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The protein encoded by LTBP1 belongs to the family of latent TGF-beta binding proteins (LTBPs). Additionally we are shipping LTBP1 Kits (20) and and many more products for this protein.
Showing 10 out of 35 products:
Human Polyclonal LTBP1 Primary Antibody for IHC (p), WB - ABIN392207
Saraon, Musrap, Cretu, Karagiannis, Batruch, Smith, Drabovich, Trudel, van der Kwast, Morrissey, Jarvi, Diamandis: Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer. in The Journal of biological chemistry 2012
Human Polyclonal LTBP1 Primary Antibody for ELISA, WB - ABIN561694
Kang, Yeom, Kim, Kim, Lee: Expression profiling of more than 3500 proteins of MSS-type colorectal cancer by stable isotope labeling and mass spectrometry. in Journal of proteomics 2012
Significantly higher frequency of TT genotype of transforming growth factor-Beta 1 (show TGFB1 Antibodies) in asthma patients was found compared to controls.
The aim of this study is to evaluate whether specific inhibition of c-Abl (show ABL1 Antibodies) by siRNA can influence the transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies))-induced fibrotic responses.
LTBP-1 showed both an accumulation and a striking co-localization with Notch3 (show NOTCH3 Antibodies)-ECD (show SHFM1 Antibodies) deposits suggesting specific recruitment into aggregates in brain in CADASIL (show NOTCH3 Antibodies).
This review concludes that TGF-beta1 (show TGFB1 Antibodies) 29T/C polymorphism does not play a role in breast cancer susceptibility in overall or ethnicity-specific manner.
LTBP-1 an extracellular matrix protein and key regulator of TGF-beta (show TGFB1 Antibodies) bioavailability is a novel HtrA1 (show HTRA1 Antibodies) target.Attenuation of TGF-beta (show TGFB1 Antibodies) signaling caused by a lack of HtrA1 (show HTRA1 Antibodies)-mediated LTBP-1 processing as mechanism underlying CARASIL (show HTRA1 Antibodies) pathogenesis.
Combination of EGF (show EGF Antibodies) with TGF-beta1 (show TGFB1 Antibodies), but not EGF (show EGF Antibodies) or TGF-beta1 (show TGFB1 Antibodies) alone, caused assembly of cells to a new two-dimensional structure, being characterized by dense aggregates connected by branches of few cells.
There is an increasing anti-cancer protection with increased numbers of alleles associated with higher levels of TGF-beta1 (show TGFB1 Antibodies) and IL-4 (show IL4 Antibodies).
The LTBP1 C-terminus adopts a flexible "knotted rope" structure, which may facilitate cell matrix interactions.
these results suggested that the C allele could increase TGF-beta (show TGFB1 Antibodies) secretion which suppresses antitumour immune responses and may affect the Oral squamous cell carcinoma risk.
Lipocalin-2 (show LCN2 Antibodies) negatively modulates the epithelial-to-mesenchymal transition in hepatocellular carcinoma through the epidermal growth factor (show EGF Antibodies) (TGF-beta1 (show TGFB1 Antibodies))/Lcn2 (show LCN2 Antibodies)/Twist1 (show TWIST1 Antibodies) pathway.
Data show the complete knockout of both isoforms of LTBP-1 leads to defective cardiovascular development and subsequent perinatal lethality supporting the idea that LTBP-1 is essential in the development of the great arteries and cardiac cushions.
Ltbp1 functions in a mechanosensory capacity to establish and maintain mammary gland ductal luminal cell fate, support and detect ductal distension, trigger irreversible involution, and facilitate nipple sphincter function.
a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 Antibodies)/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).
miR (show MLXIP Antibodies)-133a mediates TGF-beta (show TGFB1 Antibodies)-dependent derepression of collagen synthesis in hepatic stellate cells during liver fibrosis.
Induction of both Th17-producing cells and Tregs is caused preferentially by Tregs expressing the latent TGF-beta1 (show TGFB1 Antibodies)/GARP (show LRRC32 Antibodies) complex on their cell surface rather than by secreted latent TGF-beta1 (show TGFB1 Antibodies).
results suggest a role for VEGFA (show VEGFA Antibodies)-driven tumour growth by TGF-beta (show TGFB1 Antibodies) signalling inhibition via paracrine mechanisms in vivo
Study reports that master transcription factors also are responsible for directing the gene targets of TGF-beta (show TGFB1 Antibodies) signaling and thus determine the cell-type-specific effects of TGF-beta (show TGFB1 Antibodies) signaling.
requirement for TGF-beta (show TGFB1 Antibodies) signaling into T cells to achieve peripheral CD8 (show CD8A Antibodies) but not CD4 (show CD4 Antibodies) T-cell tolerance
Ltbp1L is a major regulator of Tgf-beta (show TGFB1 Antibodies) activity during valvulogenesis since its absence results in a perturbed Tgf-beta (show TGFB1 Antibodies) pathway that causes all Ltbp1L(-/-) valvular defects.
Shows that Latent Tgfbeta Binding protein 1 (LTBP1), which is a key extracellular modulator of Tgfbeta (show TGFB1 Antibodies) ligand bioavailability, is coexpressed with Tgfbetas in the early limb bud.
This is the first study to investigate the expression and localization of fibrillin proteins and latent TGF-beta (show TGFB1 Antibodies) binding proteins affecting TGFbeta (show TGFB1 Antibodies) bioavailability in the ovary.
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
latent transforming growth factor beta binding protein 1
, latent TGF-beta binding protein 1
, Latent-transforming growth factor beta-binding protein 1
, latent-transforming growth factor beta-binding protein 1-like
, similar to latent transforming growth factor beta binding protein 2
, latent TGFbeta binding protein
, latent-transforming growth factor beta-binding protein 1
, transforming growth factor beta-1-binding protein 1
, latent TGF beta binding protein
, LanC (bacterial lantibiotic synthetase component C)-like 1
, transforming growth factor beta-1-masking protein large subunit
, transforming growth factor-beta (TGF-beta) masking protein large subunit
, latent transforming growth factor binding protein 1