You are viewing an incomplete version of our website. Please click to reload the website as full version.

Lectin, Galactoside-Binding, Soluble, 8 Proteins (LGALS8)

LGALS8 encodes a member of the galectin family. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 8 Antibodies (87) and Lectin, Galactoside-Binding, Soluble, 8 Kits (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LGALS8 56048 Q9JL15
LGALS8 3964 O00214
LGALS8 116641  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Lectin, Galactoside-Binding, Soluble, 8 Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Rat GST tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$739.20
Details

LGALS8 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus) ,
, ,

Top referenced Lectin, Galactoside-Binding, Soluble, 8 Proteins

  1. Mouse (Murine) LGALS8 Protein expressed in Escherichia coli (E. coli) - ABIN1098433 : Kobayashi, Kuroda, Ashihara, Oomizu, Terui, Taniyama, Adachi, Takagi, Yamamoto, Sasaki, Horiike, Hatake, Yamauchi, Hirashima, Taniwaki: Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways. in Leukemia 2010 (PubMed)
    Show all 2 references for ABIN1098433

  2. Human LGALS8 Protein expressed in Wheat germ - ABIN1309342 : Mao, Ladd, Gad, Rastetter, Johnson, Marzbani, Childs, Lu, Dang, Broussard, Stanton, Hanash, Disis: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer. in Journal of translational medicine 2014 (PubMed)

  3. Rat (Rattus) LGALS8 Protein expressed in Escherichia coli (E. coli) - ABIN2009348 : Bidon-Wagner, Le Pennec: Human galectin-8 isoforms and cancer. in Glycoconjugate journal 2004 (PubMed)

More Proteins for Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) interaction partners

  1. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (show VEGFC Proteins), podoplanin (show PDPN Proteins) and integrin pathways plays a key role.

  2. Gal (show GAL Proteins)-8mut was unable to induce T-cell proliferation, but efficiently co-stimulated antigen-specific responses, bothin vitroandin vivo.

  3. Gal-8 emerges as an attractive therapeutic candidate.

  4. Galectin-8 induces RANKL (show TNFSF11 Proteins) expression, osteoclastogenesis, and bone mass reduction in mice.

  5. Gal-8 stimulated naive T cells, but had an antiproliferative effect when these cells were activated.A dose of recombinant Gal-8 administered with a suboptimal Ag dose to DO11.10 mice strengthened weak responses in vivo.

  6. a novel role for Gal-8 in collaboration with Gal-1 (show LGALS1 Proteins) in plasma cell formation, and suggest the possibility of using distinct LacNAc ligands to modulate the function of Gals.

  7. The findings of the present study delineate the differential molecular requirements for Gal-8 activities on T-cells, and suggest a dual activity relying on activation state.

  8. downstream effectors of PI3K, including PKB (show AKT2 Proteins) and p70 S6 kinase (show PRKACB Proteins), in part mediate cell adhesion, spreading, and microspike formation induced by galectin-8

  9. galectin-8 is expressed in the thymus in mouse, which suggests an active role for this lectin in shaping the mature T cell repertoire

  10. Taken together, our findings support a distinctive role for locally produced Gal-8 as an enhancer of otherwise borderline immune responses and also suggest that Gal-8 might fuel the reactivity at inflammatory foci.

Human Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) interaction partners

  1. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (show VEGFC Proteins), podoplanin (show PDPN Proteins) and integrin pathways plays a key role.

  2. Platelet-derived factor V/Va is generated following endocytosis of the plasma-derived molecule by the platelet precursor cells, megakaryocytes, via a two receptor system consisting of LRP-1 (show LRP1 Proteins) and an unidentified specific "binding site".

  3. Gal-8 expression is a potential independent unfavorable prognostic indicator for postoperative recurrence of patients with localized pT1 clear cell renal cell carcinoma (show MOK Proteins)

  4. The fundamental roles of galectin-8 in human anaplastic large cell lymphoma

  5. The implications of gal-8 in tumor angiogenesis remain to be further explored, but it is exciting to speculate that modulating gal-8-glycan interactions could be used to block lymphatic-vascular connections vital for metastasis

  6. We integrate here the available information on Gal-8 expression in different tumor types and attempt to elucidate associations of its expression and localization with tumor progression[review]

  7. these results not only confirm the pro-inflammatory role we have already proposed for Gal-8 in other cellular systems but also suggest that this lectin is orchestrating the interaction between leukocytes, platelets and endothelial cells

  8. Whereas Galectin (Gal)-1, -3, and -8 triggered vascular endothelial growth factor (VEGF) release, only Gal-8 induced endostatin secretion.

  9. Focusing on the F19Y change in galectin-8, we study of consequences of a single-site substitution in the carbohydrate recognition domain of this family of cellular effectors.

  10. Data indicate that the binding site in galectin-8 is essential for the recruitment of the autophagy receptor NDP52 (show CALCOCO2 Proteins) to cytosol-exposed Salmonella Typhimurium.

Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Protein Profile

Protein Summary

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with LGALS8

  • lectin, galactoside-binding, soluble, 8 (LGALS8)
  • lectin, galactose binding, soluble 8 (Lgals8)
  • lectin, galactoside-binding, soluble, 8 (Lgals8)
  • lectin, galactoside-binding, soluble, 8 (galectin 8) (lgals8)
  • 1200015E08Rik protein
  • AI326142 protein
  • D13Ertd524e protein
  • Gal-8 protein
  • galectin-8 protein
  • Lgals-8 protein
  • LGALS8 protein
  • PCTA-1 protein
  • PCTA1 protein
  • Po66-CBP protein
  • xgalectin-VIIIa protein

Protein level used designations for LGALS8

lectin, galactoside-binding, soluble, 8 , lectin, galactoside-binding, soluble, 8 (galectin 8) , galectin-8-like , gal-8 , galectin 8 , galectin-8 , galectin-8L , lectin, galactose binding, soluble 5 , galectin-8 variant II , Po66 carbohydrate binding protein , galectin-8g , po66 carbohydrate-binding protein , prostate carcinoma tumor antigen 1 , 30 kDa S-type lectin , RL-30 , lectin, galactose binding, soluble 8 , galectin family xgalectin-VIIIa , xgalectin-VIII

GENE ID SPECIES
710375 Macaca mulatta
743841 Pan troglodytes
100436942 Pongo abelii
100595058 Nomascus leucogenys
56048 Mus musculus
430948 Gallus gallus
3964 Homo sapiens
479193 Canis lupus familiaris
100156193 Sus scrofa
506977 Bos taurus
116641 Rattus norvegicus
100343919 Oryctolagus cuniculus
100733991 Cavia porcellus
101115850 Ovis aries
398442 Xenopus laevis
Selected quality suppliers for Lectin, Galactoside-Binding, Soluble, 8 Proteins (LGALS8)
Did you look for something else?