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Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Additionally we are shipping LAMA3 Kits (12) and LAMA3 Proteins (3) and many more products for this protein.
Showing 10 out of 44 products:
Human Polyclonal LAMA3 Primary Antibody for ELISA - ABIN250910
Dietze, Bowie, Mrózek, Caldwell, Neal, Marjoram, Troch, Bean, Yokoyama, Ibarra, Seewaldt: CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5. in Journal of cell science 2005
Human Polyclonal LAMA3 Primary Antibody for IHC, IHC (p) - ABIN4330106
Kuhn, Kurman, Soslow, Han, Sehdev, Morin, Wang, Shih: The diagnostic and biological implications of laminin expression in serous tubal intraepithelial carcinoma. in The American journal of surgical pathology 2012
A 6589-bp deletion spanning exons 24-27 was found in the LAMA3 gene in American Saddlebred foals born with the skin-blistering condition epitheliogenesis imperfecta
Seventeen percent of the patients were compound heterozygous or homozygous for mutations in the gene LAMA3, 59% carried mutations in both alleles of LAMB3 (show LAMB3 Antibodies), and 12% were homozygous for mutations in LAMC2 (show LAMC2 Antibodies). In nine patients with severe generalized JEB, detection of two mutations in one of the genes LAMA3, LAMB3 (show LAMB3 Antibodies), or LAMC2 (show LAMC2 Antibodies) was not possible, so the molecular basis of disease could not be clarified completely
Both parents had offspring affected with JEB and displayed subtle enamel pitting of secondary dentition without any sign of skin blistering. The reported enamel abnormality in LAMA3 mutation carriers could be attributed to a half dose effect of the laminin a3 chain
Two of the six genes (LAMA3 and DST (show DST Antibodies)) validated by quantitative RT-PCR for tumor-specific alternative splicing events
LAMNA variants have been identified in atrial fibrillation cohort studies, demonstrating abnormalities in cardiac excitation - supra ventricular tachycardia and atrial fibrillation.
We established the LAMA3 gene as novel potential susceptibility gene for atopic dermatitis.
Expression of a3, beta3 and beta2 cannot predict the prognosis. However, high expression of beta2 mRNA in HCC (show FAM126A Antibodies)/non-cancerous liver correlated significantly with the absence of complete encapsulation, which is an important tumor invasiveness factor.
Results describe a new pedigree identifying a novel mutation of LAMA3 in LOC (show ILK Antibodies) syndrome
A male patient with Herlitz junctional epidermolysis bullosa with a novel homozygosity for insertion LAMA3 Premature Termination Codon mutation is described. Both parents and his sibling were shown to be heterozygous carriers.
High LAMA3 expression is associated with gastric cancer.
tumor cell migration on laminin-5 is inhibited by HYD1 (show MSX1 Antibodies), a biologically active integrin-targeting peptide
Deletion of the Lama3 gene leads to abnormnal development of glomerular endothelial and mesangial cells.
Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
laminin, alpha 3
, laminin alpha 3 subunit
, alpha3A chain laminin
, laminin subunit alpha-3-like
, BM600 150kD subunit
, epiligrin 170 kda subunit
, epiligrin alpha 3 subunit
, epiligrin subunit alpha
, kalinin 165kD subunit
, kalinin subunit alpha
, laminin subunit alpha-3
, laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)
, laminin-5 alpha 3 chain
, laminin-5 subunit alpha
, laminin-6 subunit alpha
, laminin-7 subunit alpha
, nicein 150kD subunit
, nicein subunit alpha
, nicein, 150kDa
, laminin 5 alpha 3