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Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) ELISA Kits

The protein encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. Additionally we are shipping LDOC1 Antibodies (40) and LDOC1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LDOC1 LDOC1 23641 O95751
Anti-Mouse LDOC1 LDOC1 434784 Q7TPY9
Anti-Rat LDOC1 LDOC1 367956  
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More ELISA Kits for LDOC1 Interaction Partners

Human Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) interaction partners

  1. Cigarette smoke-induced promoter methylation may contribute to LDOC1 downregulation, thereby conferring oncogenic features to oral cells.

  2. LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-kappaB (show NFKB1 ELISA Kits) activation in papillary thyroid carcinoma

  3. Silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.

  4. Silencing of BEX1 (show BEX1 ELISA Kits) and LDOC1 by promoter hypermethylation might represent a critical event in the molecular pathogenesis of oral squamous cell carcinoma (OSCC) and the male predominance of OSCC occurrence.

  5. Letter/Case Report: LDOC1/PARP1 (show PARP1 ELISA Kits) are down-regulated in melanoma with repeated in-transit metastases.

  6. The aim of this study was to evaluate the possible differential expression of LDOC1 mRNA in leucocytes of peripheral blood of Down's syndrome subjects. compared with the normal population.

  7. Over expression of LDOC1 may explain the clinical manifestation found in patients with cryptochidism and Digeorge anomaly.

  8. LDOC1 is dramatically down-regulated in mutated chronic lymphocytic leukemia cases compared with unmutated cases, and have identified a new splice variant, LDOC1S

  9. These observations suggest that LDOC1 is a novel regulator of NF-kappaB (show NFKB1 ELISA Kits) that can affect the PMA or TNF-alpha (show TNF ELISA Kits)-mediated pathway to apoptosis through inhibition of NF-kappaB (show NFKB1 ELISA Kits) activation in BxPC3 pancreatic cancer cells.

  10. MZF-1 (show ZFP42 ELISA Kits) was revealed to interact with LDOC1 and enhance the activity of LDOC1 for inducing apoptosis

LDOC1 Antigen Profile

Antigen Summary

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Gene names and symbols associated with LDOC1

  • leucine zipper, down-regulated in cancer 1 (LDOC1) antibody
  • leucine zipper, down-regulated in cancer 1 (LOC100345630) antibody
  • leucine zipper, down-regulated in cancer 1 (Ldoc1) antibody
  • BCUR1 antibody
  • Gm366 antibody
  • LDOC1 antibody
  • Mar7 antibody
  • Mart7 antibody
  • RGD1565644 antibody

Protein level used designations for LDOC1

leucine zipper, down-regulated in cancer 1 , breast cancer, up-regulated 1 , leucine zipper protein down-regulated in cancer cells , protein LDOC1 , Protein LDOC1

GENE ID SPECIES
696902 Macaca mulatta
100345630 Oryctolagus cuniculus
23641 Homo sapiens
616591 Bos taurus
434784 Mus musculus
367956 Rattus norvegicus
492180 Canis lupus familiaris
100969658 Pan paniscus
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