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The protein encoded by LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. Additionally we are shipping LSS Kits (20) and LSS Proteins (10) and many more products for this protein.
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analysis of co-existing variants in both F8 and PTGS-1 (show PTGS1 Antibodies) genes in a three-generation pedigree of hemophilia A; the PTGS-1 (show PTGS1 Antibodies) variant was associated with specific functional defects in the arachidonic acid pathway and more severe hemorrhage.
Data suggest expression of PTGS1 (show PTGS1 Antibodies) in colon is significantly correlated with expression of PTGS2 (show PTGS2 Antibodies), PTGES1, PTGER2 (show PTGER2 Antibodies), and PTGER4 (show PTGER4 Antibodies); this study was conducted in individuals at high risk for colon cancer treated with Mediterranean diet versus a Healthy Eating diet for prevention of colon cancer. (PG = prostaglandin; PTGS2 (show PTGS2 Antibodies) = PG-endoperoxide synthase 2; PTGES1 = PGE (show LIPF Antibodies) synthase protein; PTGER2 (show PTGER2 Antibodies) = PGE (show LIPF Antibodies) receptor 2; PTGER4 (show PTGER4 Antibodies) = PGE (show LIPF Antibodies) receptor 4)
Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ Antibodies), lipoxygenase and cyclooxygenase.
Panax quinquefolium saponin attenuated HUVEC apoptosis and improved the dual antiplatelet-mediated reduction of platelet adhesion to injured HUVECs and the underlying mechanisms may be associated with PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and COX (show COX8A Antibodies) pathways.
The interactions of COX (show COX8A Antibodies)-1of rs3842787 and cox-2 (show COX2 Antibodies) of rs20417 were associated with aspirin resistance of stroke.
We provide the first report that pro-angiogenic genes PECAM1 (show PECAM1 Antibodies), PTGS1 (show PTGS1 Antibodies), FGD5 (show FGD5 Antibodies), and MCAM (show MCAM Antibodies) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.
a new neutrophil-activating platelet-derived lipid generated by COX-1 (show COX1 Antibodies) is presented that can activate or prime human neutrophils, suggesting a role in innate immunity and acute inflammation.
Seminal COX-1 (show COX1 Antibodies) is over-expressed in infertile oligoasthenoteratozoospermic (OAT (show OAT Antibodies)) men with varicocele (Vx) compared with fertile men with/without and infertile OAT (show OAT Antibodies) men without Vx being associated with oxidative stress, Vx grade and Vx laterality.
In Indian peptic ulcer hemorrhage patients, those with Cox-1 (show COX1 Antibodies) A842G polymorphisms tended to have less gastric ulcers among those with the A842G/C50T polymorphism.
inverse allosteric regulation likely underlies the ability of PGHS-2 (show PTGS2 Antibodies) to operate at low AA concentrations, when PGHS-1 (show PTGS1 Antibodies) is effectively latent.
liver-specific ablation of squalene synthase (show FDFT1 Antibodies) inhibits hepatic cholesterol biosynthesis and induces hypolipidemia (show ANGPTL3 Antibodies) without increasing significant mortality.
Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha (show NR1H3 Antibodies)-mediated improvement of hepatic lipid profile.
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
PGH synthase 1
, prostaglandin G/H synthase 1
, prostaglandin H2 synthase 1
, 2,3-epoxysqualene--lanosterol cyclase
, 2,3-epoxysqualene-lanosterol cyclase
, lanosterol synthase
, oxidosqualene--lanosterol cyclase
, 2,3-oxidosqualene: lanosterol cyclase
, lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
, oxidosqualene lanosterol cyclase