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Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) ELISA Kits

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Additionally we are shipping LZTS2 Antibodies (45) and LZTS2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LZTS2 LZTS2 84445 Q9BRK4
Anti-Mouse LZTS2 LZTS2 226154 Q91YU6
Anti-Rat LZTS2 LZTS2 365468 Q3LUD4
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More ELISA Kits for LZTS2 Interaction Partners

Zebrafish Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. Lzts2 regulates gastrula CE movements, dorsoventral patterning, and midline convergence and specification of organ precursors through interaction with and the export of nuclear beta-catenins in zebrafish.

Human Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. LZTS2 could inhibit cell proliferation and cell cycle transition at the G1/S phase and was implicated in the regulation of proteins associated with the canonical Wnt (show WNT2 ELISA Kits) pathway, including GSK3B and beta-catenin (show CTNNB1 ELISA Kits) through inactivating the Akt (show AKT1 ELISA Kits) pathway.

  2. deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.

  3. LZTS2 is a beta (show SUCLA2 ELISA Kits)-catenin-interacting protein (show CTNNBIP1 ELISA Kits) and modulates beta-catenin (show CTNNB1 ELISA Kits) signaling and localization

  4. The reciprocal crosstalk between beta-catenin (show CTNNB1 ELISA Kits)/Tcf (show HNF4A ELISA Kits) pathway and NF-kappaB (show NFKB1 ELISA Kits) signaling in hMSCs is mediated through the regulation of lzts2 expression.

  5. LAPSER1 C terminal domain inhibits katanin(p80 (show KATNB1 ELISA Kits)/p60)-mediated microtubule severing in vitro.

Mouse (Murine) Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.

  2. a critical role of LZTS2 in renal development and implicate LZTS2 as a critical regulator of beta-catenin (show CTNNB1 ELISA Kits)-mediated nephrogenesis.

Xenopus laevis Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. Members of the ProSAP/Shank (show SHANK2 ELISA Kits) family and LAPSER1 not only play a role in postsynaptic density formation and plasticity, but also during embryonic development.

LZTS2 Antigen Profile

Antigen Summary

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin (By similarity).

Gene names and symbols associated with LZTS2

  • leucine zipper, putative tumor suppressor 2 (lzts2) antibody
  • leucine zipper, putative tumor suppressor 2 (LZTS2) antibody
  • leucine zipper, putative tumor suppressor 2 (Lzts2) antibody
  • BC014695 antibody
  • Lapser1 antibody
  • MGC89253 antibody
  • mKIAA1813 antibody
  • si:dkey-250a11.1 antibody

Protein level used designations for LZTS2

leucine zipper putative tumor suppressor 2 homolog , Protein lapser1 , leucine zipper, putative tumor suppressor 2 , leucine zipper putative tumor suppressor 2-like , hLZTS2 , leucine zipper putative tumor suppressor 2 , putative tumor suppressor LAPSER1 , Protein LAPSER1 , protein lapser1

GENE ID SPECIES
448373 Xenopus (Silurana) tropicalis
466256 Pan troglodytes
486846 Canis lupus familiaris
570926 Danio rerio
711279 Macaca mulatta
100060415 Equus caballus
100387418 Callithrix jacchus
100454346 Pongo abelii
84445 Homo sapiens
226154 Mus musculus
365468 Rattus norvegicus
504411 Bos taurus
495421 Xenopus laevis
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