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Laminin, gamma 3 Proteins (LAMC3)

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. Additionally we are shipping Laminin, gamma 3 Antibodies (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LAMC3 23928 Q9R0B6
LAMC3 10319 Q9Y6N6
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Top Laminin, gamma 3 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

LAMC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human

More Proteins for Laminin, gamma 3 (LAMC3) Interaction Partners

Mouse (Murine) Laminin, gamma 3 (LAMC3) interaction partners

  1. Deletion of Lamb2 (show LAMB2 Proteins) and Lamc3 genes affects astrocyte migration and spatial patterning in the retina.

  2. a strong impact of laminin beta2 and gamma3 subunits on the expression and function of both aquaporin-4 (show AQP4 Proteins) and Kir4.1 (show KCNJ10 Proteins), two important membrane proteins in Muller cells.

  3. In human but not mouse fetal brain, LAMC3 is enriched in postmitotic cortical plate neurons, localizing primarily to the somatodendritic compartment.

  4. Laminin gamma3 chain, located in murine basement membranes, binds to nidogen

  5. netrin-4 (show NTN4 Proteins) is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms

Human Laminin, gamma 3 (LAMC3) interaction partners

  1. Recessive LAMC3 mutations cause malformations of occipital cortical development.

Laminin, gamma 3 (LAMC3) Protein Profile

Protein Summary

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 3. The gamma 3 chain is most similar to the gamma 1 chain, and contains all the 6 domains expected of the gamma chain. It is a component of laminin 12. The gamma 3 chain is broadly expressed in skin, heart, lung, and the reproductive tracts. In skin, it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration. Gamma 3 is also a prominent element of the apical surface of ciliated epithelial cells of lung, oviduct, epididymis, ductus deferens, and seminiferous tubules. The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells.

Gene names and symbols associated with Laminin, gamma 3 Proteins (LAMC3)

  • laminin gamma 3 (Lamc3)
  • laminin, gamma 3 (LAMC3)
  • AI562206 protein
  • AW240805 protein
  • OCCM protein

Protein level used designations for Laminin, gamma 3 Proteins (LAMC3)

laminin subunit gamma-3 , laminin-12 subunit gamma , laminin-14 subunit gamma , laminin-15 subunit gamma

GENE ID SPECIES
23928 Mus musculus
10319 Homo sapiens
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