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anti-Leukocyte Cell Derived Chemotaxin 1 (LECT1) Antibodies

LECT1 encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. Additionally we are shipping Leukocyte Cell Derived Chemotaxin 1 Kits (13) and Leukocyte Cell Derived Chemotaxin 1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LECT1 11061 O75829
LECT1 16840 Q9Z1F6
LECT1 81512 O70367
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Top anti-Leukocyte Cell Derived Chemotaxin 1 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-LECT1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody (C-term) (ABIN389196), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-LECT1 Antibody (C-term) (ABIN389196) in NCI-H460 cell line lysates (35 µg/lane).LECT1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB LECT1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of LECT1 transfected lysate using anti-LECT1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with LECT1 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of LECT1 expression in transfected 293T cell line by LECT1 MaxPab polyclonal antibody.Lane 1: LECT1 transfected lysate(37.10 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of LECT1 expression in transfected 293T cell line by LECT1 MaxPab polyclonal antibody.Lane 1: LECT1 transfected lysate(36.74 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details

LECT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
,

Mouse (Murine)


Rat (Rattus)


Top referenced anti-Leukocyte Cell Derived Chemotaxin 1 Antibodies

  1. Human Polyclonal LECT1 Primary Antibody for EIA, IHC (p) - ABIN357871 : Aoyama, Okamoto, Kohno, Fukiage, Otsuka, Furu, Ito, Jin, Nagayama, Nakayama, Nakamura, Toguchida: Cell-specific epigenetic regulation of ChM-I gene expression: crosstalk between DNA methylation and histone acetylation. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 3 references for ABIN357871

  2. Chicken Polyclonal LECT1 Primary Antibody for WB - ABIN2781945 : Lafont, Talma, Hopfgarten, Murphy: Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against Leukocyte Cell Derived Chemotaxin 1 Interaction Partners

Human Leukocyte Cell Derived Chemotaxin 1 (LECT1) interaction partners

  1. Data suggest ChM1 as potential tumor suppressor in gastric cancer and useful biomarker for the treatment and prognosis. Its expression was downregulated in cancer tissue, and correlated with advanced stages, lymph node metastasis, and poorer prognosis.

  2. intact 20-25 kDa ChM-I is stored as a component of extracellular matrix in the avascular cartilage zones, but it is inactivated by a single N-terminal proteolytic cleavage in the hypertrophic zone of growth-plate cartilage

  3. the inner meniscus contained larger amounts of ChM-I, and that the inner meniscus-derived ChM-I inhibited endothelial cell proliferation.

  4. Degenerative intervertebral disc cells express ChM-I. Administration of bFGF (show FGF2 Antibodies) down-regulates the expression of ChM-I. Expression is correlated with the degree of degeneration.

  5. Inhibition of YY1 (show YY1 Antibodies) in combination with forced expression of p300 (show EP300 Antibodies) and Sp3 (show SP3 Antibodies) restored the expression of ChM-I in cells with a hypomethylated promoter region, but not in cells with hypermethylation.

  6. Data suggest that chondromodulin-I impairs the VEGF-A (show VEGFA Antibodies)-stimulated motility of endothelial cells by destabilizing lamellipodial extensions.

  7. Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3 (show SP3 Antibodies)

  8. chondromodulin-I has a pivotal role in maintaining valvular normal function by preventing angiogenesis that may lead to valvular heart diseases

  9. Cell-specific epigenetic regulation of ChM-I gene expression

  10. new hypoxia-inducible and SOX9 (show SOX9 Antibodies)-regulated genes, Gdf10 (show GDF10 Antibodies) and Chm-I. In addition, Mig6 (show ERRFI1 Antibodies) and InhbA (show INHBA Antibodies) were induced by hypoxia, predominantly via HIF-2alpha (show EPAS1 Antibodies)

Mouse (Murine) Leukocyte Cell Derived Chemotaxin 1 (LECT1) interaction partners

  1. These findings indicated that Chm-I was an indispensable factor for ectopic cartilage regeneration and the maintenance of cartilage homeostasis.

  2. intact 20-25 kDa ChM-I is stored as a component of extracellular matrix in the avascular cartilage zones, but it is inactivated by a single N-terminal proteolytic cleavage in the hypertrophic zone of growth-plate cartilage

  3. the inhibitory action of ChM-I on trophoblast migration and invasion, implying the potential role of the ChM-I expression in decidual cells for the regulated tissue remodeling and angiogenesis at feto-maternal interface.

  4. chondromodulin 1 stabilizes the chondrocyte phenotype by supporting chondrogenesis but inhibiting chondrocyte hypertrophy and endochondral ossification.

  5. Role of ChM-I in cartilage and eye development

  6. chondromodulin I is a bone remodeling factor

  7. Chondromodulin I suppresses T cell responses and synovial cell proliferation, implying that this cartilage matrix protein (show MATN1 Antibodies) has a therapeutic potential in rheumatoid arthritis.

  8. chondromodulin-I has a pivotal role in maintaining valvular normal function by preventing angiogenesis that may lead to valvular heart diseases

  9. The expression domains of ChM-I and TeM (show TNMD Antibodies) during vertebrate development incorporate the typical avascular regions of the mesenchymal tissues.

  10. results suggest that Chm-I is involved in hypertrophic maturation of periosteal chondrocytes. Although a direct effect of Chm-I on bones is still unclear, bony callus formation was increased while external cartilaginous callus decreased in Chm1(-/-) mice

Leukocyte Cell Derived Chemotaxin 1 (LECT1) Antigen Profile

Protein Summary

This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with LECT1

  • leukocyte cell derived chemotaxin 1 (lect1) antibody
  • leukocyte cell derived chemotaxin 1 (LECT1) antibody
  • leukocyte cell derived chemotaxin 1 (LOC100226280) antibody
  • chondromodulin-I precursor (CHM-I) antibody
  • leukocyte cell derived chemotaxin 1 (Lect1) antibody
  • Bricd3 antibody
  • Chm-1 antibody
  • ChM-I antibody
  • CHM1 antibody
  • chondromodulin-I antibody
  • Lect1 antibody
  • MGC53801 antibody
  • MGC82444 antibody
  • MYETS1 antibody

Protein level used designations for LECT1

leukocyte cell derived chemotaxin 1 , chondromodulin-I , chondromodulin-1-like , chondromodulin-1 , leukocyte cell-derived chemotaxin 1 , BRICHOS domain containing 3 , chondromodulin I , multiple myeloma tumor suppressor 1 , SCGP , small cartilage-derived glycoprotein , Chondromodulin 1 , chM-I

GENE ID SPECIES
379773 Xenopus laevis
446632 Xenopus laevis
694189 Macaca mulatta
735744 Pan troglodytes
100037893 Xenopus (Silurana) tropicalis
100226280 Taeniopygia guttata
100408687 Callithrix jacchus
100455694 Pongo abelii
100008692 Oryctolagus cuniculus
11061 Homo sapiens
395600 Gallus gallus
281683 Bos taurus
16840 Mus musculus
81512 Rattus norvegicus
609613 Canis lupus familiaris
100734572 Cavia porcellus
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