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Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 Proteins (LILRB1)

LILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Additionally we are shipping LILRB1 Antibodies (86) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LILRB1 10859 Q8NHL6
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Top LILRB1 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_HEK-293 Human Fc Tag 50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$269.50
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days
$362.88
Details

LILRB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , , ,

Top referenced LILRB1 Proteins

  1. Human LILRB1 Protein expressed in HEK-293 Cells - ABIN2181470 : Cosman, Fanger, Borges, Kubin, Chin, Peterson, Hsu: A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. in Immunity 1997 (PubMed)
    Show all 4 references for ABIN2181470

More Proteins for Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1) Interaction Partners

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1) interaction partners

  1. Surprisingly, the ability of LIR1(+) natural killer cells to control virus spread differed between human cytomegalovirus strains, and this phenomenon was dependent on amino acid sequences within the viral ligand UL18.

  2. LIR-1 expression on CD8 (show CD8A Proteins)+ T cells in Rheumatoid Arthritis patients was higher than that in healthy controls.

  3. One SNP in LILRB1 (5724G>A) influenced the risk of NSCLC. 5724G>A was associated with protection from tumor cell infiltration of regional lymph nodes. Expression in tumor tissue correlated with tumor stage.

  4. Our findings offer new insights into the immunopathology of rheumatoid arthritis(RA) patients with long-lasting anti-RA-treatment and highlight the importance to also measure the binding capability of sHLA-G to LILRB1

  5. Data show that the leukocyte antigen (show HLADRB4 Proteins) G HLA-G (show HLAG Proteins) alpha1-alpha3 structure, which constitutes the extracellular part of HLA-G2 and HLA-G6, binds the immunologic receptor LILRB2 (show LILRB2 Proteins) but not LILRB1.

  6. Increased frequency of ILT2-expressing CD56 (show NCAM1 Proteins)(dim)CD16 (show CD16 Proteins)(+) NK cells correlates with disease severity of pulmonary tuberculosis.

  7. MiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 (show SETDB1 Proteins) and reverses the Epithelial-mesenchymal transition of breast cancer stem cells by down regulating the STAT3 (show STAT3 Proteins) pathway

  8. Patients expressing high levels of CD85j had an impaired ability to lyse triple negative breast cancer cells in the presence of Cetuximab. We also found that CD85j overexpression was associated with HLA-I and soluble HLA-G (show HLAG Proteins) expression by tumors.

  9. Binding of specific AP-1 (show FOSB Proteins) factors, we found JunD (show JUND Proteins) associated with the LILRB1 distal promoter.

  10. These data show that S100A9 (show S100A9 Proteins) protein, through ligation with CD85j, can stimulate the anti-HIV-1 activity of NK cells.

LILRB1 Protein Profile

Protein Summary

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LILRB1

  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1)
  • CD85J protein
  • ILT-2 protein
  • ILT2 protein
  • LIR-1 protein
  • LIR1 protein
  • MIR-7 protein
  • MIR7 protein

Protein level used designations for LILRB1

CD85 antigen-like family member J , Ig-like transcript 2 , leukocyte immunoglobulin-like receptor subfamily B member 1 , leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform , monocyte/macrophage immunoglobulin-like receptor 7

GENE ID SPECIES
10859 Homo sapiens
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