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Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 (LILRB3) ELISA Kits

LILRB3 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Additionally we are shipping Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 Antibodies (35) and Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat LILRB3 LILRB3 65146  
Anti-Human LILRB3 LILRB3 11025 O75022
Anti-Mouse LILRB3 LILRB3 18733 P97484
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More ELISA Kits for Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 Interaction Partners

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 (LILRB3) interaction partners

  1. RPS9 (show RPS9 ELISA Kits)/LILRB3 (rs11666543) was associated with Takayasu arteritis.

  2. Blockade of LILRB1 and LILRB3 receptors by monoclonal antibodies or short interfering RNA (siRNA) abrogated the specific antigen-presenting properties of dendritic cells, implying an important regulatory role of these molecules.

  3. Coligation of LIR3 to LIR7 or to FcepsilonRI (show FCER1G ELISA Kits) by means of a second monoclonal antibody significantly inhibited net histamine release, cysLT production, and IL-4 (show IL4 ELISA Kits) generation. LIR3 is counter-regulatory for both adaptive and innate receptors suggests.

  4. Progenitor mast cells expressed cell surface inhibitory LILRB3. Mature cord-blood-derived mast cells had detectable mRNA encoding multiple LILRs, none were expressed on the cell surface.

  5. LILRB3 is expressed on cultured osteoclast precursor cells derived from peripheral blood monocytes and plays a regulatory role in the development of osteoclasts.

Mouse (Murine) Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 (LILRB3) interaction partners

  1. neural plasticity in adult visual cortex is actively repressed and can be enhanced by blocking PirB function.

  2. The Nogo-B (show RTN4 ELISA Kits)-PirB axis controls macrophage-mediated vascular remodeling.

  3. PIRB and LILRB2 (show LILRB2 ELISA Kits) were expressed in mouse and human platelets, respectively.

  4. NogoA (show RTN4 ELISA Kits) receptors, NogoR1 and PirB, are expressed in the ventricular zone where neural stem cells reside.

  5. PirB expression is up-regulated after transient focal cerebral ischaemia. It may play pathologic roles in the inhibition of axonal regeneration after stroke.

  6. PirB normally regulates spine and excitatory synapse density and consequently the threshold for new learning throughout life.

  7. Data indicate a critical role for PIR-B and PIR-A in eosinophil development.

  8. In mice, the deleterious effect of Abeta (show APP ELISA Kits) oligomers on hippocampal long-term potentiation required PirB, and in a transgenic model of Alzheimer's disease, PirB not only contributed to memory deficits present in adult mice, but also mediated loss of synaptic plasticity in juvenile visual cortex.

  9. a key role for PIR-B in IPF, likely via the regulation of macrophage activation

  10. findings, coupled with previous studies, may imply that PirB is probably a critical molecule in inhibition of axonal regeneration by myelin inhibitors after ON injury

Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 (LILRB3) Antigen Profile

Antigen Summary

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LILRB3

  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (Lilrb3) antibody
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like (Lilrb3l) antibody
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 (LILRB5) antibody
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3) antibody
  • paired Ig-like receptor B (Pirb) antibody
  • CD85A antibody
  • Gp91 antibody
  • HL9 antibody
  • ILT-5 antibody
  • ILT5 antibody
  • LILRA6 antibody
  • LILRB3 antibody
  • LIR-3 antibody
  • LIR3 antibody
  • NILR-1 antibody
  • Pir-A1 antibody
  • Pir-A2 antibody
  • PIR-B antibody
  • PIRB antibody

Protein level used designations for LILRB3

paired-Ig-like receptor B , type 1 one-pass transmembrane Ig-like receptor , Ig-superfamily activating receptor , leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 , paired Ig-like receptor-A1 , paired Ig-like receptor-A2 , paired Ig-like receptor-B , six Ig-like domains/type I transmembrane , CD85 antigen-like family member A , immunoglobulin-like transcript 5 , leukocyte immunoglobulin-like receptor 3 , leukocyte immunoglobulin-like receptor subfamily B member 3 , leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 , monocyte inhibitory receptor HL9 , cell-surface glycoprotein p91 , paired immunoglobulin-like receptor B

GENE ID SPECIES
65146 Rattus norvegicus
361493 Rattus norvegicus
484306 Canis lupus familiaris
790139 Bos taurus
11025 Homo sapiens
18733 Mus musculus
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