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Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) Proteins (LSS)

The protein encoded by LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. Additionally we are shipping LSS Antibodies (34) and LSS Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LSS 16987 Q8BLN5
LSS 4047 P48449
LSS 81681 P48450
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Top LSS Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$1,056.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,139.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,219.52
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LSS Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus) ,

More Proteins for Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS) Interaction Partners

Mouse (Murine) Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS) interaction partners

  1. liver-specific ablation of squalene synthase (show FDFT1 Proteins) inhibits hepatic cholesterol biosynthesis and induces hypolipidemia (show ANGPTL3 Proteins) without increasing significant mortality.

  2. Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha (show NR1H3 Proteins)-mediated improvement of hepatic lipid profile.

Human Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS) interaction partners

  1. Lanosterol synthase gene polymorphisms influence both the salt sensitivity of BP and changes in circulating EO in response to a low salt diet.

  2. There were no significant differences in OSC mRNA expression at various stages of breast cancer, or between tumor and normal mammary cells.

  3. two crystal structures of the human membrane protein OSC: the target protein with an inhibitor that showed cholesterol lowering in vivo opens the way for the structure-based design of new OSC inhibitors

  4. Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha (show NR1H3 Proteins)-mediated improvement of hepatic lipid profile.

LSS Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with LSS

  • lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS)
  • lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (lss)
  • lanosterol synthase (CND02520)
  • lanosterol synthase (Tc00.1047053506825.170)
  • lanosterol synthase (Tc00.1047053508175.70)
  • lanosterol synthase (Tb927.7.5230)
  • lanosterol synthase (NCU01119)
  • lanosterol synthase (LmjF06.0650)
  • lanosterol synthase (CGB_D5080W)
  • lanosterol synthase (Lss)
  • lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (Lss)
  • 2810025N20Rik protein
  • BC029082 protein
  • D10Ertd116e protein
  • NCU01119.1 protein
  • OSC protein
  • Tb07.27E10.490 protein
  • xlss protein

Protein level used designations for LSS

lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) , lanosterol synthase , 2,3-epoxysqualene--lanosterol cyclase , oxidosqualene--lanosterol cyclase , 2,3-epoxysqualene-lanosterol cyclase , hOSC , OSC , oxidosqualene lanosterol cyclase , 2,3-oxidosqualene: lanosterol cyclase

GENE ID SPECIES
474058 Pan troglodytes
709227 Macaca mulatta
733925 Xenopus (Silurana) tropicalis
3257258 Cryptococcus neoformans var. neoformans JEC21
3552260 Trypanosoma cruzi strain CL Brener
3553790 Trypanosoma cruzi strain CL Brener
3658735 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3877205 Neurospora crassa OR74A
5649087 Leishmania major strain Friedlin
10191320 Cryptococcus gattii WM276
100055292 Equus caballus
100083602 Ornithorhynchus anatinus
100558321 Anolis carolinensis
100592843 Nomascus leucogenys
100636608 Amphimedon queenslandica
16987 Mus musculus
795400 Danio rerio
4047 Homo sapiens
615906 Bos taurus
81681 Rattus norvegicus
424037 Gallus gallus
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