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LGALS9 was initially thought to represent a pseudogene of galectin 9; however, this transcript has good exon-intron structure and encodes a predicted protein of the same size as and highly similar to galectin 9. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 9 Kits (59) and Lectin, Galactoside-Binding, Soluble, 9 Proteins (33) and many more products for this protein.
Showing 10 out of 169 products:
Mouse (Murine) Monoclonal LGALS9 Primary Antibody for FACS - ABIN2658314
Dunphy, Barcham, Bischof, Young, Nash, Meeusen: Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge. in The Journal of biological chemistry 2002
Show all 6 references for ABIN2658314
Mouse (Murine) Monoclonal LGALS9 Primary Antibody for FACS - ABIN2657895
Tsuboi, Abe, Nakagawa, Oomizu, Watanabe, Nishi, Nakamura, Yamauchi, Hirashima: Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes. in Clinical immunology (Orlando, Fla.) 2007
Show all 6 references for ABIN2657895
Human Monoclonal LGALS9 Primary Antibody for ELISA (Capture), FACS - ABIN1449219
Yanai, Saito, Kakinuma, Kon, Hirota, Taniguchi-Yanai, Nishijo, Shigematsu, Horiguchi, Kasuya, Sugiyama, Yagami, Murakami, Fukamizu: Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice. in The Journal of biological chemistry 2000
Show all 5 references for ABIN1449219
Human Polyclonal LGALS9 Primary Antibody for EIA, WB - ABIN952439
Dardalhon, Anderson, Karman, Apetoh, Chandwaskar, Lee, Cornejo, Nishi, Yamauchi, Quintana, Sobel, Hirashima, Kuchroo: Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. in Journal of immunology (Baltimore, Md. : 1950) 2010
Show all 5 references for ABIN952439
Human Monoclonal LGALS9 Primary Antibody for FACS - ABIN1449220
Lipkowitz, Leal-Pinto, Cohen, Abramson: Galectin 9 is the sugar-regulated urate transporter/channel UAT. in Glycoconjugate journal 2004
Show all 3 references for ABIN1449220
Human Polyclonal LGALS9 Primary Antibody for ELISA, WB - ABIN561667
Bellac, Coimbra, Simon, Imboden, Leib: Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. in Neurobiology of disease 2007
Show all 2 references for ABIN561667
Cow (Bovine) Polyclonal LGALS9 Primary Antibody for WB - ABIN2785903
Bi, Earl, Jacobs, Baum: Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways. in The Journal of biological chemistry 2008
The Gal-9/Tim-3 (show HAVCR2 Antibodies) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.
These results indicate the possibility that cooperative binding of oligosaccharide and neighboring polypeptide structures of monoclonal IgE to galectin-9 affects the overall affinity and specificity of the IgE-lectin interaction.
galectin-9 functions as a novel alarmin by augmenting the inflammatory response in sepsis development during pulmonary F. novicida infection.
Gal-9 has a role in the maintenance of hepatic homeostasis and preventing liver ischemia-reperfusion injury
Gal-9, a natural TIM-3 (show HAVCR2 Antibodies) ligand, was produced primarily by and released from ischemia-reperfusion-stressed hepatocytes, both in vivo and in vitro.
Galectin-9 functions as an astrocyte-microglia communication signal and promotes cytokine production from microglia in a Tim-3 (show HAVCR2 Antibodies) independent manner.
galectin-9, in addition to being an effector molecule for regulatory T cells cells, acts synergistically with TGF-beta (show TGFB1 Antibodies) to enforce iTreg cell differentiation and maintenance.
Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.
action of agonist anti-4-1BB (show TNFRSF9 Antibodies) in suppressing autoimmune and allergic inflammation was completely dependent on Galectin-9 (Gal-9). Gal-9 directly bound to 4-1BB (show TNFRSF9 Antibodies), in a site distinct from the binding site of antibodies and the natural ligand of 4-1BB (show TNFRSF9 Antibodies)
Tim-3 (show HAVCR2 Antibodies)/galectin-9 pathway plays a critical role in the homeostasis of hepatic Tregs through the elimination induction in Teffs and the inhibition of IFN-gamma (show IFNG Antibodies) release.
Gal-9 suppressed T-helper 17 (Th17) and expanded regulatory T cells (Tregs), resulting in decreased IL-17 (show IL17A Antibodies) production and increased secretion of TGF-beta1 (show TGFB1 Antibodies)
an abnormal Tim-3 (show HAVCR2 Antibodies)/Gal-9 pathway was able to facilitate the development of preeclampsia.
Galectin-9 stimulated migration in human NK-92 cells by affecting F-actin polarization through the Rho/ROCK1 (show ROCK1 Antibodies) signaling pathway.
may contribute to elevated galectin-9 and adaptive immune inhibition in hepatitis C virus infection
LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
TIM-3 (show HAVCR2 Antibodies) and its ligand, galectin-9 (Gal-9), constitute an autocrine loop critical for leukemic stem cells self-renewal and development of human acute myeloid leukemia (show BCL11A Antibodies).
Galectin-9 is involved in the pathogenesis of autoimmune thyroid disease.Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells.
Study found that LGALS9 was expressed in 68.4% of the human gastrointestinal stromal tumors (GIST) and Tim-3 (show HAVCR2 Antibodies) in the infiltrated NK cells of 68.4% of GISTs and suggest that Tim-3 (show HAVCR2 Antibodies)/LGALS9 pathway may be involved in the immune checkpoint mechanism of GISTs.
We also observed that the Gal-9/miR (show MLXIP Antibodies)-22 axis may influence lymphocyte apoptosis and tumor cell proliferation. These studies contribute to a further understanding of the microRNAmediated regulation of the Gal-9 pathway .
The Tim-3 (show HAVCR2 Antibodies)/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1 (show LGALS1 Antibodies), LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 mRNA would display a differential expression pattern in the endometrium.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
lectin, galactoside-binding, soluble, 9
, galactoside-binding soluble lectin 9
, galectin 9
, lectin, galactoside-binding, soluble, 9 (galectin 9)
, lectin, galactose binding, soluble 5
, tumor antigen HOM-HD-21
, urate transporter/channel protein
, 36 kDa beta-galactoside-binding lectin
, Lectin galactose binding soluble 9 (Galectin-9)
, Lectin, galactose binding, soluble 9 (Galectin-9)
, urate transporter/channel
, urate transporter
, urate transporter/channel protein, isoform (UATp,i)