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Leupaxin (LPXN) ELISA Kits

The product encoded by LPXN is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Additionally we are shipping Leupaxin Antibodies (46) and Leupaxin Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LPXN 9404 O60711
LPXN 107321 Q99N69
Anti-Rat LPXN LPXN 293783  
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Top Leupaxin ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for Leupaxin Interaction Partners

Human Leupaxin (LPXN) interaction partners

  1. The full-length leupaxin binds to the Pyk2 (show PTK2B ELISA Kits)-focal adhesion targeting domain.

  2. Authors demonstrate that LPXN directly influences cytoskeletal dynamics via interaction with the actin-binding protein CaD (show CAD ELISA Kits) and regulates CaD (show CAD ELISA Kits) phosphorylation by recruiting ERK (show EPHB2 ELISA Kits) to highly dynamic structures within PCa (show FLVCR1 ELISA Kits) cells.

  3. Results show that leupaxin has particular influence on the progression and invasion of breast cancer cells and may therefore represent an interesting candidate protein for diagnosis and therapeutic interventions.

  4. first evidence of dynamic regulation of leupaxin localization and tyrosine phosphorylation by G-Protein Coupled Receptors

  5. leupaxin functions as a paxillin (show PXN ELISA Kits) counterpart that potently suppresses the tyrosine phosphorylation of paxillin (show PXN ELISA Kits) during integrin signaling.

  6. leupaxin may be a critical nucleating component of the osteoclast podosomal signaling complex

  7. Leupaxin binding to tyrosine phosphatase PEP suggests that leupaxin may function as a signal-transducing complex with PEP.

  8. These data demonstrate that LPXN forms a signaling complex with Pyk2 (show PTK2B ELISA Kits), c-Src (show SRC ELISA Kits), and PTP-PEST (show PTPN12 ELISA Kits) to regulate migration of prostate cancer cells.

  9. Leupaxin plays an inhibitory role in BCR (show BCR ELISA Kits) signaling and B cell function.

  10. leupaxin could serve as a potential progression marker for a subset of PCa (show FLVCR1 ELISA Kits) and may represent a novel coactivator of the androgen receptor (show AR ELISA Kits)

Mouse (Murine) Leupaxin (LPXN) interaction partners

  1. leupaxin functions as a paxillin (show PXN ELISA Kits) counterpart that potently suppresses the tyrosine phosphorylation of paxillin (show PXN ELISA Kits) during integrin signaling.

  2. leupaxin may be a critical nucleating component of the osteoclast podosomal signaling complex

  3. Association of the scaffold protein (show HOMER1 ELISA Kits) LPXN with Src (show SRC ELISA Kits) adds further complexity to the organization of the podosomal signaling complex in osteoclasts.

  4. Leupaxin plays an inhibitory role in BCR (show BCR ELISA Kits) signaling and B cell function.

  5. Leupaxin is enriched in mouse vascular smooth muscle and its expression is dynamically regulated during development.

Leupaxin (LPXN) Antigen Profile

Antigen Summary

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with Leupaxin (LPXN) ELISA Kits

  • leupaxin (LPXN) antibody
  • si:rp71-15d4.1 (si:rp71-15d4.1) antibody
  • leupaxin (PAAG_03110) antibody
  • leupaxin (PGTG_11441) antibody
  • Leupaxin (lpxn) antibody
  • leupaxin (Lpxn) antibody
  • 4933402K05Rik antibody
  • A530083L21Rik antibody
  • AV278559 antibody
  • LDPL antibody
  • MGC140379 antibody

Protein level used designations for Leupaxin (LPXN) ELISA Kits

leupaxin , Leupaxin

GENE ID SPECIES
281277 Bos taurus
423129 Gallus gallus
451205 Pan troglodytes
483465 Canis lupus familiaris
513264 Bos taurus
560743 Danio rerio
702033 Macaca mulatta
9097993 Paracoccidioides sp. 'lutzii' Pb01
10527262 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100066577 Equus caballus
100196515 Salmo salar
100394284 Callithrix jacchus
100445873 Pongo abelii
100592030 Nomascus leucogenys
9404 Homo sapiens
107321 Mus musculus
293783 Rattus norvegicus
100008712 Oryctolagus cuniculus
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