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LILRB3 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Additionally we are shipping Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 3 Proteins (19) and many more products for this protein.
Showing 10 out of 71 products:
Human Monoclonal LILRB3 Primary Antibody for CyTOF, FACS - ABIN4899821
Pfistershammer, Lawitschka, Klauser, Leitner, Weigl, Heemskerk, Pickl, Majdic, Böhmig, Fischer, Greinix, Steinberger: Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients. in Blood 2009
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Human Monoclonal LILRB3 Primary Antibody for CyTOF, FACS - ABIN4899820
Masuda, Nakamura, Maeda, Sakamoto, Takai: Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation. in The Journal of experimental medicine 2007
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Mouse (Murine) Monoclonal LILRB3 Primary Antibody for CyTOF, FACS - ABIN4899844
Thams, Brodin, Plantman, Saxelin, Kärre, Cullheim: Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
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Mouse (Murine) Monoclonal LILRB3 Primary Antibody for FACS - ABIN4896799
Zheng, Umikawa, Cui, Li, Chen, Zhang, Huynh, Hyunh, Kang, Silvany, Wan, Ye, Cantó, Chen, Wang, Ward, Zhang: Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development. in Nature 2012
RPS9 (show RPS9 Antibodies)/LILRB3 (rs11666543) was associated with Takayasu arteritis.
Blockade of LILRB1 (show LILRB1 Antibodies) and LILRB3 receptors by monoclonal antibodies or short interfering RNA (siRNA) abrogated the specific antigen-presenting properties of dendritic cells, implying an important regulatory role of these molecules.
Coligation of LIR3 to LIR7 (show LILRA2 Antibodies) or to FcepsilonRI (show FCER1G Antibodies) by means of a second monoclonal antibody significantly inhibited net histamine release, cysLT production, and IL-4 (show IL4 Antibodies) generation. LIR3 is counter-regulatory for both adaptive and innate receptors suggests.
Progenitor mast cells expressed cell surface inhibitory LILRB3. Mature cord-blood-derived mast cells had detectable mRNA encoding multiple LILRs, none were expressed on the cell surface.
LILRB3 is expressed on cultured osteoclast precursor cells derived from peripheral blood monocytes and plays a regulatory role in the development of osteoclasts.
peripheral CD4 (show CD4 Antibodies)+ T cells from spontaneous murine arthritis model frequently express PIR-B
These results provide evidence for a critical role of the major histocompatibility complex class I/PirB signaling system in the generation of asymmetries in hippocampal circuitry.
These data identify paired Ig-like receptor B as a molecular checkpoint in IL-13 (show IL13 Antibodies)-induced eosinophil accumulation and activation
the overexpression of PirB inhibits the neuronal survival through increased neuron apoptosis
neural plasticity in adult visual cortex is actively repressed and can be enhanced by blocking PirB function.
The Nogo-B (show RTN4 Antibodies)-PirB axis controls macrophage-mediated vascular remodeling.
PIRB and LILRB2 (show LILRB2 Antibodies) were expressed in mouse and human platelets, respectively.
NogoA (show RTN4 Antibodies) receptors, NogoR1 and PirB, are expressed in the ventricular zone where neural stem cells reside.
PirB expression is up-regulated after transient focal cerebral ischaemia. It may play pathologic roles in the inhibition of axonal regeneration after stroke.
PirB normally regulates spine and excitatory synapse density and consequently the threshold for new learning throughout life.
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
paired-Ig-like receptor B
, type 1 one-pass transmembrane Ig-like receptor
, Ig-superfamily activating receptor
, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
, paired Ig-like receptor-A1
, paired Ig-like receptor-A2
, paired Ig-like receptor-B
, six Ig-like domains/type I transmembrane
, CD85 antigen-like family member A
, immunoglobulin-like transcript 5
, leukocyte immunoglobulin-like receptor 3
, leukocyte immunoglobulin-like receptor subfamily B member 3
, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
, monocyte inhibitory receptor HL9
, cell-surface glycoprotein p91
, paired immunoglobulin-like receptor B