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anti-Leucine Rich Repeat Containing 16A (LRRC16A) Antibodies

Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LRRC16A 55604 Q5VZK9
LRRC16A 68732 Q6EDY6
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Top anti-Leucine Rich Repeat Containing 16A Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB LRRC16A Antibody (C-term)  western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the LRRC16A antibody detected the LRRC16A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
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Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
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Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
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Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

LRRC16A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


More Antibodies against Leucine Rich Repeat Containing 16A Interaction Partners

Human Leucine Rich Repeat Containing 16A (LRRC16A) interaction partners

  1. LRRC16A plays a role in adult respiratory distress syndrome pathophysiology by interacting with, and being mediated through, platelets.

  2. shown for the first time that CARMIL/LRRC16A was associated with gout, which could be due to urate transportsome failure

  3. The results also suggest that the ability of CARMIL1 to inhibit CP in cells may be regulated.

  4. Data suggest that CARMIL promotes uncapping by binding to a freely accessible site on Capping protein (CP) bound to a filament barbed end and inducing a change in the conformation of the actin-binding surface of CP.

  5. The two CARMIL isoforms are both important for cell migration, but they have distinct functions.[CARMIL1, CARMIL2]

Mouse (Murine) Leucine Rich Repeat Containing 16A (LRRC16A) interaction partners

  1. Expression of the capping-protein-binding region of CARMIL (also known as LRRC16A) impaired spindle migration and polar body extrusion during oocyte maturation and decreased the density of the cytoplasmic actin mesh

  2. Our data argue that a large pool of freely diffusing, inactive capping protein (CP:V-1) feeds, via CARMIL-driven complex exchange, the formation of weak-capping complexes (CP:CARMIL) at the plasma membrane of protruding edges.

  3. CARMIL leading edge localization depends on a non-canonical PH domain and dimerization.

  4. the isolated CAH3 domain of CARMIL (and presumably the intact molecule as well) possesses the ability to uncap CP-capped actin filaments

Leucine Rich Repeat Containing 16A (LRRC16A) Antigen Profile

Protein Summary

Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).

Gene names and symbols associated with LRRC16A

  • leucine rich repeat containing 16A (LRRC16A) antibody
  • leucine rich repeat containing 16A (Lrrc16a) antibody
  • 1110037D04Rik antibody
  • AI425970 antibody
  • CARMIL antibody
  • CARMIL1 antibody
  • CARMIL1a antibody
  • D130057M20 antibody
  • dJ501N12.1 antibody
  • dJ501N12.5 antibody
  • Lrrc16 antibody

Protein level used designations for LRRC16A

CARMIL homolog , capping protein, Arp2/3, and Myosin-I Linker homolog 1 , leucine rich repeat containing 16 , leucine-rich repeat-containing protein 16A

GENE ID SPECIES
55604 Homo sapiens
68732 Mus musculus
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