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Leucyl-tRNA Synthetase 2, Mitochondrial Proteins (LARS2)

LARS2 encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Additionally we are shipping LARS2 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LARS2 23395 Q15031
Rat LARS2 LARS2 363172  
Mouse LARS2 LARS2 102436 Q8VDC0
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

LARS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

More Proteins for Leucyl-tRNA Synthetase 2, Mitochondrial (LARS2) Interaction Partners

Human Leucyl-tRNA Synthetase 2, Mitochondrial (LARS2) interaction partners

  1. analysis of the CP1 domain in human mitochondrial leucyl-tRNA synthetase

  2. Leucyl tRNA synthetase is able to partially rescue defects caused by mutations in non-cognate itochondrial-tRNAs.

  3. Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome.

  4. No evidence to support previous data indicating a role in type 2 diabetes susceptibility in humans with LARS2 single nucleotide polymorphisms

  5. Upregulation of LARS2 is a hallmark of 324A>G mutation. The accumulation of 3243A>G mutation in the brain may have a pathophysiologic role in bipolar disorder and schizophrenia.

  6. In this study, we provide evidence that the LARS2 gene may represent a novel type 2 diabetes susceptibility gene.

  7. There was investigated whether overexpression of human mitochondrial LeuRS suppressed translation and respiratory chain defects associated with the pathogenic A3243G mutation in human cells.

  8. data indicate that inactivation of LARS2 by both genetic and epigenetic mechanisms may be a common and important event in the carcinogenesis of nasopharyngeal carcinoma

LARS2 Protein Profile

Protein Summary

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.

Gene names and symbols associated with LARS2

  • leucyl-tRNA synthetase 2, mitochondrial (LARS2)
  • leucyl-tRNA synthetase 2, mitochondrial (lars2)
  • leucyl-tRNA synthetase 2, mitochondrial (LOC100358356)
  • leucyl-tRNA synthetase 2, mitochondrial (Lars2)
  • leucyl-tRNA synthetase, mitochondrial (Lars2)
  • AI035546 protein
  • Kiaa0028 protein
  • LARS2 protein
  • LEURS protein
  • MGC80460 protein
  • PRLTS4 protein

Protein level used designations for LARS2

leucyl-tRNA synthetase 2, mitochondrial , probable leucyl-tRNA synthetase, mitochondrial , Probable leucyl-tRNA synthetase, mitochondrial , leuRS , leucine--tRNA ligase , probable leucine--tRNA ligase, mitochondrial , probable leucyl-tRNA synthetase, mitochondrial-like , leucine tRNA ligase 2, mitochondrial , leucine tRNA ligase 2, mitocondrial , leucine translase , leucyl-tRNA synthetase, mitochondrial

GENE ID SPECIES
420702 Gallus gallus
443989 Xenopus laevis
476652 Canis lupus familiaris
504609 Bos taurus
714224 Macaca mulatta
739246 Pan troglodytes
100082885 Ornithorhynchus anatinus
100163590 Acyrthosiphon pisum
100174294 Pongo abelii
100358356 Oryctolagus cuniculus
100379697 Xenopus (Silurana) tropicalis
100484574 Ailuropoda melanoleuca
100540484 Meleagris gallopavo
100556212 Anolis carolinensis
23395 Homo sapiens
363172 Rattus norvegicus
102436 Mus musculus
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