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anti-Laminin, gamma 2 (LAMC2) Antibodies

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. Additionally we are shipping LAMC2 Proteins (10) and LAMC2 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAMC2 3918 Q13753
LAMC2 16782  
LAMC2 192362  
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Top anti-LAMC2 Antibodies at

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB LAMC2 Antibody (Center) (ABIN657905) western blot analysis in mouse stomach tissue lysates (35 µg/lane). This demonstrates the LAMC2 antibody detected the LAMC2 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC (p), WB Anti-LAMC2 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated ELISA, IHC (p), WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded BT483 xenograft, using Laminin gamma 2, antibody at 1:250 dilution. WB Image Laminin gamma 2 antibody detects Laminin gamma 2 protein by Western blot analysis. A. 30 µg Raji whole cell lysate/extract B. 30 µg NCI-H929 whole cell lysate/extract 5 % SDS-PAGE Laminin gamma 2 antibody , dilution: 1:1000 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC (fp), WB 100 μL Log in to see 6 to 11 Days
Human Rabbit Un-conjugated WB Western blot analysis of Laminin gamma 2 expression in A431 (A), Raji (B) whole cell lysates. 200 μL Log in to see 9 Days

LAMC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
Mouse (Murine) ,

, , , , ,
Rat (Rattus) ,

Top referenced anti-LAMC2 Antibodies

  1. Mouse (Murine) Polyclonal LAMC2 Primary Antibody for WB - ABIN657905 : Tsubota, Ogawa, Oyanagi, Nagashima, Miyazaki: Expression of laminin gamma2 chain monomer enhances invasive growth of human carcinoma cells in vivo. in International journal of cancer. Journal international du cancer 2010 (PubMed)
    Show all 3 references for ABIN657905

More Antibodies against LAMC2 Interaction Partners

Human Laminin, gamma 2 (LAMC2) interaction partners

  1. Laminin expression depends on Ecad (show CDH1 Antibodies) loss and allows Ecad (show CDH1 Antibodies)-defective gastric cancer cells to survive and invade.

  2. Data suggest that LAMC2 promotes metastasis in lung adenocarcinoma via EMT (show ITK Antibodies) and may be a potential therapeutic target.

  3. LAMC2 is a novel non-small cell lung cancer prognostic factor.

  4. Diagnostic value of p40 (show IL9 Antibodies) and LN332 in metaplastic spindle cell carcinoma of the breast was found to be less than that of routinely used markers (p63 (show RPE65 Antibodies) and cytokeratins). LN332 showed staining in a significant proportion of phyllodes tumours and sarcomas.

  5. The elevated expression of LAMC2 on cancer cells appears to drive tumorigenesis through its interactions with several cell-surface receptors

  6. Molecular expression of MMP-7 (show MMP7 Antibodies), laminin c2 or EGFR (show EGFR Antibodies), and their combinations, may be associated with gastric cancer tumor aggressiveness

  7. Through an unbiased genetic approach involving a combination of QTL mapping and positional cloning, we demonstrate that Col17a1 (show COL17A1 Antibodies) is a strong genetic modifier of the non-Herlitz JEB that develops in Lamc2(jeb) mice

  8. LAMC2 is expressed at a higher level in ectopic endometrium (Ec) from women with endometriosis compared with eutopic endometrium (Eu) from women with endometriosis.

  9. The active site of gamma2pf to the N-terminal epidermal growth factor (show EGF Antibodies)-like repeat.

  10. LAMC2 is a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues.

Mouse (Murine) Laminin, gamma 2 (LAMC2) interaction partners

  1. Data suggest that LAMC2 promotes metastasis in lung adenocarcinoma via EMT (show ITK Antibodies) and may be a potential therapeutic target.

  2. Periostin (show POSTN Antibodies) was associated with laminin gamma2, and this association enhanced the proteolytic cleavage of the laminin gamma2 long form to produce its short form.

  3. short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin, nidogen-1 (show NID1 Antibodies), fibulin-1 (show FBLN1 Antibodies) and fibulin-2 (show FBLN2 Antibodies)

  4. Thymosin beta(4 (show TMSB4X Antibodies)) stimulates Lamc2 production independent of TGF-beta (show TGFB1 Antibodies).

  5. agrin (show AGRN Antibodies) and perlecan (show HSPG2 Antibodies) cluster with laminin-2 to contribute to assembly of aneural AChR clusters that precede neural agrin (show AGRN Antibodies) release as well as affect later NMJ development

  6. Protein production was in excess (show RCC1 Antibodies) of the amount required to form heterotrimeric laminin-332 and was associated with the migrating epithelial sheet, suggesting a potential role in wound healing for monomeric laminin-gamma2.

  7. Laminin gamma2 mediates Wnt5a (show WNT5A Antibodies)-induced invasion of gastric cancer cells.

LAMC2 Antigen Profile

Protein Summary

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain\; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature.

Gene names and symbols associated with LAMC2

  • laminin, gamma 2 (LAMC2) antibody
  • laminin, gamma 2 (Lamc2) antibody
  • AA589349 antibody
  • B2T antibody
  • BM600 antibody
  • CSF antibody
  • EBR2 antibody
  • EBR2A antibody
  • LAMB2T antibody
  • LAMC2 antibody
  • LAMNB2 antibody

Protein level used designations for LAMC2

laminin 5 gamma 2 subunit , laminin subunit gamma-2 , laminin-5 gamma 2 , laminin, gamma 2 , laminin, gamma 2-like , laminin 5 gamma 2 , BM600-100kDa , CSF 140 kDa subunit , cell-scattering factor 140 kDa subunit , epiligrin subunit gamma , kalinin subunit gamma , ladsin 140 kDa subunit , laminin B2t chain , large adhesive scatter factor 140 kDa subunit , nicein subunit gamma , kalinin/nicein/epiligrin 100 kDa subunit , laminin gamma2 chain , laminin-5 subunit gamma , nicein, 100kD , nicein, 100kDa , lamimin, gamma 2

408043 Gallus gallus
442939 Canis lupus familiaris
457571 Pan troglodytes
511043 Bos taurus
715212 Macaca mulatta
100216328 Ovis aries
3918 Homo sapiens
16782 Mus musculus
791245 Equus caballus
192362 Rattus norvegicus
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