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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping LGALS1 Kits (61) and LGALS1 Proteins (51) and many more products for this protein.
Showing 10 out of 229 products:
Mouse (Murine) Polyclonal LGALS1 Primary Antibody for ELISA (Capture), FACS - ABIN4899423
Silva-Monteiro, Reis Lorenzato, Kenji Nihei, Junqueira, Rabinovich, Hsu, Liu, Savino, Chammas, Villa-Verde: Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. in The American journal of pathology 2007
Show all 9 references for ABIN4899423
Human Polyclonal LGALS1 Primary Antibody for FACS, IHC - ABIN4899422
Yazawa, Geddes-Sweeney, Cedeno-Laurent, Walley, Barthel, Opperman, Liang, Lin, Schatton, Laga, Mihm, Qureshi, Widlund, Murphy, Dimitroff: Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential. in The Journal of investigative dermatology 2015
Show all 5 references for ABIN4899422
Human Monoclonal LGALS1 Primary Antibody for IF, WB - ABIN395058
Pál, Antal, Millinghoffer, Hullám, Pálóczi, Tóth, Gabius, Molnár, Falus, Buzás: A novel galectin-1 and interleukin 2 receptor β haplotype is associated with autoimmune myasthenia gravis. in Journal of neuroimmunology 2010
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Human Polyclonal LGALS1 Primary Antibody for EIA, WB - ABIN952433
Okano, Tsuruta, Yamashita, Takano, Echida, Nitta: Suppression of renal fibrosis by galectin-1 in high glucose-treated renal epithelial cells. in Experimental cell research 2010
Show all 3 references for ABIN952433
Human Polyclonal LGALS1 Primary Antibody for IHC, IHC (p) - ABIN4313208
Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006
Show all 2 references for ABIN4313208
Human Polyclonal LGALS1 Primary Antibody for IF (p), IHC (p) - ABIN718586
Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. in Biology of sex differences 2015
Cow (Bovine) Polyclonal LGALS1 Primary Antibody for IHC, WB - ABIN3071771
Bi, Earl, Jacobs, Baum: Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways. in The Journal of biological chemistry 2008
Tumor-driven, unremitting expression of Satb1 (show SATB1 Antibodies) in activated Zbtb46 (show ZNF340 Antibodies)+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 and IL-6 (show IL6 Antibodies).
Gal-1 does not play a role in the systemic immunosuppressive effect of Mesenchymal stem cells.
Galectin-1 has a role in driving lymphoma CD20 (show MS4A1 Antibodies) immunotherapy resistance in a mouse model
These findings highlight the importance of the inflammatory micro-environment of mucosal tissues in modulating intestinal epithelial cells susceptibility to the immunoregulatory lectin Gal-1 and its role in epithelial cell homeostasis.
results unveil a dual role of endogenous versus exogenous Gal-1 in the control of autoimmune testis inflammation.
GAL-1 is valuable biomarker of surgical stress after cardiac surgery.
The authors found that exposure of HL-1 (show ASGR1 Antibodies) cardiac cells to Gal-1 reduced the percentage of infection by two different Trypanosoma cruzi strains, Tulahuen (TcVI) and Brazil (TcI (show LXN Antibodies)).
GAL1/pre-B-cell receptor interaction modifies GAL1/glycan affinity and particularly inhibits binding to LacNAc containing epitopes
Data indicate the relevance of the galectin-1 (Gal-1)-glycan axis in sperm function with implications in mammalian reproductive biology.
Galectin-1 accumulates in neurofilamentous lesions in SOD1 (show SOD1 Antibodies)(G93A) mice, as previously reported in humans with amyotrophic lateral sclerosis (
Gal-1-regulated carcinoma-associated fibroblast activation promotes breast cancer cell metastasis by upregulating MMP-9 (show MMP9 Antibodies) expression.
It is a beta-galactose-binding animal lectin and known to be distributed throughout the body.
Our functional analyses of galectin-1 in urinary bladder urothelial carcinoma provided novel insights into the critical role of galectin-1 in tumor progression and invasion. These results revealed that silencing the galectin-1-mediated MAPK (show MAPK1 Antibodies) signaling pathway presented a novel strategy for bladder cancer therapy.
the TLR4 (show TLR4 Antibodies)/Gal-1 signaling pathway regulates lactate-mediated EMT (show ITK Antibodies) processes through the activation of ADAM10 (show ADAM10 Antibodies) and ADAM17 (show ADAM17 Antibodies) in colon cancer cells.
These findings suggest that Gal-1 plays an important role in immune escape of gingival squamous cell carcinoma cells, and Gal-1 expression level may be a useful clinicopathological prognostic marker for this cancer.
Galectin-1 gene silencing would improve the sensitivity of A549/DDP (show TIMM8A Antibodies) cells to cisplatin in vivo and in vitro.
In this study, gal-1, -2, -3 and -13 were investigated systematically in the trophoblast and decidua compartment of intrauterine growth restriction (IUGR) placentas and normal third trimester control placentas and stratified by fetal gender and gestational age. Gal-1 Expression Shows No Significant Changes in IUGR Placentas in Villous Trophoblasts.
Galectin-1 overexpression activates the FAK (show PTK2 Antibodies)/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway by upregulating expression of alphavbeta3 integrin, leading to enhanced hepatocellular carcinoma invasion via epithelial-mesenchymal transition and sorafenib resistance.
results show that HELLP syndrome is associated with increased circulating levels of gal-1
The integrative analysis of galectins(Gal-1, -3, -4, -9) discriminated IBD from other intestinal inflammatory conditions and could be used as potential mucosal biomarker
Data suggest that galectin-1 and VEGFR-2 (show KDR Antibodies) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (show KDR Antibodies) in luteal cells.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1, LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 (show LGALS9 Antibodies) mRNA would display a differential expression pattern in the endometrium.
The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.
Gal-1 may serve as an adhesion molecule (show NCAM1 Antibodies) to interact with both cells and laminins
Gal-1 is expressed in a wide range of porcine tissues, including striated (show NSDHL Antibodies) muscle, liver, lung, brain, kidney, spleen, and intestine
LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
lectin, galactoside-binding, soluble, 1
, galectin 1
, lectin, galactoside-binding, soluble, 1 (galectin 1)
, 14 kDa lectin
, 14K beta-galactoside-binding lectin
, beta-galactoside-binding lectin
, galectin CG-1B
, Beta-galactoside-binding lectin L-14-I
, Lactose-binding lectin 1
, Lectin galactoside-binding soluble 1
, S-Lac lectin 1
, beta-galactoside binding protein
, beta-galactoside-binding lectin L-14-I
, lactose-binding lectin 1
, lectin galactoside-binding soluble 1
, 14 kDa laminin-binding protein
, beta-galactoside-binding protein 14kDa
, putative MAPK-activating protein PM12
, RL 14.5
, lectin, galactose binding, soluble 1