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The protein encoded by LRRC6 contains several leucine-rich repeat domains and appears to be involved in the motility of cilia. Additionally we are shipping Leucine Rich Repeat Containing 6 Proteins (8) and many more products for this protein.
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Cow (Bovine) Polyclonal LRRC6 Primary Antibody for WB - ABIN2774056
Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004
Show all 2 references for ABIN2774056
Human Polyclonal LRRC6 Primary Antibody for WB - ABIN2785516
Gunnarsdóttir, Li, Bauchet, Finstermeier, Stoneking: High-throughput sequencing of complete human mtDNA genomes from the Philippines. in Genome research 2011
Show all 2 references for ABIN2785516
Human Polyclonal LRRC6 Primary Antibody for ICC, IF - ABIN4331627
Horani, Ferkol, Shoseyov, Wasserman, Oren, Kerem, Amirav, Cohen-Cymberknoh, Dutcher, Brody, Elpeleg, Kerem: LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects. in PLoS ONE 2013
ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6.
LRRC6 plays a role in dynein arm assembly or trafficking and when mutated leads to primary ciliary dyskinesia with laterality defects.
Loss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesia.
the Reptin (show RUVBL2 Antibodies)-Lrrc6/Seahorse complex is involved in dynein arm formation.
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt (show WNT2 Antibodies) pathways.
the function of seahorse in cilia motility is separable from its function in other cilia-related phenotypes
Our results suggest that outer dynein arms proteins may be transported from the cytoplasm to the cilia by an Lrrc6-dependent mechanism.
Lrrc6 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
The protein encoded by this gene contains several leucine-rich repeat domains and appears to be involved in the motility of cilia. Defects in this gene are a cause of primary ciliary dyskinesia-19 (CILD19). Two transcript variants, one protein-coding and the other not, have been found for this gene.
testis specific leucine rich repeat protein
, protein TILB homolog
, protein tilB homolog
, testis-specific leucine-rich repeat protein
, leucine-rich repeat-containing protein 6
, leucine-rich testis-specific protein
, leucine rich repeat containing 6 (testis)
, leucine-rich repeat-containing 6 like
, leucine-rich repeat-containing 6-like protein
, unm tg238a
, leucine-rich repeat-containing 6 (testis)