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Orphan receptor. Additionally we are shipping LGR5 Antibodies (205) and LGR5 Kits (5) and many more products for this protein.
Showing 4 out of 9 products:
Single-cell transcript profiles reveal multilineage priming in early progenitors derived from Lgr5-expressing intestinal stem cells.
Arrb1 (show ARRB1 Proteins) reduced the chemotherapy-induced Lgr5 stem cell apoptosis by inhibiting endoplasmic reticulum stress-mediated mitochondrial apoptotic signaling.
demonstrates that Lgr5 cells give rise to both anterior and posterior taste buds during development, and are capable of regenerating posterior taste buds after injury induced by glossopharyngeal nerve transection
Lgr5(+) chief cells are involved in maintaining the homeostatic stem cell pool. Define Lgr5(+) chief cells as a major cell-of-origin of gastric cancer.
Stem cell plasticity enables hair regeneration following Lgr5(+) cell loss.
role for Lgr5(+) cancer stem cells in primary and metastatic colon cancer
Data show that both the number and relative position of Paneth cells and Lgr5+ cells are important for fission.
RSPO (show RSPO1 Proteins)-LGR4 (show LGR4 Proteins)/5-ZNRF3 (show ZNRF3 Proteins)/RNF43 (show RNF43 Proteins) module controls metabolic liver zonation and is a hepatic growth/size rheostat during development, homeostasis and regeneration.
adult stem cell marker leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5) is expressed in the mice nasal respiratory epithelium.
Employing Lgr5-lacZ (show GLB1 Proteins) transgenic mice and Lgr5 in situ hybridization, authors found colonic epithelial stem cells (CESC) markedly more radioresistant in vivo than small intestinal crypt base columnar stem cells.
Report the presence of aberrantly located LGR5(+) cells coexpressing epithelial markers in the stromal compartment of women with endometriosis. These cells have a statistically significantly different expression profile in deep-infiltrating endometriosis in comparison with other types of endometriosis, independent of the menstrual cycle phase.
LGR5 signaling in gastric cancer cells.LGR5 crosstalk with FOXO1 (show FOXO1 Proteins) in gastric cancer cells.
High LGR5 expression is associated with osteoarthritis.
The LGR5 primarily functions via the IQGAP1-Rac1 pathway to strengthen cell-cell adhesion in normal adult crypt stem cells and colon cancer cells.
LGR5-expressing fraction of CD54 (show ICAM1 Proteins)+ cells represents gastric cancer CSCs, in which LGR5 is closely associated with stemness and EMT (show ITK Proteins) core genes
clathrin-mediated endocytosis inhibition of the leucine-rich G protein-coupled receptor-5 (show XCR1 Proteins) diminishes cell fitness
The findings indicated that Lgr5 might contribute to the intestinal metaplasia during gastric carcinogenesis.
Endometrial LGR5 is not an endogenous stem cell marker. Instead, LGR5(+) cells appear to be recruited from blood to be part of the stem cell niche at the perivascular microenvironment to activate the endogenous niche.
Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.
leucine-rich repeat-containing G protein-coupled receptor 5
, leucine-rich repeat-containing G-protein coupled receptor 5A
, leucine-rich repeat-containing G-protein coupled receptor 5a
, G protein-coupled receptor 49
, G-protein coupled receptor 49
, follicle expressed hormone
, leucine-rich repeat-containing G-protein coupled receptor 5
, orphan G-protein coupled receptor FEX
, G-protein coupled receptor 67
, G-protein coupled receptor HG38
, orphan G protein-coupled receptor HG38