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Laminin, gamma 1 Proteins (LAMC1)

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. Additionally we are shipping Laminin gamma 1 Antibodies (124) and Laminin gamma 1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LAMC1 226519  
LAMC1 117036  
LAMC1 3915 P11047
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Top Laminin gamma 1 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$732.60
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$952.01
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$983.48
Details

LAMC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

More Proteins for Laminin, gamma 1 (LAMC1) Interaction Partners

Mouse (Murine) Laminin, gamma 1 (LAMC1) interaction partners

  1. Analysis of nidogen-1 (show NID1 Proteins) and laminin-gamma1 interaction reveals multiple binding modes.

  2. The C-terminal domains of mouse laminin gamma 1 and nidogen 1 (show NID1 Proteins) mediate interactions complex formation.

  3. STI1 (show STIP1 Proteins) and Ln-gamma1 promote robust axonogenesis in wild-type neurons, whereas no effect is observed in neurons from PrPC (show PRNP Proteins)-null mice.

  4. Data show that expression of either mGluR1 (show GRM1 Proteins) or mGluR5 (show GRM5 Proteins) in HEK293 cells reconstituted the signaling pathways mediated by PrP(C (show PRNP Proteins))-Ln gamma1 peptide interaction.

  5. Laminin beta(1 (show LAMB1 Proteins)) and gamma(1) N-terminal domains share the galactose-binding domain-like fold.

  6. Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.

  7. structure of the interacting domains reveals a six-bladed Tyr (show TYR Proteins)-Trp (show TYRP1 Proteins)-Thr (show TRH Proteins)-Asp (show C3 Proteins) (YWTD) beta-propeller domain in nidogen bound to laminin epidermal-growth-factor (show EGF Proteins)-like (LE) modules III3-5 in laminin (LE3-5)

  8. This study demonstrates (1) that laminin initiates axonal sorting and mediates axon-Schwann cell interactions required for Schwann cell proliferation and differentiation. (2) that laminin provides a PI3-kinase (show PIK3CA Proteins)/Akt (show AKT1 Proteins)-mediated Schwann cell survival signal.

  9. netrin-4 (show NTN4 Proteins) is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms

  10. The role of the laminin gamma1 chain for cardiac muscle differentiation and function using cardiomyocytes derived from embryonic stem cells deficient in the LAMC1 gene, was investigated.

Zebrafish Laminin, gamma 1 (LAMC1) interaction partners

  1. Two zebrafish loci, grumpy (show LAMB1 Proteins) and sleepy, encode laminin beta1 and laminin gamma1, respectively. These genes are required for the formation of the laminin-dependent basement membrane is essential for the differentiation of chordamesoderm to notochord.

Human Laminin, gamma 1 (LAMC1) interaction partners

  1. Case Report: Anti-laminin-gamma 1 pemphigoid in patient with generalized pustular psoriasis and psoriasis vulgaris.

  2. The identification of laminin gamma 1 (LAMC1) and myeloid cell leukemia 1 (MCL1 (show MCL1 Proteins)) as direct targets of miR (show MLXIP Proteins)-22 and miR (show MLXIP Proteins)-29a, respectively, suggested a tumor-suppressive role of these miRNAs.

  3. LAMC1 may contribute to the development and progression of uterine carcinoma, likely through enhancing tumor cell motility and invasion.

  4. Case Report: occurrence of anti-laminin-gamma1 pemphigoid in a case of autosomal recessive congenital ichthyosis (show LBR Proteins).

  5. Laminins 411 and 421 differentially promote tumor cell migration via alpha6beta1 integrin and MCAM (CD146 (show MCAM Proteins)).

  6. Data showed that LAMC1 expression is directly regulated by miR (show MLXIP Proteins)-29s.

  7. carbohydrate moiety (alpha-Gal) on laminin gamma-1 and collagen alpha-1 (VI) chain are possibly common IgE-reactive proteins in the Japanese patients with beef allergy

  8. results demonstrate that mutation in either NID1 (show NID1 Proteins) or LAMC1 disrupts the interaction NID1 (show NID1 Proteins)-LAMC1 complex; findings implicate the extracellular matrix in the pathogenesis of Dandy-Walker spectrum disorders

  9. LAMC1 polymorphism could be a protective factor for SLE.

  10. Genetic polymorphism of LAMC1 gene is associated in the pathogenesis of colorectal cancers.

Laminin gamma 1 (LAMC1) Protein Profile

Protein Summary

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.

Gene names and symbols associated with Laminin, gamma 1 Proteins (LAMC1)

  • laminin gamma-1 chain (Smp_163810)
  • laminin, gamma 1 (lamc1)
  • laminin, gamma 1 (Lamc1)
  • laminin, gamma 1 (formerly LAMB2) (LAMC1)
  • laminin, gamma 1 (formerly LAMB2) (Lamc1)
  • B2e protein
  • LAMB2 protein
  • sly protein

Protein level used designations for Laminin, gamma 1 Proteins (LAMC1)

laminin gamma-1 chain , laminin subunit gamma-1 , S-LAM gamma , S-laminin subunit gamma , laminin B2 chain , laminin-1 subunit gamma , laminin-10 subunit gamma , laminin-11 subunit gamma , laminin-2 subunit gamma , laminin-3 subunit gamma , laminin-4 subunit gamma , laminin-6 subunit gamma , laminin-7 subunit gamma , laminin-8 subunit gamma , laminin-9 subunit gamma , shortstop , shp , sleepy

GENE ID SPECIES
8355738 Schistosoma mansoni
100036631 Xenopus (Silurana) tropicalis
226519 Mus musculus
117036 Rattus norvegicus
286832 Danio rerio
3915 Homo sapiens
100734278 Cavia porcellus
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