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anti-Lecithin-Cholesterol Acyltransferase (LCAT) Antibodies

LCAT encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. Additionally we are shipping LCAT Kits (45) and LCAT Proteins (37) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LCAT 16816 P16301
LCAT 24530  
LCAT 3931 P04180
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Top anti-LCAT Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LCAT Antibody Titration: 5.0ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram) using LCAT  Antibody , followed by FITC-conjugated goat-anti-rabbit secondary antibodies. Confocal immunofluorescent analysis with 293 cells using LCAT  Antibody , followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of LCAT Antibody (Center) (ABIN653825) in K562 cell line lysates (35 µg/lane). LCAT (arrow) was detected using the purified polyclonal antibody. LCAT Antibody (Center) (ABIN653825) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB Anti-LCAT antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: U87 Cell Lysate Lane 3: HELA Cell Lysate Lane 4: SMMC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB 500 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

LCAT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LCAT Antibodies

  1. Human Polyclonal LCAT Primary Antibody for FACS, IF - ABIN653825 : Weissglas-Volkov, Aguilar-Salinas, Sinsheimer, Riba, Huertas-Vazquez, Ordoñez-Sánchez, Rodriguez-Guillen, Cantor, Tusie-Luna, Pajukanta: Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. in Circulation. Cardiovascular genetics 2010 (PubMed)
    Show all 3 references for ABIN653825

  2. Cow (Bovine) Polyclonal LCAT Primary Antibody for WB - ABIN2776941 : Calabresi, Pisciotta, Costantin, Frigerio, Eberini, Alessandrini, Arca, Bon, Boscutti, Busnach, Frascà, Gesualdo, Gigante, Lupattelli, Montali, Pizzolitto, Rabbone, Rolleri, Ruotolo, Sampietro, Sessa, Vaudo, Cantafora, Veglia, Calandra, Bertolini, Frances: The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families. in Arteriosclerosis, thrombosis, and vascular biology 2005 (PubMed)
    Show all 2 references for ABIN2776941

  3. Human Polyclonal LCAT Primary Antibody for EIA, FACS - ABIN953145 : McGeachie, Ramoni, Mychaleckyj, Furie, Dreyfuss, Liu, Herrington, Guo, Lima, Post, Rotter, Rich, Sale, Ramoni: Integrative predictive model of coronary artery calcification in atherosclerosis. in Circulation 2009 (PubMed)
    Show all 2 references for ABIN953145

  4. Cow (Bovine) Polyclonal LCAT Primary Antibody for WB - ABIN2776942 : Aranda, Valdivielso, Pisciotta, Garcia, Garcã A-Arias, Bertolini, Martã N-Reyes, Gonzã Lez-Santos, Calandra: Therapeutic management of a new case of LCAT deficiency with a multifactorial long-term approach based on high doses of angiotensin II receptor blockers (ARBs). in Clinical nephrology 2008 (PubMed)

More Antibodies against LCAT Interaction Partners

Mouse (Murine) Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. increased cholesterol esterification by LCAT is atheroprotective

  2. Gene transfer of WT LCAT in LCAT(-/-) mice increased 11.8-fold the plasma cholesterol, whereas the LCAT[T147I] and LCAT[P274S] mutants caused a 5.2- and 2.9-fold increase, respectively.

  3. DYRK1A (show DYRK1A Antibodies) overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I (show APOA1 Antibodies) levels.

  4. adrenal glucocorticoid function in LCAT knockout (KO) mice

  5. a novel function of apoA-IV (show APOA4 Antibodies) in the biogenesis of discrete HDL (show HSD11B1 Antibodies)-A-IV particles with the participation of ABCA1 (show ABCA1 Antibodies) and LCAT

  6. Studies suggest that absence of lecithin cholesterol acyltransferase (LCAT) may protect against insulin (show INS Antibodies) resistance, diabetes and obesity.

  7. Data show that LCAT activity was significantly higher in long chain base biosynthesis protein 2 (Sptlc2 (show SPTLC2 Antibodies))+/- and sphingomyelin synthase 2 (Sms2 (show SGMS2 Antibodies))-/- mice, but markedly lower in ApoE (show APOE Antibodies)-/- and Ldlr (show LDLR Antibodies)-/- mice.

