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LMLN encodes a zinc-metallopeptidase. Additionally we are shipping Leishmanolysin-Like (Metallopeptidase M8 Family) Kits (7) and Leishmanolysin-Like (Metallopeptidase M8 Family) Antibodies (4) and many more products for this protein.
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Immunofluorescent detection of human invadolysin in cultured cells reveals the protein to be associated with the surface of lipid droplets.
the Tg(Tff1 (show TFF1 Proteins)-CreERT2;Tff2 (show TFF2 Proteins)-rtTA;Tff3 (show TFF3 Proteins)-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be suitable to genetically model therapeutic intervention during development, tumorigenesis, and other genetically tractable diseases
Splenic TFF2 (show TFF2 Proteins) is released by vagally modulated memory T cells to suppress expansion of myeloid-derived suppressor cells (MDSC) through CXCR4 (show CXCR4 Proteins). TFF2 (show TFF2 Proteins) is important to the anti-inflammatory reflex arc (show NOL3 Proteins) and has an essential role in arresting MDSC proliferation.
hnRNP A1 (show HNRNPA1 Proteins) improves intestinal injury in anti-CD3 (show CD3E Proteins) antibody-induced enteritis mice through the upregulation of TFF2 (show TFF2 Proteins), which regulates apoptosis and enhances epithelial restoration
Overexpressing Tff2 (show TFF2 Proteins) in cultured cells reduced doubling time in vitro and rapidly increased xenograft tumor size in vivo
Epithelial TFF2 (show TFF2 Proteins) is an important endogenous regulator of gut (show GUSB Proteins) mucosal homeostasis that can modulate immune and epithelial compartments.
The Tff2 (show TFF2 Proteins) gene is expressed in the hypothalamus and is regulated by food intake. Knockout mice are leaner (show CACNA1A Proteins) and have reduced fat mass compared to wild-type.
The increased expression of endogenous TFF2 (show TFF2 Proteins) in response to chronic allergic inflammation is insufficient to prevent the progression of airway inflammation and remodeling in a model of chronic allergic airways disease.
TFF2 (show TFF2 Proteins) functions as a regulator of intestinal homeostasis that suppresses Toxoplasma gondii-driven type 1 inflammation.
TFF2 (trefoil factor 2 (show TFF2 Proteins)), an epithelial cell-derived repair molecule, is needed for the control of lung injury caused by the hookworm parasite Nippostrongylus brasiliensis and for type 2 immunity after infection.
results suggest that during retinal cell death periods, requiring a tightly regulated balance between cell survival and cell death, TFF2 (show TFF2 Proteins) acts pro-proliferative and pro-apoptotic at least in developing mouse retinae cultured in vivo
This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described.
, leishmanolysin-like peptidase
, spasmolytic polypeptide
, trefoil factor 2