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anti-Left-Right Determination Factor 1 (LEFTY1) Antibodies

LEFTY1 encodes a member of the TGF-beta family of proteins. Additionally we are shipping Left-Right Determination Factor 1 Kits (17) and Left-Right Determination Factor 1 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LEFTY1 13590 Q64280
LEFTY1 498299  
LEFTY1 10637 O75610
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Top anti-Left-Right Determination Factor 1 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LEFTY1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with LEFTB antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-LEFTB(C-term) Pab in HL60 cell line lysates (35ug/lane). LEFTB(arrow) was detected using the purified Pab (1:60 dilution). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-LEFTB(C-term) Pab (ABIN391463) in HL60 cell line lysates (35 µg/lane). LEFTB(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with LEFTB antibody (C-term) (ABIN391463), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB LEFTY1 monoclonal antibody (M03), clone 2E10 Western Blot analysis of LEFTY1 expression in THP-1 . LEFTY1 monoclonal antibody (M03), clone 2E10. Western Blot analysis of LEFTY1 expression in C32 . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.66 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

LEFTY1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Left-Right Determination Factor 1 Antibodies

  1. Human Polyclonal LEFTY1 Primary Antibody for EIA, IHC (p) - ABIN359553 : Kosaki, Bassi, Kosaki, Lewin, Belmont, Schauer, Casey: Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. in American journal of human genetics 1999 (PubMed)
    Show all 3 references for ABIN359553

  2. Human Polyclonal LEFTY1 Primary Antibody for WB - ABIN2784907 : Dvash, Sharon, Yanuka, Benvenisty: Molecular analysis of LEFTY-expressing cells in early human embryoid bodies. in Stem cells (Dayton, Ohio) 2007 (PubMed)

  3. Human Monoclonal LEFTY1 Primary Antibody for ELISA, WB - ABIN564640 : Yamasaki, Kasai, Toi, Kurita, Kimoto, Hayata-Takano, Nakazawa, Nagayasu, Shintani, Hashimoto, Ito, Meltzer, Ago, Waschek, Onaka, Matsuda, Baba, Hashimoto et al.: Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-? (TGF-?) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic ... in Journal of neurochemistry 2015 (PubMed)

More Antibodies against Left-Right Determination Factor 1 Interaction Partners

Zebrafish Left-Right Determination Factor 1 (LEFTY1) interaction partners

  1. Our data do not support the reaction-diffusion model, but instead, we propose that Nodal activates signaling in a temporal window that is defined by a miR (show MYLIP Antibodies)-430-mediated delay of Lft1/2 translation

  2. results indicate that differential diffusivity is the major determinant of the differences in Nodal/Lefty (show LEFTY2 Antibodies) range and provide biophysical support for reaction-diffusion models of activator/inhibitor-mediated patterning

  3. both Nodal and Bmp independently are required for lefty1 expression to assure unilateral Nodal activation and correct LR patterning

  4. Bmp represses Nodal signaling independently of lefty1 expression and through the activity of a ligand other than Bmp4 (show BMP4 Antibodies).

  5. we find that Cyclops is specifically required for the maintenance of lefty1 and lefty2 (show LEFTY2 Antibodies) transcription

  6. study reports that microRNA-430 (miR (show MYLIP Antibodies)-430) dampens and balances the expression of the transforming growth factor-beta (TGF-beta) Nodal agonist squint and the TGF-beta (show TGFB1 Antibodies) Nodal antagonist lefty (show LEFTY2 Antibodies)

Mouse (Murine) Left-Right Determination Factor 1 (LEFTY1) interaction partners

  1. exogenous lefty1 administered to mice restored the endogenous expression levels of lefty1. The present study demonstrated that lefty1 attenuated renal interstitial injury by inhibiting the Smaddependent TGFb1 (show TGFB1 Antibodies) signaling pathway

  2. Lefty-1 may prevent TGFB1 (show TGFB1 Antibodies)-induced fibroblast-myofibroblast transdifferentiation in part via modulation of Smad3 (show SMAD3 Antibodies), JNK-3 (show MAPK10 Antibodies), and BMP-5 (show BMP5 Antibodies) signaling.

  3. The expression of lefty (show LEFTY2 Antibodies) in RCC (show XRCC1 Antibodies) cells was lower than that in adjacent non-tumor cells, which may result in the overexpression of nodal, thereby promoting the growth of RCC (show XRCC1 Antibodies).

  4. Studies indicate that the pair of Nodal and Lefty (Lefty1 and Lefty2 (show LEFTY2 Antibodies)) has a conserved role in left-right asymmetry.

