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Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) ELISA Kits

LZTS1 encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. Additionally we are shipping Leucine Zipper, Putative Tumor Suppressor 1 Antibodies (50) and Leucine Zipper, Putative Tumor Suppressor 1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LZTS1 LZTS1 9638 Q99689
Anti-Rat LZTS1 LZTS1 81730 P97577
Anti-Mouse LZTS1 LZTS1 211134 P60853
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More ELISA Kits for Leucine Zipper, Putative Tumor Suppressor 1 Interaction Partners

Human Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) interaction partners

  1. missense variant in the LZTS1 gene was identified in two Ehlers-Danlos syndrome patients in an extended family.

  2. LZTS1 promoter was frequently methylated in IMPC samples.

  3. Compared with the normal hepatocyte cells, LZTS1 expression in hepatocellular carcinoma cells was significantly lower

  4. miR (show MLXIP ELISA Kits)-135b expression inversely correlated with LZTS1 staining intensity and the Cutaneous Squamous Cell Carcinoma grade.

  5. FEZ1 promotes HIV-1 infection in non-neuronal cells via direct binding to the capsid and kinesin-1 to move the virus into the cell nucleus.

  6. Suggest that LZTS1 plays a potential tumor suppressor role in colorectal cancer progression and represents a valuable clinical prognostic marker of this disease.

  7. Lzts1 was significantly downregulated in breast cancer samples and its deregulation was associated with a higher incidence of tumor recurrence, and to a worse overall survival.

  8. miR (show MLXIP ELISA Kits)-214 functions as an onco-miRNA in osteosarcoma, and its oncogenic effects are mediated chiefly through downregulation of LZTS1

  9. SCOC (show SCOC ELISA Kits) forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC (show SCOC ELISA Kits) dimerization and the SCOC (show SCOC ELISA Kits) surface residue R117 are important for this interaction.

  10. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein (show SCOC ELISA Kits)) and kinesins (kinesin heavy chain (show KIF5A ELISA Kits)) are involved in biological transport process.

Mouse (Murine) Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) interaction partners

  1. The results of this study provide a novel Rap2 (show RAP2A ELISA Kits)-specific regulatory mechanism in synaptic maturation involving PSD-Zip70.

  2. Taken together, the spatial and temporal distribution of Lzts1 is consistent with a potential function(s) in cell cycle regulation, axon growth or guidance, and/or migration of neurons.

  3. Lzts1 deficiency was associated with an increased incidence of both spontaneous and carcinogen-induced cancers in mice.

  4. Partial or complete loss of Lzts1 downregulates Cdc25C (show CDC25C ELISA Kits) and inhibits Cdk1 (show CDK1 ELISA Kits) activity during mitosis, leading to premature transition from metaphase to anaphase.

  5. Loss of one or both LZTS1 alleles hampers the normal defenses of urothelial cells against carcinogens, favoring bladder cancer development, which may make FEZ1 (show FEZ1 ELISA Kits) a target for gene therapy.

Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) Antigen Profile

Antigen Summary

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Gene names and symbols associated with LZTS1

  • leucine zipper, putative tumor suppressor 1 (LZTS1) antibody
  • leucine zipper, putative tumor suppressor 1 (lzts1) antibody
  • fasciculation and elongation protein zeta 1 (zygin I) (FEZ1) antibody
  • fasciculation and elongation protein zeta 1 (zygin I) (Fez1) antibody
  • leucine zipper, putative tumor suppressor 1 (Lzts1) antibody
  • F37 antibody
  • FEZ1 antibody
  • LZTS1 antibody
  • Psdzip70 antibody

Protein level used designations for LZTS1

leucine zipper, putative tumor suppressor 1 , leucine zipper putative tumor suppressor 1-like , fasciculation and elongation protein zeta-1 , zygin I , zygin-1 , protein kinase C-binding protein Zeta1 , zygin 1 , F37/Esophageal cancer-related gene-coding leucine-zipper motif , leucine zipper putative tumor suppressor 1 , F37 esophageal cancer-related leucine zipper motif 1 , leucine-zipper protein FEZ1 , PSD-Zip70

GENE ID SPECIES
464034 Pan troglodytes
486136 Canis lupus familiaris
741727 Pan troglodytes
100030407 Monodelphis domestica
100073437 Ornithorhynchus anatinus
100126058 Xenopus (Silurana) tropicalis
100404687 Callithrix jacchus
100484902 Ailuropoda melanoleuca
100549642 Meleagris gallopavo
100552142 Anolis carolinensis
100604452 Nomascus leucogenys
9638 Homo sapiens
81730 Rattus norvegicus
612764 Canis lupus familiaris
511751 Bos taurus
11178 Homo sapiens
539634 Bos taurus
211134 Mus musculus
266711 Rattus norvegicus
431331 Gallus gallus
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