anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) Antibodies

The protein encoded by LAIR1 is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Additionally we are shipping LAIR1 Proteins (22) and LAIR1 Kits (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAIR1 52855 Q8BG84
LAIR1 3903 Q6GTX8
LAIR1 574531 P0C1X9
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Top anti-LAIR1 Antibodies at antibodies-online.com

Showing 10 out of 229 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, FACS, IHC (p), WB Profile of LAIR-1 positive PBMC (cells analyzed by flow cytometry using ABIN121146). 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB LAIR1 Antibody (Center) (ABIN657706) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the LAIR1 antibody detected the LAIR1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse PE FACS Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN LAIR-1:RPE (ABIN119873). 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Mouse FITC FACS Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN LAIR-1:FITC (ABIN119869). 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated FACS, IP, WB Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD305 (ABIN119872). 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Mouse PE FACS Detection of LAIR1 in Human Lymphocytes by Flow Cytometry. Human lymphocytes were stained with Mouse Anti-Human LAIR1 PE-conjugated Monoclonal Antibody. Detection of LAIR1 in Human Lymphocytes by Flow Cytometry. Human lymphocytes were stained with Mouse Anti-Human LAIR1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$325.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of LAIR-1 on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human LAIR-1 antibody. 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LAIR1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western blot analysis LAIR-1 on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). Lane 1: 250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human LAIR-1 antibody. 150 μg Log in to see 6 to 8 Days
$398.54
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LAIR1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details

LAIR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LAIR1 Antibodies

  1. Human Monoclonal LAIR1 Primary Antibody for FACS, IP - ABIN1690731 : Poggi, Tomasello, Ferrero, Zocchi, Moretta: p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor. in European journal of immunology 1998 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal LAIR1 Primary Antibody for FACS, IP - ABIN1690739 : Poggi, Tomasello, Revello, Nanni, Costa, Moretta: p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes. in International immunology 1997 (PubMed)
    Show all 7 Pubmed References

  3. Human Monoclonal LAIR1 Primary Antibody for FACS - ABIN4896415 : Rodríguez-Bayona, Ramos-Amaya, Brieva: Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation. in Immunology letters 2010 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal LAIR1 Primary Antibody for FACS - ABIN2689802 : Xu, Zhao, Zhao: Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal LAIR1 Primary Antibody for FACS, IP - ABIN2479896 : Leopold, Charleux: [Continuous corneal suture]. in Bulletin des sociétés d'ophtalmologie de France 1976 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal LAIR1 Primary Antibody for FACS - ABIN2479899 : Poggi, Pella, Morelli, Spada, Revello, Sivori, Augugliaro, Moretta, Moretta: p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans. in European journal of immunology 1995 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal LAIR1 Primary Antibody for ELISA, WB - ABIN4229006 : Tang, Narayanan, Peruzzi, Apara, Natarajan, Margulies, Coligan, Borrego: A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

  8. Human Monoclonal LAIR1 Primary Antibody for CyTOF, FACS - ABIN4899640 : Cabezón, Sintes, Llinàs, Benitez-Ribas: Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. in Immunology letters 2010 (PubMed)

More Antibodies against LAIR1 Interaction Partners

Mouse (Murine) Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) interaction partners

  1. LAIR-1 in megakaryocytes leads to increased Src (show SRC Antibodies) family kinase activity and downstream signaling in response to collagen that is transmitted to platelets, rendering them hyper-reactive specifically to agonists that signal through Syk (show SYK Antibodies) tyrosine kinases.

  2. The LAIR1-SHP-1 (show PTPN6 Antibodies)-CAMK1 (show CAMK1 Antibodies)-CREB (show CREB1 Antibodies) pathway sustains the survival and self-renewal of AML (show RUNX1 Antibodies) stem cells.

  3. LAIR-1-deficient mice are healthy and fertile with normal longevity, showing increased numbers of splenic B, regulatory T, and dendritic cells.

  4. tumor-expressed collagens can bind and trigger immune inhibitory signaling via LAIR-1, suggesting that collagens indeed may affect tumor immune evasion.

  5. Mouse Lair-1 cytoplasmic tail can become phosphorylated, thereby recruiting SH2 (show MYO15 Antibodies)-containing tyrosine phosphatase-2 (SHP-2 (show PTPN11 Antibodies)). Unlike human LAIR-1, SHP-1 (show PTPN6 Antibodies) is not recruited to the mouse Lair-1 cytoplasmic tail.

  6. analysis of leukocyte Ig-like receptor (show LILRA6 Antibodies) signaling and crystal structure of disulfide-linked HLA-G (show HLAG Antibodies) dimer

  7. findings show that mLAIR-1 interacted with high affinity with a wide range of collagen molecules; mLAIR-1 cross-linking with its ligands inhibits CD3 (show CD3E Antibodies)-induced T cell stimulation in vitro

Human Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) interaction partners

  1. We suggest that LAIR1 and LAIR2 (show LAIR2 Antibodies) genetic variants are associated with regulation of gene expression and variable pemphigus foliaceus (show DSG1 Antibodies) susceptibility, and show indirect association of LAIR2 (show LAIR2 Antibodies) differential mRNA expression with pemphigus foliaceus (show DSG1 Antibodies) pathogenesis.

  2. A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens;findings illustrate, with a biologically relevant example, a novel mechanism of antibody diversification by interchromosomal DNA transposition

  3. C1q-mediated repression of human monocytes is regulated by LAIR-1

  4. The LAIR1-SHP-1 (show PTPN6 Antibodies)-CAMK1 (show CAMK1 Antibodies)-CREB (show CREB1 Antibodies) pathway sustains the survival and self-renewal of AML (show RUNX1 Antibodies) stem cells.

  5. These data suggest that LAIR-1 has a relevant impact on EOC progression and may be helpful for a better understanding of molecular pathogenesis of cancer.

  6. LAIR1 expression is a reliable and inexpensive marker capable of independently predicting time to first treatment in newly diagnosed unselected patients with chronic lymphocytic leukemia.

  7. The expression of LAIR -1 on pDCs of juvenile systemic lupus erythematosus patients was significantly lower than that of control patients.

  8. a novel pathway for the immunomodulatory functions of SP-D (show SFTPD Antibodies) mediated via binding of its collagenous domains to LAIR-1.

  9. LAIR-1 may play an important role in immune imbalance in children with immune thrombocytopenia.

  10. Studies indicate that Megakaryocyte maturation is accompanied by up-regulation of glycoprotein VI and down-regulation of leukocyte-associated immunoglobulin-like receptor-1.

LAIR1 Antigen Profile

Protein Summary

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.

Gene names and symbols associated with LAIR1

  • leukocyte-associated Ig-like receptor 1 (Lair1) antibody
  • leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) antibody
  • leukocyte-associated immunoglobulin-like receptor 1 (Lair1) antibody
  • 5133400O11Rik antibody
  • BB115266 antibody
  • CD305 antibody
  • D7Bwg0421e antibody
  • LAIR-1 antibody
  • mLair-1 antibody

Protein level used designations for LAIR1

leukocyte-associated immunoglobulin-like receptor 1 , mLAIR1 , hLAIR1 , leukocyte-associated Ig-like receptor 1 , LAIR-1 , leukocyte-associated Ig-like receptor-1 , rLAIR1

GENE ID SPECIES
52855 Mus musculus
3903 Homo sapiens
574531 Rattus norvegicus
Selected quality suppliers for anti-LAIR1 (LAIR1) Antibodies
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