Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
LRRC8A encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. Additionally we are shipping LRRC8A Proteins (10) and many more products for this protein.
Showing 10 out of 41 products:
Human Polyclonal LRRC8A Primary Antibody for WB - ABIN1881512
Conley: Genes required for B cell development. in The Journal of clinical investigation 2003
Show all 3 references for ABIN1881512
Chicken Polyclonal LRRC8A Primary Antibody for WB - ABIN2783752
Smits, Kajava: LRRC8 extracellular domain is composed of 17 leucine-rich repeats. in Molecular immunology 2004
Study identified SWELL1 (LRRC8A), a member of a four-transmembrane protein family with unknown function, as essential for hypotonicity-induced iodide influx. SWELL1 is localized to the plasma membrane, and its knockdown dramatically reduces endogenous volume-regulated anion channel currents and regulatory cell volume decrease in various cell types.
Genomic disruption of LRRC8A ablated volume-regulated anion channel (VRAC) currents. Cells with disruption of all five LRRC8 genes required LRRC8A cotransfection with other LRRC8 isoforms to reconstitute VRAC currents.
LRRC8 is required for B cell development.
identified four genes, named TA-LRRP, AD158 (show LRRC8C Antibodies), LRRC5, and FLJ23420, as unknown LRRC8-like genes
Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
leucine-rich repeat-containing protein 8A
, leucine rich repeat containing 8A
, leucine-rich repeat-containing 8