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anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) Antibodies

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. Additionally we are shipping Leucine Rich Repeat (In FLII) Interacting Protein 1 Proteins (9) and Leucine Rich Repeat (In FLII) Interacting Protein 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LRRFIP1 16978 Q3UZ39
LRRFIP1 9208 Q32MZ4
LRRFIP1 367314 Q66HF9
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Top anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LRRFIP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LRRFIP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: U937 cell lysate Host: Rabbit  Target Name: LRRFIP1  Sample Tissue: Jurkat Whole Cell lysates  Antibody Dilution: 1.0 µg/mL LRRFIP1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of GCF2 on a A431 lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- human GCF2 antibody. Immunofluoresence staining of A431 cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated WB Western blot detection of LRRFIP1 in Raji, C2C12, MCF7 and Jurkat cell lysates using LRRFIP1 antibody (1: 1000 diluted).  Predicted band size: 89 kDa.  Observed band size: 160 kDa 100 μL Log in to see 8 to 9 Days
$392.86
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Lrrfip1  Sample Tissue: Mouse Muscle lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LRRFIP1 in human colon tissue lysate with LRRFIP1 antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to LRRFIP1 on HeLa cell (antibody concentration 10 µg/mL). LRRFIP1 monoclonal antibody (M08), clone 3E1 Western Blot analysis of LRRFIP1 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to LRRFIP1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1 ug/ml] Immunofluorescence of monoclonal antibody to LRRFIP1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details

LRRFIP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Top referenced anti-Leucine Rich Repeat (In FLII) Interacting Protein 1 Antibodies

  1. Human Monoclonal LRRFIP1 Primary Antibody for IF, WB - ABIN968763 : Khachigian, Santiago, Rafty, Chan, Delbridge, Bobik, Collins, Johnson: GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury. in Circulation research 1999 (PubMed)
    Show all 3 references for ABIN968763

  2. Cow (Bovine) Polyclonal LRRFIP1 Primary Antibody for WB - ABIN2780614 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against Leucine Rich Repeat (In FLII) Interacting Protein 1 Interaction Partners

Mouse (Murine) Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) interaction partners

  1. Experiments in nude mice demonstrated better response of LRRFIP1 overexpressing glioblastoma multiforme xenografts to teniposide.

  2. regulates a rapid type I interferon (show IFNA Antibodies) response

  3. LRRFIP1 and its downstream partner beta-catenin (show CTNNB1 Antibodies) constitute another coactivator pathway for IRF3 (show IRF3 Antibodies)-mediated production of type I interferon (show IFNA Antibodies)

Human Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) interaction partners

  1. Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.

  2. High GCF2 (show GCFC2 Antibodies) expression is associated with hepatoma.

  3. Higher baseline LRRFIP1 expression in human glioblastoma multiforme tissue (n=60) is associated with better prognosis upon later treatment with teniposide.

  4. Data indicate that LRRFIP1 knockdown increased resting TNF (show TNF Antibodies) mRNA level altered the ncRNA abundance at the LRRFIP1 binding region.

  5. The FLI (show FLII Antibodies)-interacting domain of LRRFIP1 forms a classic parallel, homodimeric coiled coil with 10 heptad repeats and 22 helical turns.

  6. GCF2/LRRFIP1 plays an important role in colorectal cancer metastasis by regulating RhoA (show RHOA Antibodies)-induced cell adhesion.

  7. LRRFIP1 is phosphorylated in response to immunologic stimuli and it is directed to lysosomal structures.

  8. An association study of 6 of the 63 genes in 4235 cases and 6379 controls showed a putative association with myocardial infarction for COMMD7 (COMM domain-containing protein 7 (show COMMD7 Antibodies)) and a major deviation from the null hypo thesis for LRRFIP1.

  9. GCF2/LRRFIP1 appears to act as a repressor and occupies the -308 site in cells that do not make TNF-alpha (show TNF Antibodies).

  10. Immediately following lipopolysaccharide stimulation, both LRRFIP2 (show LRRFIP2 Antibodies) and Flap-1/LRRFIP1 compete with Fliih (show FLII Antibodies) for interacting with MyD88 (show MYD88 Antibodies) to activate the signaling.

Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) Antigen Profile

Protein Summary

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Gene names and symbols associated with LRRFIP1

  • leucine rich repeat (in FLII) interacting protein 1a (lrrfip1a) antibody
  • leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1) antibody
  • leucine rich repeat (in FLII) interacting protein 1 (Lrrfip1) antibody
  • AU024550 antibody
  • FLAP-1 antibody
  • FLAP1 antibody
  • FLIIAP1 antibody
  • GCF-2 antibody
  • GCF2 antibody
  • hm:zeh1367 antibody
  • HUFI-1 antibody
  • LRRFIP1 antibody
  • TRIP antibody
  • wu:fc06b04 antibody
  • wu:fi15c07 antibody
  • zeh1367 antibody

Protein level used designations for LRRFIP1

leucine rich repeat (in FLII) interacting protein 1 , leucine-rich repeat flightless-interacting protein 1-like , FLAP (FLI LRR associated protein) , FLI-LRR-associated protein 1 , H186 FLAP , LRR FLII-interacting protein 1 , flap-1 , leucine-rich repeat flightless-interacting protein 1 , GC-binding factor 2 , NEDD8-conjugating enzyme , TAR RNA-interacting protein

GENE ID SPECIES
407677 Danio rerio
428996 Gallus gallus
460050 Pan troglodytes
100066467 Equus caballus
100076391 Ornithorhynchus anatinus
100462541 Pongo abelii
16978 Mus musculus
9208 Homo sapiens
367314 Rattus norvegicus
477419 Canis lupus familiaris
616994 Bos taurus
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