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Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Proteins (LILRA3)

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. Additionally we are shipping Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Antibodies (25) and Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LILRA3 11026 Q8N6C8
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Top Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$806.30
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$618.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$983.48
Details
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days
$160.55
Details

LILRA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , ,

Top referenced Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Proteins

  1. Human LILRA3 Protein expressed in HEK-293 Cells - ABIN2181468 : Arm, Nwankwo, Austen: Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 2 references for ABIN2181468

More Proteins for Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) Interaction Partners

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) interaction partners

  1. Experiments point towards a beneficial role for LILRA3 in virus infections, especially in ssRNA viruses, like HIV, that engage TLR8 (show TLR8 Proteins); however, the potentially beneficial role of LILRA3 is abrogated during a HIV infection.

  2. LILRA3 gene deletion was not associated with Multiple Sclerosis susceptibility and did not affect the age of disease onset, clinical subtype or disease severity.

  3. Evidence showed lack of significant association between LILRA3 deletion and multiple sclerosis pathogenesis. [meta-analysis]

  4. LILRA3 is a new susceptibility factor for systemic lupus erythematosus (SLE) and primary Sjogren's syndrome (pSS (show CDSN Proteins)). It predisposes to certain phenotypes such as leucopenia, thrombocytopenia, autoantibody positivity and increased disease activity.

  5. The current study was conducted to investigate the association of rs103294 of LILRA3 with benign prostatic hyperplasia risk.

  6. ILT6 deletion polymorphism does not appear to be a lupus susceptibility gene in South Indian Tamils, but may behave as a genetic modifier of autoantibody phenotype by influencing the production of anti-Ro60 (show TROVE2 Proteins) and anti-Ro52 (show TRIM21 Proteins) autoantibodies

  7. LILRA3 is an immunostimulatory molecule, whose deficiency is associated with higher frequency of B-non-Hodgkin's lymphoma.

  8. functional LILRA3 is a novel genetic risk factor for rheumatoid arthritis (RA), especially in males. It appears to highly predispose to ACPA (show PRTN3 Proteins)-positive RA and confers an increased risk of disease severity in patients with early RA.

  9. Data did not indicate any association of LILRA3 deletion with multiple sclerosis (MS) susceptibility, however, patients negative for the deletion may begin to suffer from MS significantly earlier than patients who are positive.

  10. LILRA3 binds both classical and non-classical HLA class I (show MICA Proteins) molecules but with reduced affinities compared to LILRB1 (show LILRB1 Proteins)/LILRB2 (show LILRB2 Proteins)

Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) Protein Profile

Protein Summary

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997

Gene names and symbols associated with LILRA3

  • leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 (LILRA3)
  • CD85E protein
  • e3 protein
  • HM31 protein
  • HM43 protein
  • ILT-6 protein
  • ILT6 protein
  • LIR-4 protein
  • LIR4 protein

Protein level used designations for LILRA3

CD85 antigen-like family member E , immunoglobulin-like transcript 6 , leucocyte immunoglobulin-like receptor , leukocyte immunoglobulin-like receptor 4 , leukocyte immunoglobulin-like receptor A3 , leukocyte immunoglobulin-like receptor subfamily A member 3 , monocyte inhibitory receptor HM43/HM31

GENE ID SPECIES
11026 Homo sapiens
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