You are viewing an incomplete version of our website. Please click to reload the website as full version.

Latent Transforming Growth Factor beta Binding Protein 2 Proteins (LTBP2)

The protein encoded by LTBP2 belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. Additionally we are shipping LTBP2 Antibodies (22) and LTBP2 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LTBP2 4053 Q14767
Mouse LTBP2 LTBP2 16997 O08999
Rat LTBP2 LTBP2 59106 O35806
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top LTBP2 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

LTBP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) Interaction Partners

Human Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) interaction partners

  1. LTBP-2 and FGF-2 (show FGF2 Proteins) are co-localized in fibrotic human keloid and hypertrophic scar.

  2. LTBP-2 is a potent inhibitor of FGF-2 (show FGF2 Proteins) that may influence FGF-2 (show FGF2 Proteins) bioactivity during wound repair particularly in fibrotic tissues.

  3. LTBP2 was able to reduce phosphorylation of p65 (show GORASP1 Proteins) at Serine 536, inhibit nuclear localization of active phosphorylated p65 (show GORASP1 Proteins), and impair the p65 (show GORASP1 Proteins) DNA-binding ability. This results in a consequential down-regulation of p65 (show GORASP1 Proteins)-related gene expression.

  4. LTBP-2 is an essential component for the formation of microfibril bundles in ciliary zonules.

  5. perlecan (show HSPG2 Proteins) HS was not essential for latent transforming growth factor-beta-1 (show TGFB1 Proteins) binding protein-2 deposition

  6. Overall the results indicate that LTBP-2 may have a negative regulatory role during elastic fiber assembly, perhaps in displacing elastin (show ELN Proteins) microassemblies from complexes with fibulin-5 (show FBLN5 Proteins) and/or cell surface heparan sulfate proteoglycans.

  7. Increased plasma levels of LTBP2 and/or OPN (show SPP1 Proteins) are present in plasma up to 2 years prior to diagnosis of hepatocellular carcinoma.

  8. Some LTBP2 sequence variations can contribute to the etiology of primary open angle glaucoma (POAG) and pseudoexfoliation (PEX (show PHEX Proteins)) glaucoma syndrome.

  9. No pathogenic variants are identified in the LTBP2 gene in a cohort of patients with primary congenital glaucoma.

  10. LTBP2 mutations were not found in the Turkish GLC3C-linked primary congenital glaucoma (PCG) family or in 94 British CYP1B1 (show CYP1B1 Proteins)-negative PCG cases.

Mouse (Murine) Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) interaction partners

  1. LTBP-2 is an essential component for the formation of microfibril bundles in ciliary zonules.

  2. perlecan (show HSPG2 Proteins) HS was not essential for latent transforming growth factor-beta-1 (show TGFB1 Proteins) binding protein-2 deposition

  3. Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5 (show PCSK5 Proteins)/6A.

  4. These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 regulates targeting of DANCE on suitable microfibrils to form elastic fibers.

Cow (Bovine) Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) interaction partners

  1. These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 regulates targeting of DANCE on suitable microfibrils to form elastic fibers.

  2. This is the first study to investigate the expression and localization of fibrillin proteins and latent TGF-beta (show TGFB1 Proteins) binding proteins affecting TGFbeta (show TGFB1 Proteins) bioavailability in the ovary.

LTBP2 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion.

Gene names and symbols associated with LTBP2

  • latent transforming growth factor beta binding protein 2 (LTBP2)
  • latent transforming growth factor beta binding protein 3 (LTBP3)
  • latent transforming growth factor beta binding protein 2 (LOC100341209)
  • latent transforming growth factor beta binding protein 2 (ltbp2)
  • latent transforming growth factor beta binding protein 2 (Ltbp2)
  • AW208642 protein
  • C14orf141 protein
  • GLC3D protein
  • LTBP2 protein
  • LTBP3 protein
  • MSPKA protein
  • MSTP031 protein
  • WMS3 protein

Protein level used designations for LTBP2

latent transforming growth factor beta binding protein 2 , latent transforming growth factor beta binding protein 3 , latent transforming growth factor-beta binding protein 3 , latent-transforming growth factor beta-binding protein 2-like , LTBP-2 , latent-transforming growth factor beta-binding protein 2 , LTBP-2 like protein , latent-transforming growth factor beta-binding protein 3

GENE ID SPECIES
428888 Gallus gallus
453034 Pan troglodytes
483736 Canis lupus familiaris
490784 Canis lupus familiaris
721941 Macaca mulatta
100030163 Monodelphis domestica
100146561 Equus caballus
100341209 Oryctolagus cuniculus
100440144 Pongo abelii
100554083 Anolis carolinensis
100599330 Nomascus leucogenys
100607057 Nomascus leucogenys
4053 Homo sapiens
16997 Mus musculus
59106 Rattus norvegicus
281905 Bos taurus
532772 Bos taurus
Selected quality suppliers for LTBP2 Proteins (LTBP2)
Did you look for something else?