  5. Taken together, these results suggest that optimal expression of Lefty1 and Lefty2 (show LEFTY2 Antibodies) is critical for the balanced differentiation of mESCs into three germ layers.

  6. Beta-catenin can recrui (show KDM1A Antibodies)t the H3K4me2/1 d (show CTNNB1 Antibodies)emethylase LSD1 to regulate the expression of the tumor suppressor Lefty1 in mouse embryonic stem cells.

  7. Lefty (show LEFTY2 Antibodies) can antagonise TGF-beta1 (show TGFB1 Antibodies) mediated epithelial-mesenchymal transition in renal tubular epithelial cells.

  8. Cerberus (show CER1 Antibodies)-like and Lefty-1 function redundantly to modulate Nodal signaling during gastrulation and regulate patterning of the primitive streak

  9. Regulated expression and spatial distribution of lefty (show LEFTY2 Antibodies) in mouse endometrium confines its biological impact on tissues that undergo remodelling during estrous cycle and pregnancy.

  10. findings show that decidualized differentiation of stroma, which is a prerequisite for embryo implantation, leads to processing of lefty (show LEFTY2 Antibodies) by PC5/6A (show PCSK5 Antibodies)

Human Left-Right Determination Factor 1 (LEFTY1) interaction partners

  1. Lefty1 could regulates the cell cycle via modulating the expressions of P57 (show CDKN1C Antibodies) and cyclin D1 (show CCND1 Antibodies) and then inhibit the decidualization in vitro.

  2. The mRNA levels of LSD1 (show KDM1A Antibodies) and beta-catenin (show CTNNB1 Antibodies) are inversely correlated with the levels of Lefty1 in pancreas and breast tumors.

  3. Reprogrammed cancer cells share the mechanism for expression of Lefty (show LEFTY2 Antibodies) with induced pluripotent cancer cells (iPS (show SLC27A4 Antibodies)), thus contributing to the cancerous transformation of iPS (show SLC27A4 Antibodies) cells.

  4. Data suggest that Lefty (show LEFTY2 Antibodies) is a novel TGF-beta (show TGFB1 Antibodies) target molecule that mediates growth inhibition of pancreatic cancer cells.

  5. Findings suggest that Lefty1 is negatively modulated by miR (show MLXIP Antibodies)-302s in hESCs, which plays an important role in maintaining the balance between pluripotency and germ layer specification.

  6. The expression of Nodal in normal and malignant endometrial cells that lack Lefty (show LEFTY2 Antibodies) strongly supports an important role for this embryonic morphogen (show SHH Antibodies) in the tissue remodelling events that occur across the menstrual cycle and in tumourogenesis.

  7. nodal and the inhibitors of Nodal signaling, lefty (show LEFTY2 Antibodies)-A and lefty (show LEFTY2 Antibodies)-B, are down-regulated very early upon differentiation of human embryonic stem cells

  8. LEFTY (show LEFTY2 Antibodies) proteins, which are known to play a major role during mouse gastrulation, are transiently expressed during human embryonic stem cell differentiation.

Left-Right Determination Factor 1 (LEFTY1) Antigen Profile

Protein Summary

This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Gene names and symbols associated with LEFTY1

  • lefty1 (lft1) antibody
  • signaling molecule lefty1 (lefty1) antibody
  • left-right determination factor 1 (LEFTY1) antibody
  • left right determination factor 1 (Lefty1) antibody
  • AI450052 antibody
  • antivin antibody
  • atv antibody
  • cb73 antibody
  • Ebaf antibody
  • ik:tdsubc_2b12 antibody
  • LEFTB antibody
  • lefty antibody
  • lefty-1 antibody
  • LEFTY1 antibody
  • LEFTYB antibody
  • RGD1561867 antibody
  • Stra3 antibody
  • Tgfb4 antibody
  • xx:tdsubc_2b12 antibody

Protein level used designations for LEFTY1

signaling molecule lefty1 , left-right determination factor 1 , left-right determination, factor B , left-right determination factor 1-like , TGF-beta-4 , protein lefty-1 , stimulated by retinoic acid gene 3 protein , transforming growth factor beta-4 , left-right determination factor B , protein lefty-B

GENE ID SPECIES
30145 Danio rerio
100049252 Oryzias latipes
699924 Macaca mulatta
737178 Pan troglodytes
100408003 Callithrix jacchus
100435934 Pongo abelii
100597378 Nomascus leucogenys
13590 Mus musculus
498299 Rattus norvegicus
10637 Homo sapiens
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