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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping LGALS7 Proteins (11) and LGALS7 Kits (4) and many more products for this protein.
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Human Polyclonal LGALS7 Primary Antibody for WB - ABIN1881493
Demers, Rose, Grosset, Biron-Pain, Gaboury, Siegel, St-Pierre: Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells. in The American journal of pathology 2010
Show all 4 references for ABIN1881493
results indicate that an excess of galectin-7 leads to a destabilisation of adherens junctions associated with defects in epidermal repair
Overexpression of galectin-7 increased the resistance of melanoma cells to apoptosis while inducing de novo egr-1 (show EGR1 Antibodies) expression.
In cardiac transplantation galectin-7 relates to acute allograft rejection and T-cell responses possibly as an accelerant.
Extracellular superoxide dismutase (show SOD3 Antibodies) plays a role not only as a reactive oxygen species scavenger, but also as a pro-apoptotic factor via COX-2 (show COX2 Antibodies)/galectin-7 pathways in the epidermis.
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
Data show that high levels of galectin-7 expression in breast cancer cells drastically increased their ability to metastasize to lungs and bones, and were restricted to high-grade breast carcinomas.
Galectin-3 (show LGALS3 Antibodies) and galectin-7 play a role in corneal epithelial wound healing.
Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype.
Galectin-7 promotes maliganacy by upregulating MMP-9 (show MMP9 Antibodies) gene expression.
It is a beta-galactose-binding animal lectin and known to be distributed throughout the body.
Data indicate that the galectin inhibitor specifically binds galectin-7 (hGal (show GCET2 Antibodies)-7), disrupts the formation of homodimers, and inhibits the pro-apoptotic activity of hGal (show GCET2 Antibodies)-7 on Jurkat T cells.
Galectin-7 regulates keratinocytes proliferation and differentiation through JNK1 (show MAPK8 Antibodies) pathway.
The assessment of a carbohydrate-recognition domain (CRD (show CRX Antibodies))-defective mutant form of gal-7 (R7S) showed that the ability of this protein to modulate apoptosis was independent of its CRD (show CRX Antibodies) activity.
our study validates the clinical significance of gal-7 overexpression in ovarian cancer
Cytosolic galectin-7 impairs p53 (show TP53 Antibodies) functions and induces chemoresistance in breast cancer cells.
Galectin-7 is produced by the premenstrual and menstrual endometrium, where it accumulates in menstrual fluid and likely acts as a paracrine factor to facilitate post-menstrual endometrial re-epithelialization.
Understanding how these dendrimeric compounds interact with hGal (show GCET2 Antibodies)-7 would help in the design of new tools to investigate the recognition of carbohydrates by lectins.
galectin-7 is a potential predictive marker of chemotherapy and/or radiotherapy resistance in patients with oral squamous cell carcinoma
Results suggest that galectin-3 (show LGALS3 Antibodies), -4, -7 and -9 could be involved in the biology of inverted papillomas.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19.
, galectin 7
, lectin, galactose binding, soluble 7