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Leukotriene C4 Synthase Proteins (LTC4S)

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. Additionally we are shipping Leukotriene C4 Synthase Antibodies (27) and Leukotriene C4 Synthase Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LTC4S 4056 Q16873
LTC4S 17001 Q60860
Rat LTC4S LTC4S 114097 Q925U2
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Top Leukotriene C4 Synthase Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

LTC4S Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Leukotriene C4 Synthase (LTC4S) Interaction Partners

Human Leukotriene C4 Synthase (LTC4S) interaction partners

  1. Biochemical and structural characterization of LTC4S mutants along with crystal structures of the wild type and mutated enzymes in complex with three product analogs, provide new insights to binding of substrates and product.

  2. The results of our study failed to confirm whether the selected variants in LTC4S gene within the LT metabolism pathway contribute to platelet reactivity in a diabetic population treated with ASA (show ARSA Proteins).

  3. Elevated levels of leukotriene C4 synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients.

  4. genetic association studies in population of Han Chinese in Eastern China: Data suggest that an SNP in LTC4S (rs730012) is associated with risk of ischemic stroke; carriers of C allele of rs730012 in LTC4S are most susceptible to ischemic stroke.

  5. meta-analysis suggested that the -444A/C polymorphism in the LTC4S gene would be a risk factor for asthma in Caucasians and aspirin-tolerant populations

  6. A significant association has been found between the -1072G/A (rs3776944) SNP in the LTC4S gene and atopic asthma in the family-based analysis.

  7. The SNPs of ALOX(5 (show ALOX5 Proteins))AP and LTC(4)S are associated with asthma.

  8. investigation of catalytic mechanism of LTC4S: Data suggest that glutathione thiolate anion formation in LTC4S is not rate-limiting for overall reaction of leukotriene C4 production. Thiolate anion is stabilized by Arg104 at all three active sites.

  9. Polymorphisms of the PTGDR (show PTGDR Proteins) and LTC4S influence responsiveness to leukotriene receptor antagonists in Korean children with asthma.

  10. The catalytic architecture of leukotriene C4 synthase with two arginine residues.

Mouse (Murine) Leukotriene C4 Synthase (LTC4S) interaction partners

  1. These results suggest that LTC(4) synthase, thought to be specific for the conjugation of GSH to LTA(4), can also recognize 5-oxoETE as an electrophilic substrate.

  2. Expression of leukotriene C4 synthase mRNA in the choroid plexus.

  3. LTC4 synthase was selectively localized in the vasopressinergic magnocellular neurons of the hypothalamic paraventricular, supraoptic and suprachiasmatic nuclei and in the retrochiasmatic area.

Leukotriene C4 Synthase (LTC4S) Protein Profile

Protein Summary

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum.

Gene names and symbols associated with LTC4S

  • leukotriene C4 synthase (LTC4S)
  • leukotriene C4 synthase, gene 1 (ltc4s.1)
  • leukotriene C4 synthase (Ltc4s)
  • ltc4s protein

Protein level used designations for LTC4S

leukotriene C4 synthase , LTC4 synthase , leukotriene-C(4) synthase

GENE ID SPECIES
416289 Gallus gallus
705233 Macaca mulatta
739986 Pan troglodytes
770665 Gallus gallus
100379825 Xenopus (Silurana) tropicalis
4056 Homo sapiens
17001 Mus musculus
114097 Rattus norvegicus
511749 Bos taurus
100725689 Cavia porcellus
607316 Canis lupus familiaris
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