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Leucine Rich Repeat and Sterile alpha Motif Containing 1 Proteins (LRSAM1)

LRSAM1 encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Additionally we are shipping LRSAM1 Antibodies (44) and LRSAM1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LRSAM1 90678 Q6UWE0
LRSAM1 227738 Q80ZI6
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Top LRSAM1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LRSAM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) Interaction Partners

Human Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) interaction partners

  1. Plant homeodomain finger protein 23 negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1

  2. disruption of the C-terminal RING domain confers dominant negative properties to LRSAM1

  3. Our data further confirms that LRSAM1 mutations are associated with CMT2 of AD inheritance.

  4. Authors identify LRSAM1 as the E3 ligase responsible for anti-Salmonella autophagy-associated ubiquitination.

  5. homozygous mutation in LRSAM1 was proposed as a strong candidate for the disease in a family with recessive axonal polyneuropathy

  6. LRSAM1 as a component of the antibacterial autophagic response.

  7. LRSAM1 is a strong candidate for the causal gene for the Charcot-Marie-Tooth disease.

  8. Results suggest that RIFLE represents a novel signaling protein that mediates components of the Wnt/wingless signaling pathway and cell adhesion in PC12 cells [RIFLE protein].

  9. Tal (show TALDO1 Proteins) regulates a Tsg101 (show TSG101 Proteins)-associated complex responsible for the sorting of cargo into cytoplasm-containing vesicles that bud at the multivesicular body and at the plasma membrane

  10. Tal (show TALDO1 Proteins) polyubiquitinates lysine residues in the C-terminus of uncomplexed Tsg101 (show TSG101 Proteins), resulting in proteasomal degradation.

Mouse (Murine) Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) interaction partners

  1. TLR4 (show TLR4 Proteins)/NF-kappaB (show NFKB1 Proteins)-responsive microRNAs and their potential target genes: a mouse model of skeletal muscle ischemia-reperfusion injury.

  2. Lrsam1 mutant mice are more sensitive to challenge with acrylamide, a neurotoxic agent that causes axon degeneration, indicating that the axons in the mutant mice are indeed compromised.

LRSAM1 Protein Profile

Protein Summary

This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with LRSAM1

  • leucine rich repeat and sterile alpha motif containing 1 (LRSAM1)
  • leucine rich repeat and sterile alpha motif containing 1 (Lrsam1)
  • CMT2P protein
  • RIFLE protein
  • TAL protein

Protein level used designations for LRSAM1

E3 ubiquitin-protein ligase LRSAM1 , Tsg101-associated ligase , leucine-rich repeat and sterile alpha motif-containing protein 1 , tsg101-associated ligase

GENE ID SPECIES
90678 Homo sapiens
227738 Mus musculus
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