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Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) ELISA Kits

LRRC8A encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. Additionally we are shipping LRRC8A Antibodies (34) and LRRC8A Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LRRC8A LRRC8A 56262 Q8IWT6
Anti-Rat LRRC8A LRRC8A 311846 Q4V8I7
Anti-Mouse LRRC8A LRRC8A 241296 Q80WG5
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More ELISA Kits for LRRC8A Interaction Partners

Human Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) interaction partners

  1. Study identified SWELL1 (LRRC8A), a member of a four-transmembrane protein family with unknown function, as essential for hypotonicity-induced iodide influx. SWELL1 is localized to the plasma membrane, and its knockdown dramatically reduces endogenous volume-regulated anion channel currents and regulatory cell volume decrease in various cell types.

  2. Genomic disruption of LRRC8A ablated volume-regulated anion channel (VRAC) currents. Cells with disruption of all five LRRC8 genes required LRRC8A cotransfection with other LRRC8 isoforms to reconstitute VRAC currents.

  3. LRRC8 is required for B cell development.

  4. identified four genes, named TA-LRRP, AD158 (show LRRC8C ELISA Kits), LRRC5, and FLJ23420, as unknown LRRC8-like genes

Mouse (Murine) Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) interaction partners

  1. Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.

LRRC8A Antigen Profile

Antigen Summary

This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Gene names and symbols associated with LRRC8A

  • leucine rich repeat containing 8 family, member A (lrrc8a) antibody
  • leucine rich repeat containing 8 family, member A (LRRC8A) antibody
  • leucine rich repeat containing 8 family, member A (Lrrc8a) antibody
  • leucine rich repeat containing 8A (Lrrc8a) antibody
  • AGM5 antibody
  • LLRC8A antibody
  • Lrrc8 antibody
  • mKIAA1437 antibody
  • wu:fb18g12 antibody
  • wu:fi21b10 antibody

Protein level used designations for LRRC8A

leucine-rich repeat-containing protein 8A , leucine rich repeat containing 8A , leucine-rich repeat-containing 8

GENE ID SPECIES
327642 Danio rerio
494672 Xenopus laevis
417201 Gallus gallus
56262 Homo sapiens
491309 Canis lupus familiaris
505605 Bos taurus
311846 Rattus norvegicus
241296 Mus musculus
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