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LEPREL2 belongs to a family of collagen prolyl hydroxylases required for proper collagen biosynthesis, folding, and assembly (Vranka et al., 2004 [PubMed 15044469]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Leprecan Like Protein 2 Antibodies (31) and many more products for this protein.
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both P3h3- and Sc65 (show LEPREL4 Proteins)-null mice displayed a similar pattern of severe under-hydroxylation of lysines, particularly at cross-linking sites in type I collagen from bone, skin, dentin, cornea, and aorta, revealing a complex evolution and interplay between the proteins forming the machinery of collagen prolyl 3-hydroxylation and lysyl hydroxylation in the ER
Study found that all 3 mouse Leprecan (show LEPRE1 Proteins) genes Lepre1 (show LEPRE1 Proteins), leprel1 (show LEPREL1 Proteins) and leprel2 are expressed in the notochord; additionally, they are expressed in dorsal root ganglia, limb buds, branchial arches, and developing kidneys.
This report characterizes expression of the P3H1 (show LEPRE1 Proteins), P3H2 (show LEPREL1 Proteins) and P3H3 genes in embryonic and adult mice.
LEPREL2 belongs to a family of collagen prolyl hydroxylases required for proper collagen biosynthesis, folding, and assembly (Vranka et al., 2004
gene rich cluster, B
, prolyl 3-hydroxylase 3
, protein B
, leprecan-like protein 2