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Leucine-Rich PPR-Motif Containing (LRPPRC) ELISA Kits

LRPPRC encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). Additionally we are shipping LRPPRC Antibodies (34) and LRPPRC Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LRPPRC 10128 P42704
LRPPRC 313867 Q5SGE0
LRPPRC 72416 Q6PB66
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Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
Human 0.119 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days

More ELISA Kits for LRPPRC Interaction Partners

Human Leucine-Rich PPR-Motif Containing (LRPPRC) interaction partners

  1. This is the first study to report hypermethylation of LRPPRC, RAB6C, and ZNF471 in squamous cell carcinoma of the tongue

  2. LRPPRC knock-down in mammalian cells leads to an imbalance between mitochondria-encoded and nuclear-encoded subunits of complex IV

  3. study identifies LRPPRC as an important disease-causing gene in an early-onset, multisystem and neurological mitochondrial disease.

  4. LRPPRC levels were reduced in muscle cells and undetectable in liver from French Canadian Leigh Syndrome patients.

  5. LRPPRC is a transcription factor related to ABCB1 expression and highlight the importance of epigenetic regulation in CML resistance.

  6. Downregulation of LRPPRC expression resulted in the reduced expression of Bcl-2 (show BCL2 ELISA Kits), upregulation of Bax (show BAX ELISA Kits), and cleaved caspase-9 (show CASP9 ELISA Kits) and caspase-3 (show CASP3 ELISA Kits). This induces apoptosis through the mitochondria-mediated pathway in PCa (show FLVCR1 ELISA Kits) cells.

  7. LRPPRC functions as a checkpoint protein that prevents mitochondria from autophagy degradation and impact tumorigenesis.

  8. Tetherin (show BST2 ELISA Kits) binds with the mitochondrion-associated autophagy suppressor LRPPRC and prohibits its association with the autophagy initiation complex.

  9. LRPPRC overexpression is associated with gastric cancer.

  10. Data indicate that C14C10.4/MMA-1 Is the Structural and functional homolog of mammalian LRPPRC.

Mouse (Murine) Leucine-Rich PPR-Motif Containing (LRPPRC) interaction partners

  1. both LRPPRC and SLIRP are required for maintaining mt-mRNA steady-state levels independent of their roles in stabilizing the other partner of the LRPPRC-SLIRP complex.

  2. Ectopic expression of LRPPRC in the mouse liver completely interdicted non-alcoholic fatty liver disease, including inflammation.

  3. LRPPRC deficiency in Leigh syndrome causes an ATP synthase deficiency.

  4. LRPPRC does not directly regulate mtDNA transcription but rather acts as a post-transcriptional regulator of mammalian mtDNA expression.

  5. Heart-specific Lrpprc disruption causes mitochondrial cardiomyopathy with drastic reduction in steady-state mitochondrial mRNA levels. LRPPRC forms an RNA-dependent protein complex needed to maintain a mitochondrial pool of non-translated mRNAs.

  6. These data strongly suggest that LRPPRC is involved in the maturation of cytochrome c (show CYCS ELISA Kits) oxidase (COX (show CPOX ELISA Kits)), and is involved in stabilizing of mitochondrial mRNAs encoding COX (show CPOX ELISA Kits) transcripts.

  7. LRP130 protein remodels mitochondria and stimulates fatty acid oxidation.

  8. Our results demonstrate that LIF (show LIF ELISA Kits) signaling via the gp130/JAK (show JAK3 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) pathway is required for the initiation of the astrogliosis-like reaction of retinal Muller cells after optic nerve injury.

  9. LRP130 may function in stabilizing minisatellite DNA sequences.

  10. These data link LRP130 and PGC-1alpha (show PPARGC1A ELISA Kits) to defective hepatic energy homeostasis in Leigh syndrome French Canadian variant , and reveal a novel regulatory mechanism of glucose homeostasis.

LRPPRC Antigen Profile

Antigen Summary

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.

Gene names and symbols associated with LRPPRC

  • leucine-rich pentatricopeptide repeat containing (LRPPRC) antibody
  • leucine-rich pentatricopeptide repeat containing (Lrpprc) antibody
  • leucine-rich PPR-motif containing (Lrpprc) antibody
  • 3110001K13Rik antibody
  • C76645 antibody
  • CLONE-23970 antibody
  • Gp130 antibody
  • Lrp130 antibody
  • Lrp157 antibody
  • Lsfc antibody

Protein level used designations for LRPPRC

130 kDa leucine-rich protein , LRP 130 , leucine-rich PPR motif-containing protein, mitochondrial , leucine-rich PPR-motif containing , mitochondrial leucine-rich PPR motif-containing protein , leucine rich protein 157 , leucine-rich protein 157 , rLRP157 , leucine rich protein LRP130

10128 Homo sapiens
313867 Rattus norvegicus
72416 Mus musculus
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