the cooperative integration of astrocytes, endothelial cells, and pericytes in regulating the Blood Brain Barrier.

  2. Laminin alpha2-mediated FAK (show PTK2 Antibodies) activation in podocytes is an important early event in Alport glomerular pathogenesis.

  3. The effects of merosin knockout on alkaline phosphatase activity in the liver of normal and dystrophic mice is reported.

  4. The data of this study suggested that prosurvival Lama (show LAMA1 Antibodies) interactions in the developing postnatal VZ-SVZ germinal zone regulate the ability, or timing, of oligodendrocyte production to occur appropriately.

  5. Levels of both lipid rafts and raft-located acetylcholinesterase (show AChE Antibodies) dimers increase in muscle of mice with muscular dystrophy by merosin deficiency.

  6. Overexpression of laminin alpha1 chain that lacks the dystroglycan (show DAG1 Antibodies) binding LG4-5 domains in alpha2 chain deficient mice resulted in prolonged lifespan and improved health.

  7. Ku70 (show XRCC6 Antibodies) is a regulator of Bax (show BAX Antibodies)-mediated pathogenesis in laminin-alpha2-deficiency muscle cells.

  8. this study identified a novel spontaneous mouse model of human congenital muscular dystrophy with laminin alpha2 chain deficiency, named dy(Pas (show PASK Antibodies))/dy(Pas (show PASK Antibodies)). Homozygous animals rapidly developed a progressive muscular dystrophy leading to premature death.

  9. merosin contributes to muscle passive stiffness, viscoelasticity, and contractility

  10. Data show that merosin deficiency reduces fatigue and prolongs the duration of force potentiation in sternohyoid muscle from an animal model of merosin-deficient congenital muscular dystrophy.

Laminin (LAMA2) Antigen Profile

Protein Summary

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Gene names and symbols associated with LAMA2

  • laminin, alpha 2 (LAMA2) antibody
  • laminin, alpha 2 (lama2) antibody
  • laminin, alpha 2 (Lama2) antibody
  • 5830440B04 antibody
  • dy antibody
  • LAMA2 antibody
  • LAMM antibody
  • mer antibody
  • merosin antibody
  • mKIAA4087 antibody

Protein level used designations for LAMA2

laminin alpha 2 subunit , laminin, alpha 2 (merosin, congenital muscular dystrophy) , laminin, alpha 2 , caf , candyfloss , laminin alpha 2 chain , unm teg15a , unm tk209 , laminin subunit alpha-2-like , laminin M chain , laminin subunit alpha-2 , laminin-12 subunit alpha , laminin-2 subunit alpha , laminin-4 subunit alpha , merosin heavy chain , dystrophia muscularis

GENE ID SPECIES
472122 Pan troglodytes
484121 Canis lupus familiaris
100049705 Danio rerio
100405831 Callithrix jacchus
100460380 Pongo abelii
100484712 Ailuropoda melanoleuca
100545053 Meleagris gallopavo
100565785 Anolis carolinensis
100583654 Nomascus leucogenys
3908 Homo sapiens
100350500 Oryctolagus cuniculus
16773 Mus musculus
309368 Rattus norvegicus
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