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LILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Additionally we are shipping LILRB1 Proteins (14) and and many more products for this protein.
Showing 10 out of 85 products:
Human Monoclonal LILRB1 Primary Antibody for FACS, ELISA - ABIN2663612
Kirwan, Burshtyn: Killer cell Ig-like receptor-dependent signaling by Ig-like transcript 2 (ILT2/CD85j/LILRB1/LIR-1). in Journal of immunology (Baltimore, Md. : 1950) 2005
Show all 3 references for ABIN2663612
Human Monoclonal LILRB1 Primary Antibody for FACS - ABIN2659325
Pulford, Micklem, Thomas, Jones, Mason: A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms. in Clinical and experimental immunology 1991
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Human Monoclonal LILRB1 Primary Antibody for FACS - ABIN2660162
McIntire, Morales, Petroff, Colonna, Hunt: Recombinant HLA-G5 and -G6 drive U937 myelomonocytic cell production of TGF-beta1. in Journal of leukocyte biology 2004
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Human Monoclonal LILRB1 Primary Antibody for Func, FACS - ABIN1774726
Banham, Colonna, Cella, Micklem, Pulford, Willis, Mason: Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily. in Journal of leukocyte biology 1999
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Human Monoclonal LILRB1 Primary Antibody for FACS, IHC (fro) - ABIN316937
Colonna, Nakajima, Navarro, López-Botet: A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. in Journal of leukocyte biology 1999
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Human Monoclonal LILRB1 Primary Antibody for FACS - ABIN316939
Borges, Hsu, Fanger, Kubin, Cosman: A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. in Journal of immunology (Baltimore, Md. : 1950) 1998
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Surprisingly, the ability of LIR1(+) natural killer cells to control virus spread differed between human cytomegalovirus strains, and this phenomenon was dependent on amino acid sequences within the viral ligand UL18.
LIR-1 expression on CD8 (show CD8A Antibodies)+ T cells in Rheumatoid Arthritis patients was higher than that in healthy controls.
One SNP in LILRB1 (5724G>A) influenced the risk of NSCLC. 5724G>A was associated with protection from tumor cell infiltration of regional lymph nodes. Expression in tumor tissue correlated with tumor stage.
Our findings offer new insights into the immunopathology of rheumatoid arthritis(RA) patients with long-lasting anti-RA-treatment and highlight the importance to also measure the binding capability of sHLA-G to LILRB1
Data show that the leukocyte antigen (show HLADRB4 Antibodies) G HLA-G (show HLAG Antibodies) alpha1-alpha3 structure, which constitutes the extracellular part of HLA-G2 and HLA-G6, binds the immunologic receptor LILRB2 (show LILRB2 Antibodies) but not LILRB1.
Increased frequency of ILT2-expressing CD56 (show NCAM1 Antibodies)(dim)CD16 (show CD16 Antibodies)(+) NK cells correlates with disease severity of pulmonary tuberculosis.
MiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 (show SETDB1 Antibodies) and reverses the Epithelial-mesenchymal transition of breast cancer stem cells by down regulating the STAT3 (show STAT3 Antibodies) pathway
Patients expressing high levels of CD85j had an impaired ability to lyse triple negative breast cancer cells in the presence of Cetuximab. We also found that CD85j overexpression was associated with HLA-I and soluble HLA-G (show HLAG Antibodies) expression by tumors.
Binding of specific AP-1 (show FOSB Antibodies) factors, we found JunD (show JUND Antibodies) associated with the LILRB1 distal promoter.
These data show that S100A9 (show S100A9 Antibodies) protein, through ligation with CD85j, can stimulate the anti-HIV-1 activity of NK cells.
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
CD85 antigen-like family member J
, Ig-like transcript 2
, leukocyte immunoglobulin-like receptor subfamily B member 1
, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform
, monocyte/macrophage immunoglobulin-like receptor 7