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Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 Proteins (LAMTOR1)

Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. Additionally we are shipping Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 Antibodies (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LAMTOR1 55004 Q6IAA8
LAMTOR1 66508 Q9CQ22
LAMTOR1 308869 Q6P791
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Top Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,361.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,361.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,365.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,365.00
Details

LAMTOR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 (LAMTOR1) Interaction Partners

Human Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 (LAMTOR1) interaction partners

  1. Data suggest that ablation of p18/LAMTOR1 suppresses starvation-induced cell death by stimulating autophagy through modulation of p27(kip1 (show CDKN1B Proteins)) activity.

  2. LAMTOR1 expression affects the tuning of lysosomal activation that can lead to p53 (show TP53 Proteins)-dependent apoptosis through excessive catabolism.

  3. A p27(kip1 (show CDKN1B Proteins))-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA (show RHOA Proteins) and RhoC (show RHOC Proteins).

  4. MT1-MMP (show MMP14 Proteins)-associated protein p27RF-Rho binds p27(kip1 (show CDKN1B Proteins)) and prevents p27(kip1 (show CDKN1B Proteins)) from binding to RhoA (show RHOA Proteins). [p27RF-Rho]

  5. A complex encoded by the MAPKSP1 (show MAPKSP1 Proteins), ROBLD3 (show LAMTOR2 Proteins), and c11orf59 genes interacts with the Rag GTPases, recruits them to lysosomes, and is essential for mTORC1 activation

  6. Studies in rat and mic (show CDKN2C Proteins)e, identified the rat p18 protein a (show MAP2K1 Proteins)s an (show EPHB2 Proteins) endosomal membrane anchoring protein which interacts with MEK1 scaffold (show MAP2K1 Proteins)p14/ (show EPHB2 Proteins)MP1 and mobilizes them to late endosome.

Mouse (Murine) Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 (LAMTOR1) interaction partners

  1. Data suggest that ablation of p18/LAMTOR1 suppresses starvation-induced cell death by stimulating autophagy through modulation of p27(kip1 (show CDKN1B Proteins)) activity.

  2. Findings suggested that the p18 (show CDKN2C Proteins)-associated pathways, mTORC1 and/or MAPK (show MAPK1 Proteins) pathways, are involved in promoting functional interactions between lysosomes and target organelles to regulate lysosome-mediated catabolic processes.

  3. These results suggest that the p18 (show CDKN2C Proteins)-mTORC1 pathway plays crucial roles in the late stages of lysosomal maturation, potentially in late endosome-lysosome fusion, which is required for processing of various macromolecules.

  4. analysis of interactions between kinase scaffold MP1 (show MAPKSP1 Proteins)/p14 (show PCOLCE Proteins) and its endosomal anchoring protein p18 (show CDKN2C Proteins)

  5. A p27(kip1 (show CDKN1B Proteins))-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA (show RHOA Proteins) and RhoC (show RHOC Proteins).

  6. lipid raft adaptor p18 (show CDKN2C Proteins) is essential for anchoring the MEK (show MDK Proteins)-ERK (show EPHB2 Proteins) pathway to late endosomes, and shed new light on a role of endosomal MEK (show MDK Proteins)-ERK (show EPHB2 Proteins) pathway in controlling endosome dynamics.

Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 1 (LAMTOR1) Protein Profile

Protein Summary

Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation (By similarity).

Gene names and symbols associated with LAMTOR1

  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (LAMTOR1)
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (Lamtor1)
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (lamtor1)
  • 2400001E08Rik protein
  • c11orf59 protein
  • C15H11orf59 protein
  • flj20625 protein
  • p18 protein
  • p27rf-rho protein
  • pdro protein
  • ragulator1 protein

Protein level used designations for LAMTOR1

late endosomal/lysosomal adaptor and MAPK and MTOR activator 1 , p27Kip1-releasing factor from RhoA , p27RF-Rho , ragulator complex protein LAMTOR1 , rhoA activator C11orf59 homolog , RhoA activator C11orf59 , lipid raft adaptor protein p18 , p27kip1 releasing factor from RhoA , protein associated with DRMs and endosomes , ragulator complex protein PDRO , RhoA activator C11orf59 homolog

GENE ID SPECIES
614849 Bos taurus
55004 Homo sapiens
66508 Mus musculus
308869 Rattus norvegicus
379890 Xenopus laevis
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