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Leucine Zipper, Putative Tumor Suppressor 2 Proteins (LZTS2)

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Additionally we are shipping LZTS2 Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LZTS2 84445 Q9BRK4
LZTS2 226154 Q91YU6
LZTS2 365468 Q3LUD4
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Top LZTS2 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,947.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LZTS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) Interaction Partners

Zebrafish Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. Lzts2 regulates gastrula CE movements, dorsoventral patterning, and midline convergence and specification of organ precursors through interaction with and the export of nuclear beta-catenins in zebrafish.

Human Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. LZTS2 could inhibit cell proliferation and cell cycle transition at the G1/S phase and was implicated in the regulation of proteins associated with the canonical Wnt (show WNT2 Proteins) pathway, including GSK3B and beta-catenin (show CTNNB1 Proteins) through inactivating the Akt (show AKT1 Proteins) pathway.

  2. deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.

  3. LZTS2 is a beta (show SUCLA2 Proteins)-catenin-interacting protein (show CTNNBIP1 Proteins) and modulates beta-catenin (show CTNNB1 Proteins) signaling and localization

  4. The reciprocal crosstalk between beta-catenin (show CTNNB1 Proteins)/Tcf (show HNF4A Proteins) pathway and NF-kappaB (show NFKB1 Proteins) signaling in hMSCs is mediated through the regulation of lzts2 expression.

  5. LAPSER1 C terminal domain inhibits katanin(p80 (show KATNB1 Proteins)/p60)-mediated microtubule severing in vitro.

Mouse (Murine) Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. deletion of Lzts2 increases susceptibility to spontaneous and carcinogen-induced tumor development.

  2. a critical role of LZTS2 in renal development and implicate LZTS2 as a critical regulator of beta-catenin (show CTNNB1 Proteins)-mediated nephrogenesis.

Xenopus laevis Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) interaction partners

  1. Members of the ProSAP/Shank (show SHANK2 Proteins) family and LAPSER1 not only play a role in postsynaptic density formation and plasticity, but also during embryonic development.

LZTS2 Protein Profile

Protein Summary

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin (By similarity).

Gene names and symbols associated with LZTS2

  • leucine zipper, putative tumor suppressor 2 (lzts2)
  • leucine zipper, putative tumor suppressor 2 (LZTS2)
  • leucine zipper, putative tumor suppressor 2 (Lzts2)
  • BC014695 protein
  • Lapser1 protein
  • MGC89253 protein
  • mKIAA1813 protein
  • si:dkey-250a11.1 protein

Protein level used designations for LZTS2

leucine zipper putative tumor suppressor 2 homolog , Protein lapser1 , leucine zipper, putative tumor suppressor 2 , leucine zipper putative tumor suppressor 2-like , hLZTS2 , leucine zipper putative tumor suppressor 2 , putative tumor suppressor LAPSER1 , Protein LAPSER1 , protein lapser1

GENE ID SPECIES
448373 Xenopus (Silurana) tropicalis
466256 Pan troglodytes
486846 Canis lupus familiaris
570926 Danio rerio
711279 Macaca mulatta
100060415 Equus caballus
100387418 Callithrix jacchus
100454346 Pongo abelii
84445 Homo sapiens
226154 Mus musculus
365468 Rattus norvegicus
504411 Bos taurus
495421 Xenopus laevis
Selected quality suppliers for LZTS2 Proteins (LZTS2)
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