  8. LCAT deficiency confers gender-specific protection against diet-induced obesity and insulin (show INS Antibodies) resistance at least in part through regulation in UPR, white adipose tissue adipogenesis, and brown adipocyte partitioning

  9. Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E (show APOE Antibodies) knockout background in association with a reduction in atherosclerosis

  10. LCAT contributes significantly to the cholesteryl ester (CE) fatty acid pool of apoB (show APOB Antibodies) lipoprotein and is the only source of plasma long chain polyunsaturated CE in LDL receptor (show LDLR Antibodies) and apoE (show APOE Antibodies) knockout mice.

Human Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. Mapping the naturally occurring mutations onto the structure provides insight into how they may affect LCAT enzymatic activity.

  2. Report slightly reduction in LCAT that would probably reflect a delay in reverse cholesterol transport occurring in MetS.

  3. rs5923 polymorphism is not associated with low high-density lipoprotein cholesterol(HDL (show HSD11B1 Antibodies)-C)levels in Iranian population

  4. increased cholesterol esterification by LCAT is atheroprotective

  5. The data indicate that this novel apoA-I (show APOA1 Antibodies) missense is associated with markedly decreased levels of HDL (show HSD11B1 Antibodies) cholesterol and very large alpha-1 HDL (show HSD11B1 Antibodies), as well as decreased serum cellular cholesterol efflux and LCAT activity

  6. A robust all-atom model for LCAT generated by homology modeling

  7. This study investigated how the natural LCAT[T147I] and LCAT[P274S] mutations affect the pathway of biogenesis of high-density lipoproteins.

  8. A synonymous H287H mutation in the coding region of exon 6 of the lecithin cholesterol acyltransferase gene was observed in an individual with HDLC levels of 75 mg/dl.

  9. Cosyntropin testing in an unselected subgroup of 8 ABCA1 (show ABCA1 Antibodies) mutation carriers and 3 LCAT mutation carriers did not reveal differences between carriers and controls.

  10. The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits its toxic effect on cultured neurons.

Pig (Porcine) Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. The 1,434 bp mRNA sequence of porcine LCAT including the full coding region and encoding a protein of 472 amino acids, was obtained.

Rabbit Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. LCAT cholesterol esterification is associated with the increase of ApoE (show APOE Antibodies)/ApoA-I (show APOA1 Antibodies) ratio during atherosclerosis progression in rabbit.

LCAT Antigen Profile

Protein Summary

This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.

Gene names and symbols associated with LCAT

  • lecithin-cholesterol acyltransferase (LCAT) antibody
  • lecithin-cholesterol acyltransferase (lcat) antibody
  • lecithin cholesterol acyltransferase (Lcat) antibody
  • lecithin-cholesterol acyltransferase (Lcat) antibody
  • AI046659 antibody
  • D8Wsu61e antibody
  • LCAT antibody
  • MGC82035 antibody
  • MGC88964 antibody

Protein level used designations for LCAT

lecithin-cholesterol acyltransferase , lecithin cholesterol acyltransferase , phosphatidylcholine-sterol acyltransferase , lecithin-cholesterol acyltransferase Lcat , phospholipid-cholesterol acyltransferase , Lecithin-cholesterol acyltransferase

GENE ID SPECIES
100053753 Equus caballus
114449 Danio rerio
447501 Xenopus laevis
448241 Xenopus (Silurana) tropicalis
743056 Pan troglodytes
100126664 Papio anubis
100389625 Callithrix jacchus
100469078 Ailuropoda melanoleuca
100528492 Ictalurus punctatus
16816 Mus musculus
24530 Rattus norvegicus
3931 Homo sapiens
479680 Canis lupus familiaris
100303723 Sus scrofa
510960 Bos taurus
100008978 Oryctolagus cuniculus
100727686 Cavia porcellus
396136 Gallus gallus
100302343 Ovis aries
Selected quality suppliers for anti-LCAT (LCAT) Antibodies
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