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anti-Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) Antibodies

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Additionally we are shipping LZTS2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LZTS2 84445 Q9BRK4
LZTS2 226154 Q91YU6
LZTS2 365468 Q3LUD4
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Top anti-LZTS2 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LZTS2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB LZTS2 Antibody (C-term) (ABIN656926) western blot analysis in WiDr cell line lysates (35 µg/lane). This demonstrates the LZTS2 antibody detected the LZTS2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LZTS2 Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry of LZTS2 in human kidney tissue with LZTS2 Antibody at 2.5 ug/ml. Western blot analysis of LZTS2 in human kidney tissue lysate with LZTS2 Antibody  at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB LZTS2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

LZTS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
,

, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-LZTS2 Antibodies

  1. Human Polyclonal LZTS2 Primary Antibody for EIA, IHC (p) - ABIN1450155 : Thyssen, Li, Lehmann, Zhuo, Sharma, Sun: LZTS2 is a novel beta-catenin-interacting protein and regulates the nuclear export of beta-catenin. in Molecular and cellular biology 2006 (PubMed)
    Show all 4 references for ABIN1450155

  2. Human Polyclonal LZTS2 Primary Antibody for WB - ABIN656926 : Hyun Hwa Cho, Hye Joon Joo, Ji Sun Song, Yong Chan Bae, Jin Sup Jung: Crossregulation of beta-catenin/Tcf pathway by NF-kappaB is mediated by lzts2 in human adipose tissue-derived mesenchymal stem cells. in Biochimica et biophysica acta 2008 (PubMed)
    Show all 2 references for ABIN656926

More Antibodies against LZTS2 Interaction Partners

Zebrafish Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. Lzts2 regulates gastrula CE movements, dorsoventral patterning, and midline convergence and specification of organ precursors through interaction with and the export of nuclear beta-catenins in zebrafish.

Human Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. LZTS2 could inhibit cell proliferation and cell cycle transition at the G1/S phase and was implicated in the regulation of proteins associated with the canonical Wnt (show WNT2 Antibodies) pathway, including GSK3B (show GSK3b Antibodies) and beta-catenin (show CTNNB1 Antibodies) through inactivating the Akt (show AKT1 Antibodies) pathway.

  2. deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.

  3. LZTS2 is a beta (show SUCLA2 Antibodies)-catenin-interacting protein (show CTNNBIP1 Antibodies) and modulates beta-catenin (show CTNNB1 Antibodies) signaling and localization

  4. The reciprocal crosstalk between beta-catenin (show CTNNB1 Antibodies)/Tcf (show HNF4A Antibodies) pathway and NF-kappaB (show NFKB1 Antibodies) signaling in hMSCs is mediated through the regulation of lzts2 expression.

  5. LAPSER1 C terminal domain inhibits katanin(p80 (show KATNB1 Antibodies)/p60)-mediated microtubule severing in vitro.

Mouse (Murine) Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.

  2. a critical role of LZTS2 in renal development and implicate LZTS2 as a critical regulator of beta-catenin (show CTNNB1 Antibodies)-mediated nephrogenesis.

Xenopus laevis Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. Members of the ProSAP/Shank (show SHANK2 Antibodies) family and LAPSER1 not only play a role in postsynaptic density formation and plasticity, but also during embryonic development.

LZTS2 Antigen Profile

Protein Summary

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin (By similarity).

Gene names and symbols associated with LZTS2

  • leucine zipper, putative tumor suppressor 2 (lzts2) antibody
  • leucine zipper, putative tumor suppressor 2 (LZTS2) antibody
  • leucine zipper, putative tumor suppressor 2 (Lzts2) antibody
  • BC014695 antibody
  • Lapser1 antibody
  • MGC89253 antibody
  • mKIAA1813 antibody
  • si:dkey-250a11.1 antibody

Protein level used designations for LZTS2

leucine zipper putative tumor suppressor 2 homolog , Protein lapser1 , leucine zipper, putative tumor suppressor 2 , leucine zipper putative tumor suppressor 2-like , hLZTS2 , leucine zipper putative tumor suppressor 2 , putative tumor suppressor LAPSER1 , Protein LAPSER1 , protein lapser1

GENE ID SPECIES
448373 Xenopus (Silurana) tropicalis
466256 Pan troglodytes
486846 Canis lupus familiaris
570926 Danio rerio
711279 Macaca mulatta
100060415 Equus caballus
100387418 Callithrix jacchus
100454346 Pongo abelii
84445 Homo sapiens
226154 Mus musculus
365468 Rattus norvegicus
504411 Bos taurus
495421 Xenopus laevis
Selected quality suppliers for anti-LZTS2 (LZTS2) Antibodies
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