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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 4 Antibodies (101) and Lectin, Galactoside-Binding, Soluble, 4 Kits (48) and many more products for this protein.
Showing 10 out of 29 products:
Xgalectin-VIa possesses different features from other cement gland genes and is a novel and useful marker of the cement gland in developing embryos.
patterns of galectin-4 and galectin-6 expression in the normal and the dextran sodium sulfate (DSS (show PMP22 Proteins))-damaged digestive
structure of galectin-4 and binding properties of the N-terminal domain carbohydrate-recognition domain (CRD)1 were further investigated and the crystal structure of CRD1 in complex with lactose was determined at 2.1 A resolution
The galectin-4-mediated stimulation of CD4 (show CD4 Proteins)(+) T cells is shown to exacerbate chronic colitis and delay the recovery from acute intestinal injury
While the CRD2 domain of galectin-4 has a high specificity and affinity for A type-2 alpha-GalNAc structures, the CRD1 domain has a broader specificity in correlation to the total binding profile.
X-ray analysis of the N-terminal domain of colon cancer marker Gal-4 is revealed in complex with lactose (the basic building block of known galectin-4 carbohydrate ligands).
galectin-4 plays a unique role in the intestine and assign a novel role of this protein in controlling intestinal inflammation by a selective induction of T cell apoptosis and cell cycle restriction
LGALS4 may function as a tumor suppressor gene in UC progression. Findings provide evidence that methylation-mediated LGALS4 gene repression may be involved in urothelial tumor progression.
Together, the data demonstrated that surface-bound galectin-4 is a dual function protein-down-regulating cell proliferation and chemokine (show CCL1 Proteins) secretion in galectin-4-expressing colorectal cancer cells on one hand and inducing apoptosis in galectin-4-negative colorectal cancer cells on the other hand.
It is a beta-galactose-binding animal lectin and known to be distributed throughout the body.
The integrative analysis of galectins(Gal-1 (show LGALS1 Proteins), -3, -4, -9) discriminated IBD from other intestinal inflammatory conditions and could be used as potential mucosal biomarker
Galectin-1 (show LGALS1 Proteins) was undetectable in normal and ulcerative colitis colonic epithelium, while galectin-2 (show LGALS2 Proteins), galectin-3 (show LGALS3 Proteins), and galectin-4 were strongly expressed.
The data suggests that arm-Gal4 has detrimental effects on Drosophila development and lifespan that are directly dependent upon parental inheritance
The co-expression of galectin-4 and CNT3 (show SLC28A3 Proteins) proteins is not impaired in inflamed colon from patients with Crohn's disease, thereby anticipating the integrity of this system for drug targeting.
Structural characterization of human galectin 4 C-terminal domain in terms its ligands binding specificity has been reported.
some galectins, particularly galectin-3 and -4, showed the ability to drive clathrin-independent mechanisms of endocytosis.
The results show galectin-4 expression closely associates with hepatocellular carcinoma (HCC (show FAM126A Proteins)) progression and might have potential use as a prognostic biomarker for HCC (show FAM126A Proteins) patients.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer.
lectin, galactoside-binding, soluble, 4
, lectin, galactoside-binding, soluble, 4 (galectin 4)
, galectin family xgalectin-VIa
, lactose-binding lectin 4
, L-36 lactose binding protein
, L-36 lactose-binding protein
, Lectin galactose binding soluble 4 (Galectin-4)
, Lectin, galactose binding, soluble 4 (Galectin-4)
, antigen NY-CO-27
, galectin 4