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LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Additionally we are shipping LILRB4 Antibodies (61) and and many more products for this protein.
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Identification of ILT4 (show LILRB2 ELISA Kits) as a cellular receptor for CSP (show DNAJC5 ELISA Kits) C4d
involvement of ILT3 and ILT4 (show LILRB2 ELISA Kits) in the modulation of immune responsiveness in multiple sclerosis by both interferon (show IFNA ELISA Kits) and vitamin D
Cyclosporine up-regulated the expression of ILT3 and ILT4 (show LILRB2 ELISA Kits) on natural killer cells, which influenced their cytotoxicity against tumor cells.
Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance.
Data show that LILRB4 is a potent inhibitor of monocyte activation via FcgammaRI (show FCGR1A ELISA Kits).
report that ILT2 receptor, ILT3 receptor, ILT4 (show LILRB2 ELISA Kits) receptor, and KIR2DL4 (show KIR2DL4 ELISA Kits) receptor expression is up-regulated by HLA-G (show HLAG ELISA Kits) histocompatibility antigen in antigen-presenting cells, natural killer cells, and T cells
ILT3 precursor RNA is expressed and retained in nuclei of resting endothelial cells.
Our findings indicate that expression of ILT3 and ILT4 (show LILRB2 ELISA Kits) on CLL B cells represents a phenotypic abnormality that may play a role in tolerization of tumor-specific T cells.
The inhibitory effect of serum and membrane ILT3 in a humanized SCID (show PRKDC ELISA Kits) mouse model describes an immune-escape mechanism that could contribute to impaired T cell responses in patients with cancer.
Both membrane and soluble ILT3 are proteins with potent immunosuppressive activity which are of importance for treatment of rejection, autoimmunity and cancer.
Results suggest that plasma cell development from memory and marginal zone B cells, as well as subsequent antibody production, are suppressed via glycoprotein 49B (gp49B).
LILRB4 can downregulate the development of pathologic allergic inflammation.
receptor attenuates the number of these mature DCs and attendant IL-4 (show IL4 ELISA Kits)-producing lymphocytes in the lymph nodes, and accordingly, the ability of DCs to elicit pathologic Th2 pulmonary inflammation
Gp49B1 is a unique inhibitory receptor that is induced in multiple lineages of innate and adaptive immune cells during an infection and controls their IFN-gamma (show IFNG ELISA Kits), but not cytotoxic responses.
Expression of gp49B was detected on peripheral eosinophils of control mice and on eosinophils from lungs of mice treated with RW, suggesting a role for gp49B on eosinophils in dampening allergic inflammatory responses.
study reports that gp49B, is expressed on dendritic cells and downregulates cellular activity to prevent the excessive activation of T cells in vitro and in vivo
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
, CD85 antigen-like family member K
, immunoglobulin-like transcript 3
, leukocyte immunoglobulin-like receptor 5
, leukocyte immunoglobulin-like receptor subfamily B member 4
, monocyte inhibitory receptor HM18
, glycoprotein 49 B
, mast cell surface glycoprotein Gp49B