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anti-Leprecan Like Protein 1 (LEPREL1) Antibodies

LEPREL1 encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. Additionally we are shipping LEPREL1 Kits (4) and LEPREL1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LEPREL1 210530 Q8CG71
LEPREL1 288016 Q4KLM6
LEPREL1 55214 Q8IVL5
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Top anti-LEPREL1 Antibodies at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 3 to 4 Days
$157.06
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using LEPREL1 antibody. 200 μL Log in to see 9 Days
$588.50
Details
Human Rabbit Un-conjugated IHC, WB   200 μL Log in to see 9 to 14 Days
$653.03
Details

LEPREL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Rat (Rattus)


Human ,


More Antibodies against LEPREL1 Interaction Partners

Mouse (Murine) Leprecan Like Protein 1 (LEPREL1) interaction partners

  1. Altered collagen prolyl 3-hydroxylation is caused by loss of P3H2.

  2. prolyl 3-hydroxylation of type IV collagen (show COL4 Antibodies) by P3H2 has an important function preventing maternal platelet aggregation in response to the early developing embryo

  3. P3H2 is responsible for the hydroxylation of collagen IV (show COL4 Antibodies), which has the highest 3-hydroxyproline content of all collagens. It is thus possible that P3H2 mutations may lead to a disease with changes in basement membranes.

  4. Study found that all 3 mouse Leprecan (show LEPRE1 Antibodies) genes Lepre1 (show LEPRE1 Antibodies), leprel1 and leprel2 (show LEPREL2 Antibodies) are expressed in the notochord; additionally, they are expressed in dorsal root ganglia, limb buds, branchial arches, and developing kidneys.

  5. This report characterizes expression of the P3H1 (show LEPRE1 Antibodies), P3H2 and P3H3 (show LEPREL2 Antibodies) genes in embryonic and adult mice.

Human Leprecan Like Protein 1 (LEPREL1) interaction partners

  1. Recessive LEPREL1 mutations should be recognized as part of the differential diagnosis of lens subluxation.

  2. LEPREL1 plays an important role in eye development and homozygous loss-of-function mutation of this gene can cause severely high myopia and early-onset cataract.

  3. mutation in LRPAP1 is associated with high myopia. Further studies are expected to evaluate the pathogenicity of the variants in CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2.

  4. High myopia is caused by a mutation in LEPREL1, encoding prolyl 3-hydroxylase 2.

  5. P3H2 has preferred substrate sequences among the classes of 3Hyp sites in clade A collagen chains

  6. P3H2 is responsible for the hydroxylation of collagen IV (show COL4 Antibodies), which has the highest 3-hydroxyproline content of all collagens. It is thus possible that P3H2 mutations may lead to a disease with changes in basement membranes.

  7. The restriction of silencing in P3H2 to breast carcinomas, and its association with oestrogen-receptor-positive cases, suggests that P3H2 may be a breast-cancer-specific tumour suppressor.

LEPREL1 Antigen Profile

Protein Summary

This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with LEPREL1

  • leprecan-like 1 (Leprel1) antibody
  • leprecan-like 1 (LEPREL1) antibody
  • 4832416N06 antibody
  • AW553532 antibody
  • MCVD antibody
  • MLAT4 antibody
  • P3H2 antibody

Protein level used designations for LEPREL1

leprecan-like protein 1 , myxoid liposarcoma associated protein 4 , prolyl 3-hydroxylase 2 , myxoid liposarcoma-associated protein 4 , prolyl 3-hydroxylase 3

GENE ID SPECIES
210530 Mus musculus
288016 Rattus norvegicus
55214 Homo sapiens
414143 Gallus gallus
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