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anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) Antibodies

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). Additionally we are shipping LINGO1 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LINGO1 84894 Q96FE5
LINGO1 235402 Q9D1T0
LINGO1 315691  
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Top anti-LINGO1 Antibodies at antibodies-online.com

Showing 10 out of 116 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of LINGO1 Antibody (N-term) (ABIN652312) in mouse cerebellum tissue lysates (35 µg/lane). LINGO1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of LINGO1 (arrow) using rabbit polyclonal LINGO1 Antibody (N-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of LINGO-1(LRRN6A)(ABIN651289) in mouse liver tissue lysates (35 µg/lane).LRRN6A (arrow) was detected using the purified polyclonal antibody. LINGO-1(LRRN6A)-S596 (C-term) Antibody (ABIN651289) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of LINGO1 (arrow) using rabbit polyclonal LINGO1 Antibody (N-term) (ABIN391440).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 Antibody (N-term) (ABIN391440), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho-LINGO-1(LRRN6A)-pS596 Pab (ABIN650826) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-LINGO1 antibody  ABIN1049010 IHC staining of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-LINGO1 antibody  ABIN1049009 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-Lingo-1 Polyclonal Antibody, Unconjugated (ABIN738801) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and rat brain tissue labeled with Anti-Lingo-1 Polyclonal Antibody, unconjugated  (ABIN738801)  at 1: 200 followed by incubation with conjugated secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

LINGO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LINGO1 Antibodies

  1. Human Polyclonal LINGO1 Primary Antibody for EIA, IHC (p) - ABIN359531 : Inoue, Lin, Lee, Shao, Mendes, Snodgrass-Belt, Sweigard, Engber, Pepinsky, Yang, Beal, Mi, Isacson: Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 2 references for ABIN359531

  2. Human Polyclonal LINGO1 Primary Antibody for WB - ABIN652312 : Mosyak, Wood, Dwyer, Buddha, Johnson, Aulabaugh, Zhong, Presman, Benard, Kelleher, Wilhelm, Stahl, Kriz, Gao, Cao, Ling, Pangalos, Walsh, Somers: The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for ABIN652312

  3. Human Polyclonal LINGO1 Primary Antibody for IHC (p), WB - ABIN651289 : Towner, Jensen, Vaillant, Colman, Saunders, Giles, Wren: Experimental validation of 5 in-silico predicted glioma biomarkers. in Neuro-oncology 2013 (PubMed)

More Antibodies against LINGO1 Interaction Partners

Human Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. LINGO1 rs11856808 plays a protective role by decreasing the risk for PD, but not for MSA (show TPO Antibodies), in Chinese population.

  2. LINGO1 protein acts as a gateway protein internalizing into the tumor cells when engaged by antibody and can carry antibody conjugated with drugs to kill Ewing sarcoma cells.

  3. Data indicate that leucine-rich repeat neuronal protein 1 (LINGO-1) is intracellular and competes with Nogo-66 receptor (NgR (show RTN4R Antibodies)) for binding to p75 neurotrophin receptor (p75NTR (show NGFR Antibodies)).

  4. The results of this study show Increased LINGO1 in the cerebellum of essential tremor patients.

  5. Lingo-1 signaling is altered in the schizophrenia brain.

  6. LINGO-1 can directly bind to ErbB2 (show ERBB2 Antibodies), block ErbB2 (show ERBB2 Antibodies) translocation into lipid rafts, and inhibit its phosphorylation.

  7. This review found that several gene variants in the LINGO1 gene may increase the risk of essential tremor.

  8. LINGO1 variants are associated with essential tremor in Chinese Han female patients.

  9. LINGO-1 potentiates neuronal apoptosis, likely by inhibiting WNK3 (show WNK3 Antibodies) kinase activity.

  10. Results of a meta-analysis suggest a relationship between LINGO1 rs11856808 polymorphism and risk of essential tremor (ET) and familial ET, while rs9652490 polymorphism is only associated with the risk for familial ET.

Mouse (Murine) Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. These data provide morphometric and functional evidence of enhancement of remyelination associated with antagonism of LINGO-1

  2. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions

  3. a novel role for LINGO-1 in neural stem cell differentiation to neurons

  4. inhibitory agents of LINGO-1 activity can protect dopaminergic neurons against degeneration

  5. Lingo1 antagonist promotes spinal cord remyelination and axonal integrity in MOG (show MOG Antibodies)-induced experimental autoimmune encephalomyelitis.

LINGO1 Antigen Profile

Protein Summary

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity).

Gene names and symbols associated with LINGO1

  • leucine rich repeat and Ig domain containing 1 (LINGO1) antibody
  • leucine rich repeat and Ig domain containing 1 (lingo1) antibody
  • leucine rich repeat and Ig domain containing 1 (LOC100228050) antibody
  • leucine rich repeat and Ig domain containing 1 (Lingo1) antibody
  • 4930471K13Rik antibody
  • AV148400 antibody
  • DKFZp459P0736 antibody
  • LERN1 antibody
  • LINGO-1 antibody
  • Lrrn6a antibody
  • UNQ201 antibody

Protein level used designations for LINGO1

leucine rich repeat and Ig domain containing 1 , leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , leucine rich repeat neuronal 6A , leucine-rich repeat and immunoglobilin domain-containing protein 1 , leucine-rich repeat and immunoglobulin domain-containing protein 1 , leucine-rich repeat neuronal protein 1 , leucine-rich repeat neuronal protein 6A , leucine-rich repeat neuronal 6A , cLINGO-1

GENE ID SPECIES
453764 Pan troglodytes
100061441 Equus caballus
100101739 Xenopus (Silurana) tropicalis
100171931 Pongo abelii
100228050 Taeniopygia guttata
84894 Homo sapiens
235402 Mus musculus
415344 Gallus gallus
487660 Canis lupus familiaris
100155465 Sus scrofa
520694 Bos taurus
315691 Rattus norvegicus
Selected quality suppliers for anti-LINGO1 (LINGO1) Antibodies
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